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Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
March 16, 2006
Volume 16, No. 11

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Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in a cohort of 1,000 neonates in Madrid (Spain)
Ropero P, et al.
Ann Hematol 2006 Mar

 

Infectious and Parasitic Diseases

Variant IRAK-1 Haplotype is Associated with Increased NF-{kappa}B Activation and Worse Outcomes in Sepsis
Arcaroli J, et al.
Am J Respir Crit Care Med 2006 Mar

 

Neoplasms

TGF-beta1 gene polymorphisms influence the course of the disease in non-Hodgkin's lymphoma patients
Mazur G, et al.
Cytokine 2006 Mar

Association of polymorphic variants in endothelin-1 (EDN1) genes with the therapy of patients with cutaneous T-cell lymphomas
Vasku V, et al.
Cas Lek Cesk 2006;145(2):144-7

Interleukin-1beta gene polymorphism associated with hepatocellular carcinoma in hepatitis B virus infection
Hirankarn N, et al.
World J Gastroenterol 2006 Feb;12(5):776-9

Polymorphisms in DNA damage binding protein 2 (DDB2) and susceptibility of primary lung cancer in Chinese: a case-control study
Hu Z, et al.
Carcinogenesis 2006 Mar

Cytotoxic T lymphocyte antigen-4 promoter variants in breast cancer
Erfani N, et al.
Cancer Genet Cytogenet 2006 Mar;165(2):114-20

TP53 codon 72 polymorphism in radiation-associated human papillary thyroid cancer
Rogounovitch TI, et al.
Oncol Rep 2006 Apr;15(4):949-56

Glutathione S-transferase polymorphisms and ovarian cancer treatment and survival
Beeghly A, et al.
Gynecol Oncol 2006 Feb;100(2):330-7

Association between the polymorphism of CYP17 gene and risk of prostate cancer in chinese vigurs men
Guli MR, et al.
Zhonghua Nan Ke Xue 2006 Feb;12(2):120-2

Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study
Iacopetta B, et al.
Ann Oncol 2006 Mar

Single Nucleotide Polymorphisms of RecQ1, RAD54L and ATM Genes Are Associated With Reduced Survival of Pancreatic Cancer
Li D, et al.
J Clin Oncol 2006 Mar

 

Endocrine, Nutritional and Metabolic Diseases

Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases
Smyth DJ, et al.
BMC Med Genet 2006 Mar;7(1):20

Smoking and obesity make a bad problem worse: genetics and lifestyle affect high density lipoprotein levels in Turks
Hodoglugil U & Mahley RW
Anadolu Kardiyol Derg 2006 Mar;6(1):60-7

ENPP1, the first example of common genetic link between childhood and adult obesity and type 2 diabetes
Meyre D & Froguel P
Med Sci (Paris) 2006 Mar;22(3):308-12

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population
Lindner I, et al.
Mol Nutr Food Res 2006 Mar;50(3):270-4

Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population
Devlin AM, et al.
Am J Clin Nutr 2006 Mar;83(3):708-13

Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations
Gueant-Rodriguez RM, et al.
Am J Clin Nutr 2006 Mar;83(3):701-7

Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production
Hall WL, et al.
Am J Clin Nutr 2006 Mar;83(3):592-600

 

Mental Disorders

Evaluation of RGS4 as a candidate gene for schizophrenia
Liu YL, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

The effect of dopamine D2, D5 receptor and transporter (SLC6A3) polymorphisms on the cue-elicited heroin craving in Chinese
Li Y, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skills
Yirmiya N, et al.
Mol Psychiatry 2006 Mar

Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder
Nievergelt CM, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

Smoking cessation, weight gain, and DRD4 -521 genotype
Munafo MR, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

Linkage and association of schizophrenia with genetic variations in the locus of neuregulin 1 in Korean population
Kim JW, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

Association of the NRG1 gene and schizophrenia: a meta-analysis
Munafo MR, et al.
Mol Psychiatry 2006 Mar

Serotonin transporter gene promoter region polymorphism associated with poststroke major depression
Ramasubbu R, et al.
J Neuropsychiatry Clin Neurosci 2006 Winter;18(1):96-9

MAOA-uVNTR polymorphism in a Brazilian sample: Further support for the association with impulsive behaviors and alcohol dependence
Contini V, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

Glutamate AMPA receptor subunit 1 gene (GRIA1) and DSM-IV-TR schizophrenia: A pilot case-control association study in an Italian sample
Magri C, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

Serotonin transporter gene promoter polymorphism predicts SSRI response in generalized social anxiety disorder
Stein MB, et al.
Psychopharmacology (Berl) 2006 Mar

Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population
Chen QY, et al.
J Psychiatr Res 2006 Mar

Association of the Val158Met Catechol O-Methyltransferase Genetic Polymorphism with Panic Disorder
Rothe C, et al.
Neuropsychopharmacology 2006 Mar

Association of the DAT1 polymorphism with attention deficit hyperactivity disorder (ADHD): A family-based approach
Lim MH, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

 

Diseases of the Nervous System and Sense Organs

Influence of Angiotensin-converting enzyme polymorphism on neuropsychological subacute performance in moderate and severe traumatic brain injury
Ariza M, et al.
J Neuropsychiatry Clin Neurosci 2006 Winter;18(1):39-44

Lack of association between UBQLN1 and Alzheimer disease
Slifer MA, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

 

Diseases of the Circulatory System

Pharmacogenetics of chronic heart failure--beta blockers
Vasku A, et al.
Cas Lek Cesk 2006;145(2):148-52; discussion
152-3

IL-10 genotype predicts serum levels of adhesion molecules, inflammation and atherosclerosis in hemodialysis patients
Kahraman S, et al.
J Nephrol 2006 Jan-2006 Feb;19(1):50-6

Association study between fibronectin and coronary heart disease
Zhang Y, et al.
Clin Chem Lab Med 2006;44(1):37-42

Association of angiotensin II type 1 receptor gene polymorphism with carotid atherosclerosis
Zhu S & Meng QH
Clin Chem Lab Med 2006;44(3):282-4

Associations of apolipoprotein E exon 4 and lipoprotein lipase S447X polymorphisms with acute ischemic stroke and myocardial infarction
Baum L, et al.
Clin Chem Lab Med 2006;44(3):274-81

Relations of apolipoprotein E promoter polymorphisms and haplotypes to plasma low-density and total cholesterol levels and markers of subclinical atherosclerosis in the 21-year follow-up of the the cardiovascular risk in Young Finns study
Viiri LE, et al.
J Lipid Res 2006 Mar

A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis
Corral J, et al.
Blood 2006 Mar

A single nucleotide polymorphism of macrophage migration inhibitory factor is related to inflammatory response in coronary bypass surgery using cardiopulmonary bypass
Lehmann LE, et al.
Eur J Cardiothorac Surg 2006 Mar

Does G8002A polymorphism in endothelin gene have a meaning for other risks at the patients with heart failure?
Spinarova L, et al.
Vnitr Lek 2006 Jan;52(1):34-9

 

Diseases of the Respiratory System

Polymorphisms in chemokine and chemokine receptor genes and the development of coal workers' pneumoconiosis
Nadif R, et al.
Cytokine 2006 Mar

Estrogen receptor 1 polymorphisms are associated with airway hyperresponsiveness and lung function decline, particularly in female subjects with asthma
Dijkstra A, et al.
J Allergy Clin Immunol 2006 Mar;117(3):604-11

MMP14 gene polymorphisms in chronic obstructive pulmonary disease
Saitoh W, et al.
Int J Mol Med 2006 Apr;17(4):621-6

G protein-coupled receptor 154 gene polymorphism is associated with airway hyperresponsiveness to methacholine in a Chinese population
Feng Y, et al.
J Allergy Clin Immunol 2006 Mar;117(3):612-7

 

Diseases of the Digestive System

Polymorphisms in the organic cation transporter genes SLC22A4 and SLC22A5 and Crohn's disease in a New Zealand Caucasian cohort
Leung E, et al.
Immunol Cell Biol 2006 Apr;84(2):233-6

GSTM1 polymorphism and oral leukoplakia
Duarte EC, et al.
J Oral Pathol Med 2006 Apr;35(4):202-5

 

Diseases of the Genitourinary System

The influence of the endothelin-converting enzyme-1 gene polymorphism on the progression of autosomal dominant polycystic kidney disease
Reiterova J, et al.
Ren Fail 2006;28(1):21-4

CYP17, CYP1A1 and COMT polymorphisms and the risk of adenomyosis and endometriosis in Taiwanese women
Juo SH, et al.
Hum Reprod 2006 Mar

Genetic polymorphism of vascular endothelial growth factor: impact on progression of IgA nephropathy
Chow KM, et al.
Ren Fail 2006;28(1):15-20

 

Complications of Pregnancy, Childbirth, and the Puerperium

Association of insulin receptor substrate-1 G972R variant with baseline characteristics of the patients with gestational diabetes mellitus
Tok EC, et al.
Am J Obstet Gynecol 2006 Mar;194(3):868-72

 

Diseases of the Musculoskeletal System and Connective Tissue

ALDH2 polymorphisms and bone mineral density in an elderly Japanese population
Yamaguchi J, et al.
Osteoporos Int 2006 Mar

Renin-angiotensin system gene polymorphisms: association with susceptibility to Henoch-Schonlein purpura and renal involvement
Ozkaya O, et al.
Clin Rheumatol 2006 Mar

 

Congenital Anomalies

Maternal MTHFR 677C>T is a risk factor for congenital heart defects: effect modification by periconceptional folate supplementation
van Beynum IM, et al.
Eur Heart J 2006 Mar

 

Certain Conditions Originating in the Perinatal Period

The association between inherited cytokine polymorphisms and cerebral palsy
Gibson CS, et al.
Am J Obstet Gynecol 2006 Mar;194(3):674.e1-11

 

Symptoms, Signs and Ill-defined Conditions

Polymorphisms of heat shock protein-70 (hspa1b and hspa1l Loci) do not influence infection or outcome risk in critically ill surgical patients
Bowers DJ, et al.
Shock 2006 Feb;25(2):117-22

 

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Page last reviewed: June 8, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics