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piperazinedione A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | compound 593A Merck Compound 593A; | | | Abbreviation: | | PZD | | | Code name: | | 593A | | |
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