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pyroxamide
A synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Chemical structure name: | | Suberoyl-3-aminopyridineamide Hydroxamic Acid | | |
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