FDA Approves New Genetic Test for Patients with Breast Cancer.
	NIH's National Human Genome Research Institute requests proposals for conducting systematic reviews of community–based family health history projects. (29 KB)

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
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Molecular genetics of lung cancer in people who have never smoked Subramanian J & Govindan R Lancet Oncol 2008 Jul;9(7):676-82

Prediction of paclitaxel resistance in breast cancer: is CYP1B1*3 a new factor of influence?
Mathias G, et al.
Pharmacogenomics 2008 Jul;9(7):969-74

Pharmacogenetics of analgesics: toward the individualization of prescription
Rollason V, et al.
Pharmacogenomics 2008 Jul;9(7):905-33

Pharmacogenetics of Crohn's disease
Torok HP, et al.
Pharmacogenomics 2008 Jul;9(7):881-93

Genetics of stroke: a review of recent advances
Domingues-Montanari S, et al.
Expert Rev Mol Diagn 2008 Jul;8(4):495-513

Apical junction complex proteins and ulcerative colitis: a focus on the PTPRS gene
Muise A & Rotin D
Expert Rev Mol Diagn 2008 Jul;8(4):465-77

Pharmacogenomics with antidepressants in the STAR*D study
Lin E & Chen PS
Pharmacogenomics 2008 Jul;9(7):935-46

Pharmacogenomics and treatment for dementia induced by Alzheimer's disease
Gupta M, et al.
Pharmacogenomics 2008 Jul;9(7):895-903

The Relationship Between Psychological Distress and Personality in Women from Families with Familial Breast/Ovarian or Hereditary Non-polyposis Colorectal Cancer in the Absence of Demonstrated Mutations
Geirdal AO & Dahl AA
J Genet Couns 2008 Jul

Clinical significance of apolipoprotein A5
Tai ES & Ordovas JM
Curr Opin Lipidol 2008 Aug;19(4):349-54

Functional genetic polymorphisms and female reproductive disorders: Part I: polycystic ovary syndrome and ovarian response
Simoni M, et al.
Hum Reprod Update 2008 Jul

Combining identity by descent and association in genetic case-control studies
Zhang Q, et al.
BMC Genet 2008 Jul;9(1):42

Genetics of Psoriasis and Psoriatic Arthritis: Update and Future Direction
Duffin KC, et al.
J Rheumatol 2008 Jul;35(7):1449-53

"What is this Genetics, Anyway?"
Shaw A & Hurst JA
J Genet Couns 2008 Jul

"I Wouldn't Classify Myself as a Patient"
Phelps C, et al.
J Genet Couns 2008 Jul

Development of sensitive and specific age- and gender-specific low-density lipoprotein cholesterol cutoffs for diagnosis of first-degree relatives with familial hypercholesterolaemia in cascade testing
Starr B, et al.
Clin Chem Lab Med 2008;46(6):791-803

Effect of Parental Coronary Artery Disease on Adverse Effects of the Metabolic Syndrome and Aging on Carotid Artery Intima-Media Thickness (from the Bogalusa Heart Study)
Chen W, et al.
Am J Cardiol 2008 Jul;102(2):180-3

 

What is the clinical utility of DNA testing in patients with familial hypercholesterolaemia?
Humphries SE, et al.
Curr Opin Lipidol 2008 Aug;19(4):362-8

Genetic Testing of Children at Risk for Adult Onset Conditions: When is Testing Indicated?
Lwiwski N, et al.
J Genet Couns 2008 Jul

Molecular diagnosis of German patients with late-onset glycogen storage disease type II
Joshi PR, et al.
J Inherit Metab Dis 2008 Jul

Novel Association of ABO Histo-Blood Group Antigen with Soluble ICAM-1: Results of a Genome-Wide Association Study of 6,578 Women
Pare G, et al.
PLoS Genet 2008 Jul;4(7):e1000118

Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms  of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis
Sarasquete ME, et al.
Blood 2008 Jul

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending July 9, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue
Certain Conditions Originating in the Perinatal Period
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page