CDC's National Office of Public Health Genomics seeks a new health scientist. For more information about this position, click on the U.S. Department of Health and Human Services website and enter the vacancy number. The deadline to apply is March 12, 2008. CDC Employees: Use HHS-CDC-T2-2008-0382 if you are a current employee. If you are a current employee who is also a medical officer, please use HHS-CDC-T1-2008-0009. Non-CDC: Use HHS-CDC-D2-2008-0136 if you are a non-federal applicant. If you are a non-federal applicant who is also a medical doctor (MD), please use HHS-CDC-D1-2008-0007.
	The National Institutes of Health (NIH) is hosting a meeting on "Translating Whole Genome Association Data into Clinical Research and Practice", March 10-11, 2008 in Bethesda, MD, as part the NIH Genes, Environment, and Health Initiative.
	NIH's National Human Genome Research Institute is sponsoring a grant for Centers of Excellence in Genomics Science to advance genome research.
	CDC is sponsoring an ASHG Genetics and Public Health Research and Practice Program fellowship to enhance CDC’s current activities and develop new approaches in integrating genetics and genomics into public health policy and programs at the national, state, and local levels. The deadline to apply is March 15, 2008.

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Sample-size properties of a case-control association analysis of multistage SNP studies for identifying disease susceptibility genes
Kitamura N, et al.
J Hum Genet 2008 Feb

Surveying germline genomic landscape of breast cancer
Hemminki K, et al.
Breast Cancer Res Treat 2008 Feb

Do polymorphisms in ABC transporter genes influence risk of childhood acute lymphoblastic leukemia?
Jamroziak K & Robak T
Leuk Res 2008 Feb

Finding gene-environment interactions for generalised anxiety disorder
Gregory AM, et al.
Eur Arch Psychiatry Clin Neurosci 2008 Feb

The pharmacogenomic era: promise for personalizing attention deficit hyperactivity disorder therapy
Stein MA & McGough JJ
Child Adolesc Psychiatr Clin N Am 2008 Apr;17(2):475-90

Gene modifiers in cystic fibrosis
Accurso FJ & Sontag MK
J Clin Invest 2008 Feb

Genetics of attention deficit hyperactivity disorder
Mick E & Faraone SV
Child Adolesc Psychiatr Clin N Am 2008 Apr;17(2):261-84

Genotype-phenotype correlations analysis of mutations in the phenylalanine hydroxylase (PAH) gene
Bercovich D, et al.
J Hum Genet 2008 Feb

 

Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia
Heshka J, et al.
J Genet Couns 2008 Feb

Role of Parenting Relationship Quality in Communicating about Maternal BRCA1/2 Genetic Test Results with Children
Demarco TA, et al.
J Genet Couns 2008 Feb

Asymptomatic individuals at genetic risk of haemochromatosis take appropriate steps to prevent disease related to iron overload
Allen KJ, et al.
Liver Int 2008 Mar;28(3):363-9

Patient-focused outcomes following detection in a hospital-based screening programme for C282Y haemochromatosis
McCullen MA, et al.
Intern Med J 2008 Feb

Developing a new generation of tests for genotyping hemophilia causative rearrangements involving int22h and int1h hotspots in the factor 8 gene
Rossetti LC, et al.
J Thromb Haemost 2008 Feb

Management of MUTYH-associated neoplasia in Australia
Worthley DL, et al.
Intern Med J 2008 Feb

 

Association of colorectal adenoma with other malignancies in Swedish families
Hiripi E, et al.
Br J Cancer 2008 Feb

Management of families at high risk for hereditary breast-ovarian cancers: The endocrinologist's point of view
Courtillot C & Touraine P
Ann Endocrinol (Paris) 2008 Feb

The Relative Accuracy of a Questionnaire Compared With Pedigree Analysis in Genetic Risk Assessment for Infertility
Danziger Kaplan K, et al.
J Urol 2008 Feb

Screen positive rates among six family history screening protocols for breast/ovarian cancer in four cohorts of women
McClain MR, et al.
Fam Cancer 2008 Feb

 

Structural genomic variation in ischemic stroke
Matarin M, et al.
Neurogenetics 2008 Feb

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending February 27, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorder
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page