New article “Genetics by Numbers”  (775KB) published in the January 31, 2008 issue of Nature. See quotes by Dr. Muin J. Khoury, director, National Office of Public Health Genomics, CDC, and other experts.
	New article “Experts Concerned as Commercial Genetic Assessments Hit the Market”  (1.19MB) published in the February 15, 2008 issue of AAPA News. See quotes by Dr. Muin J. Khoury and other experts.
	CDC is sponsoring an ASHG Genetics and Public Health Research and Practice Program fellowship to enhance CDC’s current activities and develop new approaches in integrating genetics and genomics into public health policy and programs at the national, state, and local levels. For more information, visit the American Society of Human Genetics (ASHG) website.  The deadline to apply is March 15, 2008.
	Final applications are due February 27, 2008 for CDC's National Office of Public Health Genomics funding opportunity for genomics translation research. If you have questions, please contact Brenda Colley-Gilbert at 770/488-8390 or bjc4@cdc.gov.
	HuGENet™ What's New February 2008

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Role of hereditary factors in weight loss and its maintenance
Hainer V, et al.
Physiol Res 2008 Feb

Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers
Friebel TM, et al.
Clin Breast Cancer 2007 Dec;7(11):875-82

Pharmacogenomics and therapeutics of hemoglobinopathies
Patrinos GP & Grosveld FG
Hemoglobin 2008;32(1):229-36

Late-onset neutropenia associated with rituximab therapy: evidence for a maturation arrest at the (pro)myelocyte stage of granulopoiesis
Tesfa D, et al.
Med Oncol 2008 Feb

Genetics in clinical practice: general practitioners' educational priorities in European countries
Julian-Reynier C, et al.
Genet Med 2008 Feb;10(2):107-13

Assessing educational priorities in genetics for general practitioners and specialists in five countries: factor structure of the Genetic-Educational Priorities (Gen-EP) scale
Calefato JM, et al.
Genet Med 2008 Feb;10(2):99-106

Highly cost-efficient genome-wide association studies using DNA pools and dense SNP arrays
Macgregor S, et al.
Nucleic Acids Res 2008 Feb

Evaluating cost efficiency of SNP chips in genome-wide association studies
Li C, et al.
Genet Epidemiol 2008 Feb

Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers
Hughes DJ
Fam Cancer 2008 Feb

 

Regulators weigh risks of consumer genetic tests.
Schmidt C.
Nat Biotechnol. 2008 Feb;26(2):145-6

The incidence of duplicate genetic testing
Riegert-Johnson DL, et al.
Genet Med 2008 Feb;10(2):114-6

The feasibility of online genetic testing for lung cancer susceptibility: uptake  of a web-based protocol and decision outcomes
O'Neill SC, et al.
Genet Med 2008 Feb;10(2):121-30

Carrier testing in haemophilia A and B: adult carriers' and their partners' experiences and their views on the testing of young females
Dunn NF, et al.
Haemophilia 2008 Feb

Perceptions of cancer risks and predictors of colon and endometrial cancer screening in women undergoing genetic testing for Lynch syndrome
Hadley DW, et al.
J Clin Oncol 2008 Feb;26(6):948-54

 

Scoping the family history: Assessment of Lynch syndrome (hereditary nonpolyposis colorectal cancer) in primary care settings-A primer for nurse practitioners
Maradiegue A, et al.
J Am Acad Nurse Pract 2008 Feb;20(2):76-84

Family history of depression is associated with younger age of onset in patients  with recurrent depression
Tozzi F, et al.
Psychol Med 2008 Feb:1-9

Prospective surveillance of women with a family history of breast cancer: auditing the risk threshold
Anderson E, et al.
Br J Cancer 2008 Feb;98(4):840-4

Family history as a risk factor for venous thromboembolism
Noboa S, et al.
Thromb Res 2008 Feb

Family cancer history and risk of brain tumors in children: results of the SEARCH international brain tumor study
Searles Nielsen S, et al.
Cancer Causes Control 2008 Feb

 

Genome-Wide Association Identifies a Common Variant in the Reelin Gene That Increases the Risk of Schizophrenia Only in Women
Shifman S, et al.
PLoS Genet 2008 Feb;4(2):e28

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending February 20, 2008, there are HuGE articles in the following areas:

Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Blood and Blood-Forming Organs Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page