The National Institutes of Health announces two new funding opportunities for genomics translation research. Implementation Planning Grants for Educational, Behavioral, or Social Studies for Translation of Genetic Factors in Common Diseases (U34) Translation of Common Disease Genetics into Clinical Applications (R21)
	HuGENet™ What's New August 2008

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Cancer
Beyond PTEN: Alternate genes linked to breast, thyroid and kidney cancer predisposition, Medical News Today, August 8	Researchers discover how tumor suppressor inhibits cell growth, EurekAlert, August 7
Why gene therapy caused leukemia in some "Boy In The Bubble Syndrome" patients, Medical News Today, August 8

Consumer contribution to the delivery of genetic health services Nisselle A, et al. Am J Med Genet A 2008 Aug

Neuronal nicotinic acetylcholine receptors: From the genetic analysis to neurological diseases
Steinlein OK & Bertrand D
Biochem Pharmacol 2008 Jul

U-Statistics-based Tests for Multiple Genes in Genetic Association Studies
Wei Z, et al.
Ann Hum Genet 2008 Aug

Hereditary breast cancer: From molecular pathology to tailored therapies
Tan DS, et al.
J Clin Pathol 2008 Aug

Prediction of individual genetic risk of complex disease
Wray NR, et al.
Curr Opin Genet Dev 2008 Aug

DrugBank and its relevance to pharmacogenomics
Wishart DS
Pharmacogenomics 2008 Aug;9(8):1155-62

Genetic variations associated with interindividual sensitivity in the response to arsenic exposure
Hernandez A & Marcos R
Pharmacogenomics 2008 Aug;9(8):1113-32

Pharmacogenetics in colorectal cancer: a systematic review
Funke S, et al.
Pharmacogenomics 2008 Aug;9(8):1079-99

Pharmacogenetics of etanercept in rheumatoid arthritis
Danila MI, et al.
Pharmacogenomics 2008 Aug;9(8):1011-5

The contribution of genes to osteoarthritis
Valdes AM & Spector TD
Rheum Dis Clin North Am 2008 Aug;34(3):581-603

Understanding the Nutrigenomic Definitions and Concepts at the Food-Genome Junction
Subbiah MT
OMICS 2008 Aug

Genetics of Irritable Bowel Syndrome
Saito YA & Talley NJ
Am J Gastroenterol 2008 Aug

SNP technologies for drug discovery: a current review
Voisey J & Morris CP
Curr Drug Discov Technol 2008 Aug;5(3):230-5

Impact of genetics in childhood asthma
Pinto LA, et al.
J Pediatr (Rio J) 2008 Aug;84(3 (Suppl))

An optimal dose-effect mode trend test for SNP genotype tables
Yamada R & Okada Y
Genet Epidemiol 2008 Aug

Communicating genetics research results to families: problems arising when the patient participant is deceased
Ormondroyd E, et al.
Psychooncology 2008 Aug;17(8):804-11

The Impact of Social Roles on the Experience of Men in BRCA1/2 Families: Implications for Counseling
Daly MB
J Genet Couns 2008 Aug

Statistical performance of cladistic strategies for haplotype grouping in pharmacogenetics
Lunceford JK & Liu N
Stat Med 2008 Aug

A genetic link between type 2 diabetes and prostate cancer
Frayling TM, et al.
Diabetologia 2008 Aug

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
Zanger UM, et al.
Anal Bioanal Chem 2008 Aug

Appropriate data cleaning methods for genome-wide association study
Miyagawa T, et al.
J Hum Genet 2008 Aug

Consumer contribution to the delivery of genetic health services
Nisselle A, et al.
Am J Med Genet A 2008 Aug

Healthy choices through family history: a community approach to family history awareness
Petruccio C, et al.
Community Genet 2008;11(6):343-51

Effect of Family History on Outcomes in Patients Treated with Definitive Brachytherapy for Clinically Localized Prostate Cancer
Peters CA, et al.
Int J Radiat Oncol Biol Phys 2008 Aug

Co-occurrence of celiac disease and other autoimmune diseases in celiacs and their first-degree relatives
Neuhausen SL, et al.
J Autoimmun 2008 Aug

 

Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders - updated European recommendations
Dequeker E, et al.
Eur J Hum Genet 2008 Aug

Acculturation and Familiarity With, Attitudes Towards and Beliefs about Genetic Testing for Cancer Risk Within Latinas in East Harlem, New York City
Sussner KM, et al.
J Genet Couns 2008 Aug

Adolescent Medical Providers' Willingness to Recommend Genetic Susceptibility Testing for Nicotine Addiction and Lung Cancer Risk to Adolescents
O'Neill SC, et al.
J Pediatr Psychol 2008 Aug

Hereditary diffuse gastric cancer: surgery, surveillance and unanswered questions
Cisco RM & Norton JA
Future Oncol 2008 Aug;4(4):553-9

Genetic Counseling and Testing for Common Hereditary Breast Cancer Syndromes. A Paper from the 2007 William Beaumont Hospital Symposium on Molecular Pathology
Allain DC
J Mol Diagn 2008 Aug

Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis
Hofmann S, et al.
Nat Genet 2008 Aug

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending August 13, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies

For more information on HuGE, please visit the HuGENet™ home page