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 Thursday, April 17, 2008 Volume 20   Number 16
Update banner Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genomic research on disease prevention & population health.
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blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
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 Upcoming Events

Nominations open for Art of Listening and Art of Reporting Awards by Genetic Alliance  non-gov warning icon

American College of Medical Genetics Statement on Direct-to-Consumer Genetic Testing non-gov warning icon PDF icon(122KB)

International Genomics Consortium non-gov warning icon
Genomics Announcements
 

CDC sponsored material

Upcoming Public Health Grand Rounds: Strengthening the Public Health System to Advance Genomics, on April 29, 2008, in Ann Arbor, MI. Register for the live webcastnon-gov warning icon or register to attend in personnon-gov warning icon

   
CDC sponsored material

What's New in HuGENet™
April 2008


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

How aging affects cancer risk and outcomesnon-gov warning icon Medical News Today, April 17

Mouth may tell the tale of lung damage caused by smokingnon-gov warning icon Medical News Today, April 14

Gene variants indicate opposite survival outcomes for women and men with colon cancernon-gov warning icon Medical News Today, April 16

New insights into the genetic basis of resistance to chemotherapy in children with acute leukemianon-gov warning icon EurekAlert, April 14

Biomarkers allow doctors to match therapy to patientnon-gov warning icon News-Medical.Net, April 14

Preclinical study shows CTI's brostallicin's cancer-killing ability based on genetic profilingnon-gov warning icon GEN, April 14

Discovery of small molecule that disrupts Ewing's sarcoma oncogenenon-gov warning icon News-Medical.Net, April 14

Smoking related to subset of colorectal cancers with absent DNA repair proteinsnon-gov warning icon Medical News Today, April 14

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Cardiovascular Disease

Epigenetics

Mental stress reduces blood flow to the heart in patients with gene variationnon-gov warning icon Medical News Today, April 16

Computational approaches to the role of epigenetic marks in transcription regulationnon-gov warning icon News-Medical.Net, April 13

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Ethical, Legal, and Social Issues (ELSI)

OpenHelix joins coalition for genetic fairnessnon-gov warning icon Yahoo News, April 16

May we scan your genomenon-gov warning icon Newsweek, April 12

Study: Some students confused by geneticsnon-gov warning icon Physorg.com, April 15

Groups push a genetic banknon-gov warning icon Portland Tribune, April 11

Does knowing your genetic risks lead to better healthnon-gov warning icon Los Angeles Times, April 14

Project aims to find causes of genetic diseasenon-gov warning icon The Daily Northwestern, April 11

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Family History

Parkinson's research finds different mutations in a single gene suggest that it is primarily an inherited genetic disordernon-gov warning icon Medical News Today, April 17

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Genetic Testing

Pharmacogenomics

Genome scans go deep into your DNAnon-gov warning icon Los Angeles Times, April 14

Launching a global alliance for pharmacogenomicsnon-gov warning icon NIH News, April 14

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Mental Health

Clearer day for gene therapy: New vector carries big genes linked to inherited blindnessnon-gov warning icon EurekAlert, April 15

Some kids with autism may have a genetic defect that affects the muscles,  non-gov warning iconNews-Medical.Net, April 14

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Other News

Iron deficiency causenon-gov warning icon News-Medical.Net, April 14

Geneticist Francis Collins named first recipient of Inamori ethics prize at Case Western Reservenon-gov warning icon  Medical News Today, April 11

Largest ever study of genetics of common disease just got biggernon-gov warning icon Physorg.com, April 14

Need for biopsies may be reduced by
biomarkers
non-gov warning icon Medical News Today, April 11

Your genetic rundown on a chipnon-gov warning icon Los Angeles Times, April 14

Northeastern University professor receives 1.4 million dollar NIH grant to study genetics of resistant bacterianon-gov warning icon Medical News Today, April 11

 

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Genomics in Scientific Literature
Featured Item

Identifying Host Targets for Drug Development with Knowledge from Genome-wide Studies: Lessons from HIV-AIDS
Winkler CA
Cell Host Microbe 2008 Apr;3(4):203-5

 General Articles

Mutations, structural variations, and genome-wide resequencing: where to from here in our understanding of disease and evolution?
Tabone T
Hum Mutat 2008 Apr

Variance estimation of allele-based odds ratio in the absence of Hardy-Weinberg equilibrium
Zintzaras E
Eur J Epidemiol 2008 Apr

Nutrition and breast cancer among sporadic cases and gene mutation carriers: An overview
Bissonauth V, et al.
Cancer Detect Prev 2008 Apr

Genetic polymorphisms as a risk factor for anorexia nervosa
Sulek S, et al.
Prague Med Rep 2007;108(3):215-25

Human MHC architecture and evolution: implications for disease association studies
Traherne JA
Int J Immunogenet 2008 Apr

Personalizing foods: is genotype necessary?
Fay LB & German JB
Curr Opin Biotechnol 2008 Apr

Genetics of biliary tract diseases: new insights into gallstone disease and biliary tract cancers
Hoblinger A & Lammert F
Curr Opin Gastroenterol 2008 May;24(3):363-71

Familial aggregation of gastric cancer
Sugimura H
Gan To Kagaku Ryoho 2008 Apr;35(4):551-6

Identifying Host Targets for Drug Development with Knowledge from Genome-wide Studies: Lessons from HIV-AIDS
Winkler CA
Cell Host Microbe 2008 Apr;3(4):203-5

 

 Genetic Testing

Cancer risk assessment and the genetic counseling process: using hereditary breast and ovarian cancer as an example
Prucka SK, et al.
Med Princ Pract 2008;17(3):173-89

Intention to communicate BRCA1/BRCA2 genetic test results to the family
Barsevick AM, et al.
J Fam Psychol 2008 Apr;22(2):303-12

Therapeutic consequences of thrombophilic testing
Constans J, et al.
Rev Med Interne 2008 Apr

The biochemical and clinical penetrance of individuals diagnosed with genetic haemochromatosis by predictive genetic testing
Watkins S, et al.
Eur J Gastroenterol Hepatol 2008 May;20(5):379-83

 

 Family History

A family history study of binge-eating disorder
Lilenfeld LR, et al.
Compr Psychiatry 2008 May-2008 Jun;49(3):247-54

Family history of cancer and associated risk of developing neuroendocrine tumors: a case-control study
Hassan MM, et al.
Cancer Epidemiol Biomarkers Prev 2008 Apr;17(4):959-65

Positive association of apolipoprotein B gene C7673T polymorphism with cerebral  hemorrhage with family history
Zhang L, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2008 Apr;25(2):145-9

 

 Genome-Wide Association Studies

Genome-wide association analysis identifies 20 loci that influence adult height
Weedon MN, et al.
Nat Genet 2008 Apr

Effect of Variation in CHI3L1 on Serum YKL-40 Level, Risk of Asthma, and Lung Function
Ober C, et al.
N Engl J Med 2008 Apr

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending April 16, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Symptoms, Signs, and Ill-defined Conditions
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page

 

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Page last updated: April 17, 2008 (archived document)
Content Source: National Office of Public Health Genomics