New article, Will Genomics Widen or Help Heal the Schism Between Medicine and Public Health?, published in the October 2007 issue of the American Journal of Preventive Medicine. Authors: Muin J. Khoury, MD, PhD, Marta Gwinn, MD, MPH, Wylie Burke, PhD, MD, Scott Bowen, MPH, Ron Zimmern, MA, FRCP, FFPHM.
	Join the Mid-West Community Genetics Forum on Genomics, Community and Equity: A Continuing Dialogue  presented by the University of Michigan, Center for Public Health and Community Genomics on October 12th, 2007. Forums will be held in Illinois, Iowa, Michigan, Minnesota, and Missouri.
	What's New in HuGENet™ September 2007

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan
Ionita-Laza I, et al.
Am J Hum Genet 2007 Sep;81(3):607-1

Mechanisms of Disease: the genetic basis of coronary heart disease
Kullo IJ & Ding K
Nat Clin Pract Cardiovasc Med 2007 Oct;4(10):558-69

Sulphonylurea treatment does not improve psychomotor development in children with KCNJ11 mutations causing permanent neonatal diabetes mellitus accompanied by developmental delay and epilepsy (DEND syndrome)
Sumnik Z, et al.
Diabet Med 2007 Oct;24(10):1176-8

Genetics and pharmacogenetics in heart failure
Snyder EM, et al.
Curr Heart Fail Rep 2007 Sep;4(3):139-44

Accounting for error due to misclassification of exposures in case-control studies of gene-environment interaction
Zhang L, et al.
Stat Med 2007 Sep

Nutrition in the genomics era: Cardiovascular disease risk and the Mediterranean diet
Ordovas JM, et al.
Mol Nutr Food Res 2007 Sep

PADB: Published Association Database
Rhee H & Lee JS
BMC Bioinformatics 2007 Sep;8(1):348

HLA-B*5701 clinical testing: early experience in the United States
Faruki H, et al.
Pharmacogenet Genomics 2007 Oct;17(10):857-60

Carrier screening for Gaucher disease: lessons for low-penetrance, treatable diseases
Zuckerman S, et al.
JAMA 2007 Sep;298(11):1281-90

Colorectal cancer survivors undergoing genetic testing for hereditary non-polyposis colorectal cancer: motivational factors and psychosocial functioning
Esplen M, et al.
Clin Genet 2007 Sep

 

The Impact of Truncation and Missing Family Links in Population-based Registers on Familial Risk Estimates
Leu M, et al.
Am J Epidemiol 2007 Sep

INFLUENCE OF FAMILY HISTORY OF DIABETES ON INCIDENCE AND PREVALENCE OF LATENT AUTOIMMUNE DIABETES OF THE ADULT (LADA). RESULTS FROM THE NORD-TRONDELAG HEALTH STUDY
Carlsson S, et al.
Diabetes Care 2007 Sep

Importance of familial factors in associations between offspring birth weight and parental risk of type-2 diabetes
Bergvall N, et al.
Int J Epidemiol 2007 Sep

RAD51 135G>C polymorphism and risk of familial breast cancer in a South American  population
Jara L, et al.
Cancer Genet Cytogenet 2007 Oct;178(1):65-9

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending September 26, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period
Symptoms, Signs, and Ill-defined Conditions
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page