New CDC funding opportunity "Reporting DNA-Based Genetic Test Results Applicable to Heritable Conditions and/or Markers of Drug Metabolism: The Clinical Laboratory Report as a Decision-Support Tool"
	New article on “Discriminating on Genes" published online July 4, 2007 by Nature (last accessed 2/2008)
	July public health genomics seminar presented by CDC July 26, 2007, Rockville, MD (ENVISION – Atlanta, GA) “But how do we translate new genetic knowledge into practice?"
	What's New in HuGENet™ July 2007

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Cancer
New working principle in cancer treatment, News-Medical.Net, July 5	Gene variations directly link inflammation to an increased risk for lung cancer,   EurekAlert, July 3
Genetic mutation that may alter response to cancer therapeutics found,  News-Medical.Net, July 4	Researchers study genetics, other factors to determine why black women have higher rates of aggressive breast cancer,   Medical News Today, June 28
Gene for brain cancer identified,   (last accessed 2/2008) Hindustan Times, July 3
Fat kills cancer,  EurekAlert, July 3

Genetic susceptibility to lymphoma
Skibola CF, et al.
Haematologica 2007 Jul;92(7):960-9

Human genetic factors in nonsyndromic cleft lip and palate: An update
Carinci F, et al.
Int J Pediatr Otorhinolaryngol 2007 Jun

Genetics of chronic pain states
Buskila D
Best Pract Res Clin Rheumatol 2007 Jun;21(3):535-47

ACE Genotype, Risk and Causal Relationship to Stroke: Implications for Treatment
Slowik A, et al.
Curr Treat Options Cardiovasc Med 2007 Jun;9(3):198-204

A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome
Sanchez-Cespedes M
Oncogene 2007 Jun

Antiepileptic Medication During Pregnancy: Does Fetal Genotype Affect Outcome?
Atkinson DE, et al.
Pediatr Res 2007 Jun

Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy?
Ueno H, et al.
Br J Cancer 2007 Jun

Does cystic fibrosis neonatal screening detect atypical CF forms? Extended genetic characterization and 4-year clinical follow-up
Narzi L, et al.
Clin Genet 2007 Jul;72(1):39-46

CD14, Endotoxin, and Asthma Risk: Actions and Interactions
Martinez FD
Proc Am Thorac Soc 2007 Sep;4(3):221-5

Gene-air pollution interactions in asthma
London SJ
Proc Am Thorac Soc 2007 Sep;4(3):217-20

 

Seven novel mutations and four exon deletions in a collection of Norwegian patients with SPG4 hereditary spastic paraplegia
Erichsen AK, et al.
Eur J Neurol 2007 Jul;14(7):809-14

Parental transmission of MS in a population-based Canadian cohort
Herrera BM, et al.
Neurology 2007 Jun

 

Communicating genetic information in the family: the familial relationship as the forgotten factor
Gilbar R
J Med Ethics 2007 Jul;33(7):390-3

The Role of Genetic Testing for Cancer Susceptibility in Gynecologic Practice
Karlan BY, et al.
Obstet Gynecol 2007 Jul;110(1):155-67

Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations
Nielsen M, et al.
BMC Med Genet 2007 Jul;8(1):42

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending July 4, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period

For more information on HuGE, please visit the HuGENet™ home page