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 Thursday, December 6, 2007 Volume 19   Number 22
Update banner Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
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blue dotGenomics In The News
blue dotScientific Literature
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 Upcoming Events

Public Health Genomics Institute: A Scientific Foundation for Closing the Gap Between Human Genome Discoveries and Population Health  non-gov warning icon (last accessed 2/2008)

Translating ELSI: Ethical, Legal and Social Implications of Genomics  non-gov warning icon

December Seminar Series, National Human Genome Research Institute   non-gov warning icon



 Let's Go Surfing
Family history as a risk factor for common, complex
disease, PHG Foundation
 non-gov warning icon
The Cancer Genome Atlas

Breast Cancer Risk Assessment Tool


CDC Celebrates 10 Years of Public Health Genomics - January 23, 2008
EGAPP logo U.S. Capitol
EGAPP Stakeholders Group
CDC's National Office of Public Health Genomics announces the first meeting of the Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Stakeholders Group (ESG).
> Read more
NOPHG Announces New Funding Opportunity
CDC's National Office of Public Health Genomics announces a new funding opportunity for those interested in genomics translation research.
> Read more
Genomics Announcements
   
CDC sponsored material

CDC's National Office of Public Health Genomics is looking for a new health services researcher. For more information about the position, click on the U.S. Department of Health and Human Services website non-gov warning icon and enter the vacancy number (HHS-CDC-T2-2008-0091 – for current employees or HHS-CDC-D2-2008-0054 – for non-federal applicants). The deadline to apply is January 2, 2008.

   
CDC sponsored material
New podcast, “Family History – An Early Warning for Your Child,” produced by CDC’s National Center on Birth Defects and Developmental Disabilities.


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Get to know your family history this holiday season: Be aware of prevalent cancers in your familynon-gov warning icon Newswise, December 4

Prophylactic mastectomy: Breast cancer prevention for high-risk womennon-gov warning icon Mayo Clinic, November 30

Gene BRCA1: Three sisters go in for mastectomiesnon-gov warning icon Whidbey News-Times, December 1

 

Cardiovascular Disease

Genes found that protect heart from chemonon-gov warning icon The Money Times, December 4

60 years later, landmark heart study in U.S. expanding to genetic factors behind health and diseasenon-gov warning icon International Herald Tribune, November 30

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Family History

Family health history helps identify risksnon-gov warning icon Mayo Clinic, December 5

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Genetic Testing

Tougher gene test regulation callnon-gov warning icon BBC News, December 5

Genetic tests branded a waste of moneynon-gov warning icon Guardian Unlimited, December 1

Genetic testing may help people with severe type of migraine4non-gov warning icon Medical News Today, December 4

Direct-to-consumer advertising for genetic tests concerns physicians and may mislead patientsnon-gov warning icon EurekAlert, November 30

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Mental Health

Genetic markers for mental illnessnon-gov warning icon News-Medical.Net, December 4

Researchers develop new genetic method and identify novel genes for schizophrenianon-gov warning icon Medical News Today, December 4

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Other News

Human genome pioneer and open-source junkie enters genomic X-prizenon-gov warning icon Wired, December 4

Mutant sperm guide clinicians to new diseasesnon-gov warning icon EurekAlert, December 2

Genomic disorders occur more frequently than previously thoughtnon-gov warning icon News-Medical.Net, December 3

New susceptibility gene discovered for Chronic Pancreatitis CTRC named new "bad guy" of diseasenon-gov warning icon Medical News Today, December 2

Lupus gene finding prompts call for more DNA samplesnon-gov warning icon Medical News Today, December 3

Researchers develop powerful tool to study the genetics of inflammationnon-gov warning icon EurekAlert, November 30

Blindness-causing gene mutation identified in Yemenite Jewsnon-gov warning icon (last accessed 2/2008) The Jerusalem Post, December 2

Switched-off genes may hold keys to healthnon-gov warning icon CBS News, November 30

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Genomics in Scientific Literature
Featured Item

Genetic profiling and tailored therapy in asthma: Are we there yet?
Lugogo NL, et al.
Curr Opin Mol Ther 2007 Dec;9(6):528-37

 General Articles

MutaGeneSys: Estimating Individual Disease Susceptibility Based on Genome-Wide SNP Array Data
Stoyanovich J & Pe'er I
Bioinformatics 2007 Nov

A forest-based approach to identifying gene and gene gene interactions
Chen X, et al.
Proc Natl Acad Sci U S A 2007 Nov

5-HT1A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies
Drago A, et al.
Int J Neuropsychopharmacol 2007 Nov:1-21

Genetic association with rheumatoid arthritis-Genetic Analysis Workshop 15: summary of contributions from Group 2
Wilcox MA, et al.
Genet Epidemiol 2007 Nov;31(S1):S12-S21

Effect of linkage disequilibrium between markers in linkage and association analyses
Dupuis J
Genet Epidemiol 2007 Nov;31(S1):S139-S148

Issues in association mapping with high-density SNP data and diverse family structures
Bickeboller H, et al.
Genet Epidemiol 2007 Nov;31(S1):S22-S33

Genome-wide association analyses of expression phenotypes
Chen GK, et al.
Genet Epidemiol 2007 Nov;31(S1):S7-S11

Summary of contributions to GAW15 Group 13: candidate gene association studies
de Andrade M & Allen AS
Genet Epidemiol 2007 Nov;31(S1):S110-S117

A review of current approaches to identifying human genes involved in myopia
Tang WC, et al.
Clin Exp Optom 2008 Jan;91(1):4-22

HapMap coverage for SNPs in the Japanese population
Takeuchi F, et al.
J Hum Genet 2007 Nov

CHROMSCAN: genome-wide association using a linkage disequilibrium map
Collins A & Lau W
J Hum Genet 2007 Nov

Lung cancer susceptibility: are we on our way to identifying a high-risk group?
Kiyohara C, et al.
Future Oncol 2007 Dec;3(6):617-27

Smoking behavior and related cancers: The role of CYP2A6 polymorphisms
Nakajima M
Curr Opin Mol Ther 2007 Dec;9(6):538-44

The genetic determinants of atorvastatin response
Rodrigues AC, et al.
Curr Opin Mol Ther 2007 Dec;9(6):545-53

Constitutional polymorphisms of prostate cancer: prognostic and diagnostic implications
Hahn NM, et al.
Future Oncol 2007 Dec;3(6):665-82

 

 Family History

Familial Aggregation of Hypospadias: A Cohort Study
Schnack TH, et al.
Am J Epidemiol 2007 Nov

Projecting Individualized Absolute Invasive Breast Cancer Risk in African American Women
Gail MH, et al.
J Natl Cancer Inst 2007 Nov

Risks of Subarachnoid Hemorrhage in Siblings: A Nationwide Epidemiological Study  from Sweden
Sundquist J, et al.
Neuroepidemiology 2007 Nov;29(3-4):178-84

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending December 5, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Certain Conditions Originating in the Perinatal Period
Injury and Poisoning
Symptoms, Signs, and Ill-defined Conditions

For more information on HuGE, please visit the HuGENet™ home page

 

 

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Page last reviewed: December 6, 2007 (archived document)
Content Source: National Office of Public Health Genomics