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 Thursday, March 9, 2006     Volume 16   Number 10  
Genomics & Health Weekly Update Genomics & Health Weekly Update Family History Genomics & Health Weekly Update Family History Population Research Genomics in Practice General Public
 This weekly update provides information about the impact of human genetic research on disease prevention  and public health.
Spotlight
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CDC’s 2006 National Health Promotion Conference Call for Abstracts

CDC’s 2006 National Health Promotion Conference Call for Abstracts
September 12-14, 2006 ~ Atlanta, GA
A joint conference presented by CDC’s Coordinating Center for Health Promotion (CoCHP) as related to birth defects and developmental disabilities, chronic diseases prevention and health promotion and genomics and disease prevention. Submit a genomics and public health abstract today! Abstract due date: April 7, 2006

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CDC Announcements
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ATPM-CDC Preventive Medicine and Public Health Fellowship Program This reference links to a non-governmental website
Fellows will gain leadership experience in public health practice and policy, access to state-of-the-art technology and national databases, and will train with leading experts in the field of preventive medicine and public health. ATPM Fellowships related to genomics are listed below.
Applications are due by 4/20/06
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  • Assessing the Health Impact of Advances in Genomics  
  • Assessment of Genetic Testing in Clinical and Public Health Practice
  • The Intersection of Genetic Testing, Health Communication, and Technology: Addressing the Clinical and Laboratory Interface toward achieving Public Health Benefits
 
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(March, 2006) HuGENet™ releases the first edition of the HuGENet™ Handbook of Systematic Reviews. This reference links to a non-governmental website Link here to download free  Adobe Reader (167KB) This document has extensive guidance for integrating evidence on gene-disease associations, types of systematic reviews and complete set of points to consider for conducting such reviews.

   
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Inaugural Meeting - CDC Public Health Genomics Collaboration
March 17, 2006 ~ Atlanta, Georgia
Meeting open to CDC employees/contractors only

   
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From public health emergency to public health services: the implications for evolving criteria for newborn screening panels
Grosse S. et al. Pediatrics March 2006
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Genomics In The News
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  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press and do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
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“Penn pairs chronically ill patients with medical students to create better doctors” This reference links to a non-governmental website
(March 3) EurekAlert! reports, “Can someone who suffers from a lethal genetic disease teach a pair of medical students to become better doctors? That's the goal of a unique, long-term patient-student pairing program at the University of Pennsylvania School of Medicine.”

“Insurers still banned from genetic tests” This reference links to a non-governmental website
(March 9) National Nine News reports, “The consumer watchdog has extended a ban on life insurance companies requiring customers to be genetically tested.”

“New treatment for kidney disease?” This reference links to a non-governmental website
(March 8) myDNA reports, “A study by scientists at the University of California, Santa Barbara (UCSB), suggests that drug therapy may be a new option for patients with kidney disease.”

“Invitrogen enters into chemical genetics collaboration” This reference links to a non-governmental website
(March 8) Datamonitor reports, “Invitrogen has entered into a collaboration with the US National Institutes for Health's Chemical Genomics Center.”

“Mispairs In Genetic Material Make Protein Synthesis More Efficient” This reference links to a non-governmental website
(March 8) Medical News Today reports, “The wealth of information contained in a strand of genetic material boils down to sequences of matched pairs of nucleotides that cellular machinery decodes to construct proteins.”

“Coffee good or bad for you? It depends on your genes!” This reference links to a non-governmental website
(March 8) News Medical.Net reports, “According to a new study, depending on your genes, the caffeine in coffee is either good for you or bad for you.”

“Pesticides effect on newborns” This reference links to a non-governmental website
(March 7) myDNA reports, “A new study finds that certain newborns are much more susceptible to pesticide exposure than other newborns and adults.”

“Genomics and Proteomics Sequencing as Well as Characterisation of Expressed Human Genes Create New Opportunities in the Asia Pacific Drug Discovery Market” This reference links to a non-governmental website
(March 7) Bols@mania reports, “In an environment where costs are under constant pressure, the pharmaceutical industry is under increasing strain to develop drugs that add real value.”

“Anorexia nervosa primarily a genetic disease”
(March 7) Reuters Health reports, “Genetic factors account for 56 percent of the risk of developing anorexia nervosa, according to a report in the Archives of General Psychiatry.”

“Genetic perversity: Smoking & gene avert Parkinson's” This reference links to a non-governmental website
(March 6) EurekAlert! reports, “It has long been known that smoking offers some protection against developing Parkinson's disease and now a Queensland University of Technology PhD researcher has found out part of the reason why.”

“Blood Pressure Controlling Genes Change As Children Transform Into Adults” This reference links to a non-governmental website
(March 6) Medical News Today reports, “As children transform into adults some of the genes involved in controlling their blood pressure change as well, according to a study of more than 500 pairs of twins.”

“Missing Copies Of Important Genes May Increase Risk Of Developing Diseases” This reference links to a non-governmental website
(March 6) Medical News Today reports, “New research has found that each person may be missing hundreds of thousands of base pairs or "letters" of the genetic code which can make them more at risk of different diseases.”

“Genetic background to ravages of obesity” This reference links to a non-governmental website
(March 6) News Medical.Net reports, “Why do some overweight people stay healthy (apart from possible musculo-skeletal disorders) while obesity in other individuals leads to complications like diabetes and cardiovascular disease?”

“Children compile genetic profile” This reference links to a non-governmental website
(March 5) BBC News reports, “Schoolchildren are being asked to help compile a genetic profile of the north east of England.”

“Tay-Sachs tests limits of genetic screening” This reference links to a non-governmental website
(March 5) Fort Wayne reports, “The cherry-red spots on the baby boy’s retina told a tale of genetic catastrophe: Conner Hopf, 11 months old, almost surely will not live to see his 5th birthday.”

“New genetic discovery explains 74 percent cases of age-related macular degeneration” This reference links to a non-governmental website
(March 5) EurekAlert! reports, “A new study, led by researchers at Columbia University Medical Center, pinpoints the role that two genes – Factor H and Factor B – play in the development of nearly three out of four cases of age-related macular degeneration (AMD), a devastating eye disease that affects more than 10 million people in the United States.”

“Court Allows Suits Over Genetic Screenings” This reference links to a non-governmental website
(March 4) Red Orbit reports, “Parents can sue a doctor if a genetic screening misses a severe or fatal condition that would have caused them to seek an abortion, a divided state Supreme Court ruled Friday.”

“Health Department Will Screen Infants for Genetic Disorders” This reference links to a non-governmental website
(March 3) Red Orbit reports, “The Virginia Department of Health will screen newborns for more genetic disorders.”

“Investigating A Genetic Disorder Called Microcephaly” This reference links to a non-governmental website
(March 2) Medical News Today reports, “Determining how the brain develops and functions is one of the greatest questions facing scientists today.”

“Combined, Genes And Environment Affect Health More Than They Do Alone” This reference links to a non-governmental website
(March 2) Science Daily reports, “Both nature and nurture -- genetic makeup and the environment experienced through life -- combine to influence health and well-being, Duke University Medical Center researchers and their colleagues have determined in four new studies.”

“Mapping offers cancer hope” This reference links to a non-governmental website
(March 2) myDNA reports, “Researchers recently identified the genes that predispose some individuals to prostate cancer, marking a scientific breakthrough that could help reduce the number of future deaths.”

“Studies indicate cancer is not genetic” This reference links to a non-governmental website
(March 2) WNDU News Center reports, “We’ve all heard the laundry list of what we should and shouldn't do to prevent cancer.”

“Spanish-Speaking Americans Urged to Know Their Family Health History”
(March 2) Kansas City Info Zine reports, “Calling on all Spanish-speaking Americans to "know their family history," U.S. Surgeon General Richard H. Carmona, M.D., M.P.H., announced the availability of an updated version of a free, computerized tool in Spanish, designed to help Spanish-speaking families gather their health information.”

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Genomics in Scientific Literature
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Ethical issues in predictive genetic testing: a public health perspective
Fulda KG & Lykens K
J Med Ethics 2006 Mar;32(3):143-7

Cancer screening and risk-reducing behaviors of women seeking genetic cancer risk assessment for breast and ovarian cancers
McDonald D, et al.
Oncol Nurs Forum 2006 Mar;33(2):E27-35

Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly
Olivieri F, et al.
Mech Ageing Dev 2006 Mar

Pharmacogenomic data sample collection and storage: ethical issues and policy approaches
Joly Y & Knoppers BM
Pharmacogenomics 2006 Mar;7(2):219-26

Imaging Studies and APOE Genotype in Persons at Risk for Alzheimer's Disease
Scarmeas N & Stern Y
Curr Psychiatry Rep 2006 Feb;8(1):11-7

Sodium excretion as a modulator of genetic associations with cardiovascular phenotypes in the European Project on Genes in Hypertension
Kuznetsova T, et al.
J Hypertens 2006 Feb;24(2):235-42

Stressful life events, 5-HTT genotype and risk of depression
Zammit S & Owen MJ
Br J Psychiatry 2006 Mar;188:199-201

Policy Implications of Genetic Information on Regulation under the Clean Air Act: The Case of Particulate Matter and Asthmatics
Kramer CB, et al.
Environ Health Perspect 2006 Mar;114(3):313-9

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource
Mann GJ, et al.
Breast Cancer Res 2006 Feb;8(1):R12

The OCD collaborative genetics study: Methods and sample description
Samuels JF, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Mar

From public health emergency to public health service: the implications of evolving criteria for newborn screening panels
Grosse SD, et al.
Pediatrics 2006 Mar;117(3):923-9

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer
Bosch TM, et al.
Clin Pharmacokinet 2006;45(3):253-85

Self-surveillance for genetic predisposition to cancer: behaviors and emotions
Giarelli E
Oncol Nurs Forum 2006 Mar;33(2):221-31

The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons
Craddock N, et al.
Mol Psychiatry 2006 Feb

Role of genetic analyses in cardiology: part I: mendelian diseases: cardiac channelopathies
Priori SG & Napolitano C
Circulation 2006 Feb;113(8):1130-5

FLT3 mutations in acute myeloid leukemia
Kiyoi H & Naoe T
Methods Mol Med 2006;125:189-97

           
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HuGE Published Literature
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Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending March 8, 2006, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Certain Conditions Originating in the Perinatal Period
Symptoms, Signs, and Ill-defined Conditions

For more information on HuGE, please visit the HuGENet™ home page

 
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Upcoming Events
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New this week

11th Annual Summer Institute in Statistical Genetics This reference links to a non-governmental website
June 12-30, 2006 ~ Seattle, WA
 

Systems Biology: Global Regulation Of Gene Expression
March 23-26, 2006 ~ Cold Spring Harbor, NY

   
  The Biology of Genomes This reference links to a non-governmental website (last accessed 01/2008)
May 10-14, 2006 ~ Cold Spring Harbor, NY
   
New this week
Second Congress: International Cytogenetics and Genome Society This reference links to a non-governmental website
June 25-29, 2006 ~ Canterbury, Kent, UK
   
New this week Scandinavian Institute in Statistical Genetics This reference links to a non-governmental website
July 24-28, 2006 ~ Aarhus, Denmark
   
New this week International Society of Nurses in Genetics (ISONG) 19th Annual Conference This reference links to a non-governmental website
October 7-10, 2006 ~ New Orleans, LA
   
New this week NCRI Cancer Conference This reference links to a non-governmental website
October 8-11, 2006 ~ Birmingham, UK
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Let's Go Surfing
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Public Health Genetics Unit, UK, Newsletter, March 2006 This reference links to a non-governmental website
The Public Health Genetics Unit (PHGU) of the United Kingdom (UK) aims to keep abreast of developments in molecular and clinical genetics, and in their ethical, legal, social and public health implications.

Gene Almanac This reference links to a non-governmental website
The source for timely information about genes in your life

Genes and Disease
A collection of articles compiled by NCBI that discuss genes and the diseases that they cause

 

 

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The CDC Office of Genomics and Disease Prevention makes available the above information as a public service only. Providing
this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

This reference links to a non-governmental website
 Provides link to non-governmental sites and does not necessarily represent the views of the Centers for  Disease Control and Prevention.
Page last reviewed: March 9, 2006 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics