Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search
 
     
 Thursday, February 9, 2006     Volume 16   Number 6  
Genomics & Health Weekly Update Genomics & Health Weekly Update Family History Genomics & Health Weekly Update Family History Population Research Genomics in Practice General Public
 This weekly update provides information about the impact of human genetic research on disease prevention  and public health.
Spotlight
view the current Update
Public health professional

U.S. Surgeon General's Family History Resource Packet for Health Professionals
This free, online resource packet was developed to help health professionals educate the public about the importance of family health history.

line
   
CDC Announcements
back to top
bullhorn
What's New in HuGENet™
February 2006
line
Genomics In The News
back to top
  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press and do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
featured item lightbulb image
Featured item
“Two NIH Initiatives Launch Intensive Efforts to Determine Genetic and Environmental Roots of Common Diseases”
(February 8) NIH reports, “The Department of Health and Human Services (HHS) today announced the creation of two new, closely related initiatives to speed up research on the causes of common diseases such as asthma, arthritis and Alzheimer’s disease.”

“Making Viruses Evolve Into Better Delivery Vehicles For Gene Therapy” This reference links to a non-governmental website
(February 8) Medical News Today reports, “Viruses and humans have evolved together over millions of years in a game of one-upmanship that, often as not, left humans sick or worse.”

“Scientists Sort Through 'Junk' to Unravel a Genetic Mystery” This reference links to a non-governmental website
(February 7) The New York Times reports, “In 1965, when her 10-month-old son, David, started having seizures, Joan Stokes's excitement at being a first-time mother gave way to terror.”

“Gene mutation test predicts likelihood of early menopause” This reference links to a non-governmental website
(February 7) The Guardian reports, “A test that can predict the age a woman will enter menopause, years in advance, has been developed by doctors.”

“Alzheimer disease has a genetic cause in up to 80 percent of cases” This reference links to a non-governmental website
(February 7) News Medical.net reports, “Alzheimer disease has a genetic cause in up to 80 percent of cases, according to a University of Southern California- led study of nearly 12,000 twin pairs.”

“Is high blood pressure in your genes?”
(February 6) Health Orbit reports, “Could be says U-M expert studies blood pressure genetics- and offers tips on what to do.”

“Researchers Uncover 4 Different Genetic Bird-Flu Strains” This reference links to a non-governmental website (last accessed 2/2008)
(February 6) Forbes.com reports, “Researchers have identified several different genetic strains of the avian flu virus, H5N1, in different bird populations in Southeast Asia -- any one of which could trigger a pandemic.”

“Your drug prescription is in your genes” This reference links to a non-governmental website
(February 6) Globe and Mail reports, “For years, Toronto cardiologist Peter Liu had noticed that the oldest heart drug on the market had little effect on many of his East Asian patients.”

“What causes chronic fatigue?” This reference links to a non-governmental website
(February 5) myDNA reports, “Chronic fatigue syndrome (CFS) entails more than sleepless nights.”

“Genetic Link To Alzheimer's Disease Explored: Affected Siblings Sought” This reference links to a non-governmental website
(February 5) Medical News Today reports, “Indiana University School of Medicine researchers are looking for the tie that binds families with Alzheimer's disease together.”

“Fatty acids such as those found in corn oil turn on genes that stimulate tumor growth” This reference links to a non-governmental website
(February 5) News Medical.net reports, “Omega-6 fatty acids--such as those found in corn oil--caused human prostate tumors in cell culture to grow twice as quickly as tumors to which omega-6 fats had not been added, according to a study conducted at the San Francisco VA Medical Center.”

“Genetics, lifestyles increase risk for Native Americans” This reference links to a non-governmental website
(February 3) The Green Bay Press Gazette reports, “Dan O'Loughlin of Appleton cut his foot so severely his shoe was bloodstained, yet he didn't even know he was injured.”

“Researchers show how estrogen turns genes on and off during cancer progression” This reference links to a non-governmental website
(February 2) News Medical.net reports, “A new study suggests that the hormone estrogen works in partnership with other proteins to activate or suppress gene activity in breast cancer cells.”

“60 new genes controlled by regulatory sequences” This reference links to a non-governmental website
(February 2) News Medical.net reports, “Researchers worldwide are seeking to define ancient sections of our genetic code that may soon be as important to medical science as genes.”

“Phase II clinical trial for new gene transfer drug study” This reference links to a non-governmental website
(February 2) News Medical.net reports, “As many as 8-10 million Americans have Peripheral Artery Disease (PAD), by age 70, roughly 20 percent of the population has it, and people with PAD face a six-to-seven times higher risk of heart attack or stroke.”

“Mutation in brain cells of descendants of Abraham Lincoln suggest he suffered from movement disorder” This reference links to a non-governmental website
(February 2) EurekAlert! reports, “Researchers at Johns Hopkins and the University of Minnesota have discovered a gene mutation in the descendants of Abraham Lincoln's grandparents that suggests the Civil War president himself might have also suffered from a disease that destroys nerve cells in the cerebellum-- the part of the brain that controls movement.”

line
Genomics in Scientific Literature
back to top
featured item lightbulb image
Featured item

Ethical obligations and counseling challenges in cancer genetics
Burke W & Press N
J Natl Compr Canc Netw 2006 Feb;4(2):185-91

A maximum likelihood method for studying gene-environment interactions under conditional independence of genotype and exposure
Cheng KF
Stat Med 2006 Feb 3

Genetic susceptibility to coronary artery disease: from promise to progress
Watkins H & Farrall M
Nat Rev Genet 2006 Feb

Genetic epidemiology of rheumatoid arthritis
Oliver JE, et al.
Curr Opin Rheumatol 2006 Mar;18(2):141-6

Genetic epidemiology of health disparities in allergy and clinical immunology
Barnes KC
J Allergy Clin Immunol 2006 Feb;117(2):243-54

Optimal selection of individuals for BRCA mutation testing: a comparison of available methods
James PA, et al.
J Clin Oncol 2006 Feb;24(4):707-15

Sharing BRCA1/2 test results with first-degree relatives: factors predicting who women tell
Patenaude AF, et al.
J Clin Oncol 2006 Feb;24(4):700-6

Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution?
Aguillon JC, et al.
Immunobiology 2006;211(1-2):75-84

Germ line polymorphism in metastatic progression
Hunter KW & Crawford NP
Cancer Res 2006 Feb;66(3):1251-4

Predictive genetic testing in young people for adult-onset conditions: Where is the empirical evidence?
Duncan RE & Delatycki MB
Clin Genet 2006 Jan;69(1):8-16

Human leukocyte antigen polymorphisms: variable humoral immune responses to viral vaccines
Ovsyannikova IG, et al.
Expert Rev Vaccines 2006 Feb;5(1):33-43

The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis
Warren RB & Griffiths CE
Br J Dermatol 2005 Nov;153(5):869-73

Cancer screening in older adults in an era of genomics and longevity
Greco K
Semin Oncol Nurs 2006 Feb;22(1):10-9

line
HuGE Published Literature
back to top

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending February 8, 2006, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Symptoms, Signs, and Ill-defined Conditions


For more information on HuGE, please visit the HuGENet™ home page

 
line
Upcoming Events
back to top
featured item lightbulb image
Featured item
New this week

Open door workshop: Working with the Human Genome Sequence This reference links to a non-governmental website
May 8-10, 2006 ~ Hinston, Cambridge, UK

New this week
Genes & Behavior This reference links to a non-governmental website
February 12-17, 2006 ~ Ventura, CA
   
 

International Conference on Proteomics: Bridging the Gap Between Gene Expression and Biological Function This reference links to a non-governmental website
October 11-14, 2006 ~ Luxembourg, Luxembourg

   
New this week 1st Cuban Workshop on Genomics and Community Genetics and 3rd International Workshop on Genomics Research This reference links to a non-governmental website
November 4-10, 2006 ~ Havana, Cuba
line
Let's Go Surfing
back to top
featured item lightbulb image
Featured item

National DNA Day ASHG High School Essay Contest This reference links to a non-governmental website
Sponsored by the American Society of Human Genetics (ASHG), this contest aims to challenge students to examine, question and reflect on the purposes and social implications of genetic research.

Genetic Association Information Network (GAIN) This reference links to a non-governmental website (last accessed 2/2008)
The Genetic Association Information Network (GAIN) is a public-private partnership led by the National Institutes of Health (NIH).  This initiative will take the next step in the search to understand the genetic factors influencing risk for complex diseases.

Sanger Institute This reference links to a non-governmental website
The Sanger Institute is a genome research institute primarily funded by the Wellcome Trust. Its purpose is to further the knowledge of genomes, particularly through large scale sequencing and analysis.

 

Send websites that you would like to see included in a future update to genetics@cdc.gov

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics

The CDC Office of Genomics and Disease Prevention makes available the above information as a public service only. Providing
this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

 
This reference links to a non-governmental website
 Provides link to non-governmental sites and does not necessarily represent the views of the Centers for  Disease Control and Prevention.
Page last reviewed: February 9, 2006 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics