Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search
 

HugeNet™

Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
May 8, 2008
Volume 20, No. 19

Return to Weekly Update

Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.

Infectious and Parasitic Diseases

IL12B polymorphisms are linked but not associated with Plasmodium falciparum parasitemia: a familial study in Burkina Faso
Barbier M, et al.
Genes Immun 2008 May

Genetic Basis for Adverse Events after Smallpox Vaccination
Reif DM, et al.
J Infect Dis 2008 May

Human leukocyte antigen and cytokine receptor gene polymorphisms associated with  heterogeneous immune responses to mumps viral vaccine
Ovsyannikova IG, et al.
Pediatrics 2008 May;121(5):e1091-9

MBL2 and Hepatitis C Virus Infection among Injection Drug Users
Brown EE, et al.
BMC Infect Dis 2008 May;8(1):57

 

Neoplasms

Analysis of the DPYD gene implicated in 5-fluorouracil catabolism in Chinese cancer patients
He YF, et al.
J Clin Pharm Ther 2008 Jun;33(3):307-14

The Average Cumulative Risks of Breast and Ovarian Cancer for Carriers of Mutations in BRCA1 and BRCA2 Attending Genetic Counseling Units in Spain
Milne RL, et al.
Clin Cancer Res 2008 May;14(9):2861-9

Influence of MTHFR and RFC1 Polymorphisms on Toxicities During Maintenance Chemotherapy for Childhood Acute Lymphoblastic Leukemia or Lymphoma
Shimasaki N, et al.
J Pediatr Hematol Oncol 2008 May;30(5):347-52

DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk
Bernard-Gallon D, et al.
Mol Cancer 2008 May;7(1):36

Mutations of the MYH gene do not substantially contribute to the risk of breast cancer
Beiner ME, et al.
Breast Cancer Res Treat 2008 May

Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk
Kaklamani VG, et al.
Cancer Res 2008 May;68(9):3178-84

Epigenetic-Genetic Interactions in the APC/WNT, RAS/RAF, and P53 Pathways in Colorectal Carcinoma
Suehiro Y, et al.
Clin Cancer Res 2008 May;14(9):2560-9

Polymorphisms of methionine metabolism and susceptibility to meningioma formation
Semmler A, et al.
J Neurosurg 2008 May;108(5):999-1004

Associations of Matrix Metalloproteinase-9 Protein Polymorphisms with Lymph Node  Metastasis but not Invasion of Gastric Cancer
Tang Y, et al.
Clin Cancer Res 2008 May;14(9):2870-7

Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis
Yu D, et al.
Clin Cancer Res 2008 May;14(9):2878-86

Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility
Hu Z, et al.
Clin Cancer Res 2008 May;14(9):2887-91

Genetic polymorphisms in the carbonyl reductase 3 gene CBR3 and the NAD(P)H:quinone oxidoreductase 1 gene NQO1 in patients who developed anthracycline-related congestive heart failure after childhood cancer
Blanco JG, et al.
Cancer 2008 May

Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer
Kandioler D, et al.
J Thorac Cardiovasc Surg 2008 May;135(5):1036-41

Association between polymorphisms in cell cycle genes and advanced prostate carcinoma
Kibel AS, et al.
Prostate 2008 May

Comprehensive analysis of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 loci and squamous cell cervical cancer risk
Madeleine MM, et al.
Cancer Res 2008 May;68(9):3532-9

 

Endocrine, Nutritional and Metabolic Diseases

Association of cholesteryl ester transfer protein (TaqIB) and apolipoprotein E (HhaI) gene variants with obesity
Srivastava N, et al.
Mol Cell Biochem 2008 May

Common variants near MC4R are associated with fat mass, weight and risk of obesity
Loos RJ, et al.
Nat Genet 2008 May

Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease
Zeitlin AA, et al.
Genes Immun 2008 May

A Polymorphism Within the G6PC2 Gene Is Associated with Fasting Plasma Glucose Levels
Bouatia-Naji N, et al.
Science 2008 May

 

Diseases of the Blood & Blood-Forming Organ Disorders

Noncitrus Fruits as Novel Dietary Environmental Modifiers of Iron Stores in People With or Without HFE Gene Mutations
Milward EA, et al.
Mayo Clin Proc 2008 May;83(5):543-9

MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort
Beer PA, et al.
Blood 2008 May

Polymorphisms in two genes, IL-1B and ACE, are associated with erythropoietin resistance in Korean patients on maintenance hemodialysis
Jeong KH, et al.
Exp Mol Med 2008 Apr;40(2):161-6

 

Mental Disorders

Serotonin Transporter Gene Polymorphisms and Sertraline Response in Major Depression Patients
Dogan O, et al.
Genet Test 2008 May

Association and linkage analysis of candidate genes GRP, GRPR, CRHR1, and TACR1 in panic disorder
Hodges LM, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 May

No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder
Xu X, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 May

Association between Polymorphisms in the Vesicular Monoamine Transporter 1 Gene (VMAT1/SLC18A1) on Chromosome 8p and Schizophrenia
Lohoff FW, et al.
Neuropsychobiology 2008 May;57(1-2):55-60

Association Study between Antipsychotics- Induced Restless Legs Syndrome and Polymorphisms of Dopamine D1, D2, D3, and D4 Receptor Genes in Schizophrenia
Kang SG, et al.
Neuropsychobiology 2008 May;57(1-2):49-54

5-HTTLPR and BDNF Val66Met polymorphisms and response to rTMS treatment in drug resistant depression
Bocchio-Chiavetto L, et al.
Neurosci Lett 2008 Apr

Association study between the genetic polymorphisms of glutathione-related enzymes and schizophrenia in a Japanese population
Matsuzawa D, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 Apr

Association study of the estrogen receptor alpha gene (ESR1) and childhood-onset  mood disorders
Mill J, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 Apr

Lack of association between DRD3 gene polymorphism and response to clozapine in Turkish schizoprenia patients
Barlas IO, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 Apr

A genetic association study of the FXYD domain containing ion transport regulator 6 (FXYD6) gene, encoding phosphohippolin, in susceptibility to schizophrenia in a Japanese population
Ito Y, et al.
Neurosci Lett 2008 Apr

Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with personality traits in healthy individuals
Krug A, et al.
Eur Psychiatry 2008 Apr

The PDLIM5 gene and lithium prophylaxis: An association and gene expression analysis in Sardinian patients with bipolar disorder
Squassina A, et al.
Pharmacol Res 2008 Apr

 

Diseases of the Nervous System and Sense Organs

Mannose-binding lectin haplotypes may be associated with cerebral palsy only after perinatal viral exposure
Gibson CS, et al.
Am J Obstet Gynecol 2008 May;198(5):509.e1-509.e8

Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample
Morgan AR, et al.
Am J Med Genet B Neuropsychiatr Genet 2008 May

Replication study of the insulin receptor gene in migraine with aura
Netzer C, et al.
Genomics 2008 Apr

Association of LOXL1 Gene Polymorphisms with Pseudoexfoliation in the Japanese
Ozaki M, et al.
Invest Ophthalmol Vis Sci 2008 Apr

Synergistic effect of high lactase activity genotype and galactose-1-phosphate uridyl transferase (GALT) mutations on idiopathic presenile cataract formation
Karas-Kuzelicki N, et al.
Clin Biochem 2008 Apr

Analysis of the LRRK2 Gly2385Arg variant in primary dystonia and multiple system  atrophy in Taiwan
Lu CS, et al.
Parkinsonism Relat Disord 2008 Apr

 

Diseases of the Circulatory System

The prevalence of activated protein C (APC) resistance and factor V Leiden is significantly higher in patients with retinal vein occlusion without general risk factors. Case-control study and meta-analysis
Rehak M, et al.
Thromb Haemost 2008 May;99(5):925-9

A Missense Mutation in the CHRM2 Gene Is Associated With Familial Dilated Cardiomyopathy
Zhang L, et al.
Circ Res 2008 May

Polymorphisms in the IL6 gene in Asian Indian families with premature coronary artery disease - The Indian Atherosclerosis Research Study
Maitra A, et al.
Thromb Haemost 2008 May;99(5):944-50

{alpha}-Adducin Gly460Trp Variant Increases the Risk of Stroke in Hypertensive Dutch Women
Zafarmand MH, et al.
Hypertension 2008 May

Polymorphisms in multiple genes are associated with resting heart rate in a stepwise allele-dependent manner
Wilton SB, et al.
Heart Rhythm 2008 May;5(5):694-700

Association of ADAMDEC1 haplotype with high factor VIII levels in venous thromboembolism
Berger M, et al.
Thromb Haemost 2008 May;99(5):905-8

P-selectin gene haplotypes modulate soluble P-selectin concentrations and contribute to the risk of venous thromboembolism
Ay C, et al.
Thromb Haemost 2008 May;99(5):899-904

Angiotensinogen gene polymorphism predicts hypertension, and iridological constitutional classification enhances the risk for hypertension in koreans
Cho JJ, et al.
Int J Neurosci 2008 May;118(5):635-45

 

Diseases of the Respiratory System

Olfactory receptor gene polymorphisms and nonallergic vasomotor rhinitis
Bernstein JA, et al.
J Asthma 2008 May;45(4):287-92

 

Diseases of the Digestive System

Progression of periodontal disease and interleukin-10 gene polymorphism
Cullinan MP, et al.
J Periodontal Res 2008 Jun;43(3):328-33

Role of functional polymorphisms of NRAMP1 gene for the development of Crohn's disease
Gazouli M, et al.
Inflamm Bowel Dis 2008 May

Significant association of ABCG5 604Q and ABCG8 D19H polymorphisms with gallstone disease
Kuo KK, et al.
Br J Surg 2008 May

No Role of Matrixmetalloproteinase-3 Genetic Promoter Polymorphism 1171 as a Risk Factor for Cirrhosis in Alcoholic Liver Disease
Stickel F, et al.
Alcohol Clin Exp Res 2008 Apr

Evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and isolate tooth agenesis, in a Turkish population
Vieira AR, et al.
Arch Oral Biol 2008 Apr

Association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in  children
Holla LI, et al.
Acta Odontol Scand 2008 Apr;66(2):105-12

 

Diseases of the Genitourinary System

CTLA-4 +49 A/G genotype and HLA-DRB1 polymorphisms in Turkish patients with Henoch-Schonlein purpura
Soylemezoglu O, et al.
Pediatr Nephrol 2008 May

Angiotensinogen, angiotensine converting enzyme and plasminogen activator inhibitor-1 gene polymorphism in chronic allograft dysfunction
Azarpira N, et al.
Mol Biol Rep 2008 May

Association of interleukin-4 and interleukin-1 receptor antagonist gene polymorphisms and risk of benign prostatic hyperplasia
Konwar R, et al.
Urology 2008 May;71(5):868-72

Influence of UDP-Glucuronosyltransferase Polymorphisms on Mycophenolate Mofetil-Induced Side Effects in Kidney Transplant Patients
Betonico GN, et al.
Transplant Proc 2008 Apr;40(3):708-10

 

Diseases of the Skin and Subcutaneous Tissue

Genetic susceptibility to Keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans
Brown JJ, et al.
Exp Dermatol 2008 Apr

 

Diseases of the Musculoskeletal System and Connective Tissue

Association of the CALM1 Core Promoter Polymorphism with Knee Osteoarthritis in Patients of Greek Origin
Poulou M, et al.
Genet Test 2008 May

The -670G>A polymorphism in the FAS gene promoter region influences the susceptibility to systemic sclerosis
Liakouli V, et al.
Ann Rheum Dis 2008 Apr

A Functional Polymorphism in THBS2 that Affects Alternative Splicing and MMP Binding Is Associated with Lumbar-Disc Herniation
Hirose Y, et al.
Am J Hum Genet 2008 Apr

 

Congenital Anomalies

Family-Based Association Study of the MTHFR Polymorphism C677T in Patients With Nonsyndromic Cleft Lip and Palate from Central Europe
Reutter H, et al.
Cleft Palate Craniofac J 2008 May;45(3):267-71

Association of the GABRB3 Gene With Nonsyndromic Oral Clefts
Inoue H, et al.
Cleft Palate Craniofac J 2008 May;45(3):261-6

Analysis of five single nucleotide polymorphisms in the ESR1 gene in cryptorchidism
Wang Y, et al.
Birth Defects Res A Clin Mol Teratol 2008 May

Two MTHFR polymorphisms, maternal B-vitamin intake, and CHDs
van Driel LM, et al.
Birth Defects Res A Clin Mol Teratol 2008 May

Maternal Smoking and Oral Clefts: The Role of Detoxification Pathway Genes
Lie RT, et al.
Epidemiology 2008 Apr

 

Certain Conditions Originating in the Perinatal Period

Overrepresentation of the proarrhythmic, sudden death predisposing sodium channel polymorphism S1103Y in a population-based cohort of African-American sudden infant death syndrome
Van Norstrand DW, et al.
Heart Rhythm 2008 May;5(5):712-5

 

Injury and Poisoning

Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study
Broberg K, et al.
Environ Health 2008 Apr;7(1):15

 

For more information on HuGE, please visit the HuGENet™ home page

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics

The CDC National Office of Public Health Genomics makes available the above information as a public service only.
Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

Page last reviewed: May 8, 2008 (archived document)
Content Source: National Office of Public Health Genomics