Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search
 

HugeNet™

Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
June 22, 2006
Volume 16, No. 25

Return to Weekly Update

Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a dutch population
Bosch TM, et al.
Mol Diagn Ther 2006;10(3):175-85

Distribution of killer cell immunoglobulin-like receptors genotypes in the Lebanese population
Mahfouz R, et al.
Tissue Antigens 2006 Jul;68(1):66-71

 

Neoplasms

Common variants in mismatch repair genes and risk of invasive ovarian cancer
Song H, et al.
Carcinogenesis 2006 Jun

Mismatch Repair Polymorphisms and Colorectal Polyps: hMLH1-93G>A Variant Modifies Risk Associated with Smoking
Yu JH, et al.
Am J Gastroenterol 2006 Jun;101(6):1313-9

Polymorphisms in O6-methylguanine DNA methyltransferase and endometrial cancer risk
Han J, et al.
Carcinogenesis 2006 Jun

Genetic polymorphisms of the methylenetetrahydrofolate reductase gene, plasma folate levels, and breast cancer susceptibility: a case-control study in Taiwan
Chou YC, et al.
Carcinogenesis 2006 Jun

Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk
Kohno T, et al.
Carcinogenesis 2006 Jun

Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer
Yoon KA, et al.
Carcinogenesis 2006 Jun

Inflammation-related gene polymorphisms and colorectal adenoma
Gunter MJ, et al.
Cancer Epidemiol Biomarkers Prev 2006 Jun;15(6):1126-31

Variants in the Prostate-Specific Antigen (PSA) Gene and Prostate Cancer Risk, Survival, and Circulating PSA
Severi G, et al.
Cancer Epidemiol Biomarkers Prev 2006 Jun;15(6):1142-7

Population-Based Case-Control Study of VEGF Gene Polymorphisms and Breast Cancer Risk among Chinese Women
Kataoka N, et al.
Cancer Epidemiol Biomarkers Prev 2006 Jun;15(6):1148-52

Association of Polymorphisms in the Paraoxonase 1 Gene with Breast Cancer Incidence in the CPS-II Nutrition Cohort
Stevens VL, et al.
Cancer Epidemiol Biomarkers Prev 2006 Jun;15(6):1226-8

Macrophage Inhibitory Cytokine-1 H6D Polymorphism, Prostate Cancer Risk, and Survival
Hayes VM, et al.
Cancer Epidemiol Biomarkers Prev 2006 Jun;15(6):1223-5

Associations between Catalase Phenotype and Genotype: Modification by Epidemiologic Factors
Ahn J, et al.
Cancer Epidemiol Biomarkers Prev 2006 Jun;15(6):1217-22

Variants in the HEPSIN gene are associated with prostate cancer in men of European origin
Pal P, et al.
Hum Genet 2006 Jun

MTHFR (C677T and A1298C) Polymorphisms and Risk of Sporadic Distal Colorectal Adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom)
Mitrou PN, et al.
Cancer Causes Control 2006 Aug;17(6):793-801

 

Endocrine, Nutritional and Metabolic Diseases

Association of two functional polymorphisms in the CCR5 gene with juvenile rheumatoid arthritis
Prahalad S, et al.
Genes Immun 2006 Jun

The I Allele of the Angiotensin-Converting Enzyme Gene Polymorphism may Determine an Increase in Homocysteine Levels in Fibrate-Treated Subjects
Potaczek DP, et al.
Cardiovasc Drugs Ther 2006 Jun

Polymorphisms of Estrogen-Biosynthesis Genes CYP 17 and CYP19 may influence Age at Menarche: a Genetic Association Study in Caucasian Females
Guo Y, et al.
Hum Mol Genet 2006 Jun

Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or without diabetic pedigree in Chinese
Liu L, et al.
Mol Cell Biochem 2006 Jun

Premature Menopause in Patients with BRCA1 Gene Mutation
Rzepka-Gorska I, et al.
Breast Cancer Res Treat 2006 Jun

Plasma apoAV levels are markedly elevated in severe hypertriglyceridemia and positively correlated with the APOA5 S19W polymorphism
Henneman P, et al.
Atherosclerosis 2006 Jun

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease
Saxena R, et al.
Am J Hum Genet 2006 Jul;79(1):54-61

Polymorphisms associated with apolipoprotein B levels in Greek patients with familial hypercholesterolemia
Choumerianou DM, et al.
Clin Chem Lab Med 2006;44(7):799-806

Associations of the apolipoprotein A1/C3/A4/A5 gene cluster with triglyceride and HDL cholesterol levels in women with type 2 diabetes
Qi L, et al.
Atherosclerosis 2006 Jun

 

Mental Disorders

Attention-deficit/hyperactivity disorder (ADHD) association with the DAT1 core promoter -67 T allele
Ohadi M, et al.
Brain Res 2006 Jun

Family-based study of markers at the 5'-flanking region of the human dopamine transporter gene reveals potential association with schizophrenic psychoses
Stober G, et al.
Eur Arch Psychiatry Clin Neurosci 2006 Jun

Association between Alcoholism and the Genetic Polymorphisms of the GABA(A) Receptor Genes on Chromosome 5q33-34 in Korean Population
Park CS, et al.
J Korean Med Sci 2006 Jun;21(3):533-8

Association between DRD4 Gene and Performance of Children with ADHD in a Test of Sustained Attention
Kieling C, et al.
Biol Psychiatry 2006 Jun

Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD)
Li D, et al.
Hum Mol Genet 2006 Jun

A complete genetic association scan of the 22q11 deletion region and functional evidence reveal an association between DGCR2 and schizophrenia
Shifman S, et al.
Hum Genet 2006 Jun

Association Study Between Functional Polymorphisms in the Cytochrome P450 1A2 and 2D6 Genes and Polydipsia in Schizophrenia
Matsumoto C, et al.
Neuromolecular Med 2006;8(3):381-8           

 

Diseases of the Nervous System and Sense Organs

Association of Apolipoprotein E Polymorphisms With Normal Tension Glaucoma in a Chinese Population
Lam CY, et al.
J Glaucoma 2006 Jun;15(3):218-22

Polymorphism p.402Y>H in the complement factor H protein is a risk factor for age-related macular degeneration in an Italian population
Simonelli F, et al.
Br J Ophthalmol 2006 Jun

Homocysteine serum levels and MTHFR C677T genotype in patients with Parkinson's disease, with and without levodopa therapy
Todorovic Z, et al.
J Neurol Sci 2006 Jun

Impact of Methionine Synthase Gene and Methylenetetrahydrofolate Reductase Gene Polymorphisms on the Risk of Sudden Sensorineural Hearing Loss
Gross M, et al.
Audiol Neurootol 2006 Jun;11(5):287-93

No Association Between a Functional NAD(P)H: Quinone Oxidoreductase Gene Polymorphism (Pro187Ser) and Tardive Dyskinesia
Hori H, et al.
Neuromolecular Med 2006;8(3):375-80

Psychosocial, cognitive, and motor functioning in patients with suspected Sotos syndrome: a comparison between patients with and without NSD1 gene alterations
de Boer L, et al.
Dev Med Child Neurol 2006 Jul;48(7):582-8

Postoperative pain, morphine consumption, and genetic polymorphism of IL-1beta and IL-1 receptor antagonist
Bessler H, et al.
Neurosci Lett 2006 Jun

Diseases of the Circulatory System

Coexistence of Angiotensin II Type-1 Receptor A1166C and Angiotensin-Converting Enzyme D/D Polymorphism Suggests Susceptibility for Small-Vessel-Associated Ischemic Stroke
Szolnoki Z, et al.
Neuromolecular Med 2006;8(3):353-60

Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome
Malarstig A, et al.
Thromb Res 2006 Jun

A prospective cohort study on the absolute incidence Of venous thromboembolism and arterial cardiovascular disease in asymptomatic carriers of the prothrombin 20210A mutation
Coppens M, et al.
Blood 2006 Jun

Is there a role of the Thr164Ile-beta(2)-adrenoceptor polymorphism for the outcome of chronic heart failure?
Leineweber K, et al.
Basic Res Cardiol 2006 Jun

Haplotypes of the Caspase-1 Gene, Plasma Caspase-1 Levels, and Cardiovascular Risk
Blankenberg S, et al.
Circ Res 2006 Jun

Lack of association between alpha(2B)-adrenergic receptor polymorphism and risk of restenosis following coronary angioplasty and stent implantation - preliminary report
Manolis AS, et al.
Clin Chem Lab Med 2006;44(7):807-12

Association of a polymorphism of the ACVRL1 gene with sporadic arteriovenous malformations of the central nervous system
Simon M, et al.
J Neurosurg 2006 Jun;104(6):945-9

Factor V gene A4070G mutation and the risk of cerebral veno-sinus thrombosis occurring during puerperium
Dindagur N, et al.
Thromb Res 2006 Jun

 

Diseases of the Respiratory System

Decorin and TGF-beta1 polymorphisms and development of COPD in a general population
van Diemen CC, et al.
Respir Res 2006 Jun;7(1):89

AluyMICB dimorphism within the class I region of the major histocompatibility complex is associated with asthma and airflow obstruction in the Busselton population
Hui J, et al.
Clin Exp Allergy 2006 Jun;36(6):728-34

The arginine-16 beta 2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol
Palmer CN, et al.
Thorax 2006 Jun

The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma
Hao L, et al.
Clin Exp Allergy 2006 Jun;36(6):735-41

Determination of structure and transcriptional regulation of CYSLTR1 and an association study with asthma and rhinitis
Zhang J, et al.
Pediatr Allergy Immunol 2006 Jun;17(4):242-9

ADAM33 haplotypes are associated with asthma in a large Australian population
Kedda MA, et al.
Eur J Hum Genet 2006 Jun

 

Diseases of the Digestive System

The 32-base pair deletion of the chemokine receptor 5 gene (CCR5-Delta32) is not associated with primary sclerosing cholangitis in 363 Scandinavian patients
Melum E, et al.
Tissue Antigens 2006 Jul;68(1):78-81

MMP-1 promoter gene polymorphism and susceptibility to chronic periodontitis in a Chinese population
Cao Z, et al.
Tissue Antigens 2006 Jul;68(1):38-43

Multidrug resistance 1 gene in inflammatory bowel disease: A meta-analysis
Annese V, et al.
World J Gastroenterol 2006 Jun;12(23):3636-44

Contribution of OCTN Variants Within the IBD5 Locus to Pediatric Onset Crohn's Disease
Babusukumar U, et al.
Am J Gastroenterol 2006 Jun;101(6):1354-61

Gastrointestinal Symptoms in Families of Patients with an SCN5A-Encoded Cardiac Channelopathy: Evidence of an Intestinal Channelopathy
Locke GR 3rd, et al.
Am J Gastroenterol 2006 Jun;101(6):1299-304

 

Complications of Pregnancy, Childbirth, and the Puerperium

Stillbirth and slow metabolizers of caffeine: comparison by genotypes
Bech BH, et al.
Int J Epidemiol 2006 Jun

 

Diseases of the Skin and Subcutaneous Tissue

Earlier Occurrence of Severe Alopecia Areata in HLA-DRB1*11-Positive Patients
Marques Da Costa C, et al.
Dermatology 2006;213(1):12-4

The vulvovaginal gingival syndrome: A severe subgroup of lichen planus with characteristic clinical features and a novel association with the class II HLA DQB1( *)0201 allele
Setterfield JF, et al.
J Am Acad Dermatol 2006 Jul;55(1):98-113

Systematic evaluation of association between the microsomal glutathione S-transferase 2 common variation and psoriasis vulgaris in Chinese population
Yang S, et al.
Arch Dermatol Res 2006 Jun

Transforming Growth Factor-{beta} Gene Polymorphisms in Sarcoidosis Patients With and Without Fibrosis
Kruit A, et al.
Chest 2006 Jun;129(6):1584-91

Investigation of the p.Ser278Arg polymorphism of the autoimmune regulator (AIRE) gene in alopecia areata
Pforr J, et al.
Tissue Antigens 2006 Jul;68(1):58-61

 

Diseases of the Musculoskeletal System and Connective Tissue

The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients
Yazdani-Biuki B, et al.
Arthritis Res Ther 2006 Jun;8(4):R97

T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures
Kung AW, et al.
Bone 2006 Jun

PPAR-gamma Gene Polymorphisms and Psoriatic Arthritis
Butt C, et al.
J Rheumatol 2006 Jun

Endothelial nitric oxide synthase gene polymorphisms in patients with nontraumatic femoral head osteonecrosis
Koo KH, et al.
J Orthop Res 2006 Jun

Association of CTLA-4 gene promoter polymorphisms with systemic sclerosis in Iranian population
Almasi S, et al.
Genes Immun 2006 Jun

 

For more information on HuGE, please visit the HuGENet™ home page

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics

The CDC Office of Genomics and Disease Prevention makes available the above information as a public service only.
Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

Page last reviewed: June 8, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics