Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search
 

HugeNet™

Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
August 24, 2006
Volume 17, No. 8

Return to Weekly Update

Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Prevalence of G6PD deficiency in newborns in the south of Brazil
Castro S, et al.
J Med Screen 2006;13(2):85-6

Population distribution of the functional caspase-12 allele
Kachapati K, et al.
Hum Mutat 2006 Aug;27(9):975

The high prevalence of the poor and ultrarapid metabolite alleles of CYP2D6, CYP2C9, CYP2C19, CYP3A4, and CYP3A5 in Taiwanese population
Liou YH, et al.
J Hum Genet 2006 Aug

 

Infectious and Parasitic Diseases

Association of HLA-DR, -DQ, and Vitamin D Receptor Alleles and Haplotypes with Tuberculosis in the Venda of South Africa
Lombard Z, et al.
Hum Immunol 2006 Aug;67(8):643-54

Mannose-binding lectin genotype and invasive pneumococcal infection
Moens L, et al.
Hum Immunol 2006 Aug;67(8):605-11

Variation In MICA And MICB Genes And Enhanced Susceptibility To Paucibacillary Leprosy In South India
Tosh K, et al.
Hum Mol Genet 2006 Aug

Impact of genetic variants in IL-4, IL-4 RA and IL-13 on the anti-pneumococcal antibody response
Wiertsema SP, et al.
Vaccine 2006 Aug

A promoter polymorphism in the interferon alpha-2 gene is associated with the clinical presentation of hepatitis B
Song LH, et al.
Mutat Res 2006 Aug

           

 

Neoplasms

Population-based retrieval of newborn dried blood spots for researching paediatric cancer susceptibility genes
Klotz J, et al.
Paediatr Perinat Epidemiol 2006 Sep;20(5):449-52

Polymorphisms in the glutathione S-transferase M(1), T(1), and P(1) genes and prostate cancer prognosis
Agalliu I, et al.
Prostate 2006 Aug

Dietary intake of phytoestrogens, estrogen receptor-beta polymorphisms and the risk of prostate cancer
Hedelin M, et al.
Prostate 2006 Aug

A comprehensive association study for genes in inflammation pathway provides support for their roles in prostate cancer risk in the CAPS study
Zheng SL, et al.
Prostate 2006 Aug

High Frequency of SDHB Germline Mutations in Patients with Malignant Catecholamine-Producing Paragangliomas: Implications for Genetic Testing
Brouwers FM, et al.
J Clin Endocrinol Metab 2006 Aug

E-cadherin promoter polymorphism (C-160A) and risk of recurrence in patients with superficial bladder cancer
Lin J, et al.
Clin Genet 2006 Sep;70(3):240-5

Sequence Variants in Cell Cycle Control Pathway, X-ray Exposure, and Lung Cancer Risk: A Multicenter Case-Control Study in Central Europe
Hung RJ, et al.
Cancer Res 2006 Aug;66(16):8280-6

Joint Effects of Germ-Line p53 Mutation and Sex on Cancer Risk in Li-Fraumeni Syndrome
Wu CC, et al.
Cancer Res 2006 Aug;66(16):8287-92

Prevalence and Predictors of BRCA1 and BRCA2 Mutations in a Population-Based Study of Breast Cancer in White and Black American Women Ages 35 to 64 Years
Malone KE, et al.
Cancer Res 2006 Aug;66(16):8297-308

Methylenetetrahydrofolate Reductase and Thymidylate Synthase Genotypes and Risk of Acute Graft-versus-Host Disease Following Hematopoietic Cell Transplantation for Chronic Myelogenous Leukemia
Robien K, et al.
Biol Blood Marrow Transplant 2006 Sep;12(9):973-80

Promoter polymorphisms of DNMT3B and the risk of head and neck squamous cell carcinoma in Taiwan: A case-control study
Chang KP, et al.
Oral Oncol 2006 Aug

Presence of Epidermal Growth Factor Receptor Gene T790M Mutation as a Minor Clone in Non-Small Cell Lung Cancer
Inukai M, et al.
Cancer Res 2006 Aug;66(16):7854-8

MDM2 Promoter SNP309 Is Associated with the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C
Dharel N, et al.
Clin Cancer Res 2006 Aug;12(16):4867-71

ATM variants and cancer risk in breast cancer patients from Southern Finland
Tommiska J, et al.
BMC Cancer 2006 Aug;6(1):209

CHEK2-Positive Breast Cancers in Young Polish Women
Cybulski C, et al.
Clin Cancer Res 2006 Aug;12(16):4832-5

 

Endocrine, Nutritional and Metabolic Diseases

Pro12Ala Sequence Variant of the PPARG Gene Is Associated with Postprandial Hypertriglyceridemia in Non-E3/E3 Patients with the Metabolic Syndrome
Cardona F, et al.
Clin Chem 2006 Aug

Polymorphisms of adiponectin and resistin genes in patients with obesity and anorexia nervosa
Dolinkova M, et al.
Cas Lek Cesk 2006;145(7):562-6

Aldose reductase gene is associated with diabetic macroangiopathy in Japanese Type 2 diabetic patients
Watarai A, et al.
Diabet Med 2006 Aug;23(8):894-9

The visfatin gene is associated with glucose and lipid metabolism in a Chinese population
Jian WX, et al.
Diabet Med 2006 Sep;23(9):967-73

Nutrient Intake, Weight and Leu7Pro Polymorphism in Prepro-Neuropeptide Y in Children
Karvonen MK, et al.
J Clin Endocrinol Metab 2006 Aug

Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance
Corpeleijn E, et al.
Diabet Med 2006 Aug;23(8):907-11

The apolipoprotein A-V genotype and plasma apolipoprotein A-V and triglyceride levels: prospective risk of type 2 diabetes. Results from the Northwick Park Heart Study II
Talmud PJ, et al.
Diabetologia 2006 Aug

Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy
Takane H, et al.
J Hum Genet 2006 Aug

Association between exposure to farming, allergies and genetic variation in CARD4/NOD1
Eder W, et al.
Allergy 2006 Sep;61(9):1117-24

Association between intronic SNP in urate-anion exchanger gene, SLC22A12, and serum uric acid levels in Japanese
Shima Y, et al.
Life Sci 2006 Aug

Relationship between common functional polymorphisms of the p22phox gene (-930A > G and +242C > T) and nephropathy as a result of Type 2 diabetes in a Chinese population
Lim SC, et al.
Diabet Med 2006 Sep;23(9):1037-41

Glutathione S-transferase polymorphisms may be associated with risk of oedematous severe childhood malnutrition
Marshall KG, et al.
Br J Nutr 2006 Aug;96(2):243-8

Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women
Hietala M, et al.
Hum Reprod 2006 Aug

Pro12Ala Polymorphism of the PPARG2 Gene Is Associated with Type 2 Diabetes Mellitus and Peripheral Insulin Sensitivity in a Population with a High Intake of Oleic Acid
Soriguer F, et al.
J Nutr 2006 Sep;136(9):2325-30

HDC gene polymorphisms are associated with age at natural menopause in Caucasian women
Zhang F, et al.
Biochem Biophys Res Commun 2006 Aug

Thr54 allele carriers of the Ala54Thr variant of FABP2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians
Vimaleswaran KS, et al.
Metabolism 2006 Sep;55(9):1222-6

Endothelial nitric oxide synthase G894T (Glu298Asp) polymorphism was predictive of glycemic status in a 5-year prospective study of Chinese subjects with impaired glucose tolerance
Tso AW, et al.
Metabolism 2006 Sep;55(9):1155-8

Studies of the SIM1 gene in relation to human obesity and obesity-related traits
Hung CC, et al.
Int J Obes (Lond) 2006 Aug

 

Mental Disorders

Absence of association with DAT1 polymorphism and response to methylphenidate in a sample of adults with ADHD
Mick E, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

Investigating disease susceptibility and the negative correlation of schizophrenia and rheumatoid arthritis focusing on MIF and CD14 gene polymorphisms
de la Fontaine L, et al.
Psychiatry Res 2006 Aug

Association study of polymorphisms in N-methyl-d-aspartate receptor 2B subunits (GRIN2B) gene with Korean alcoholism
Kim JH, et al.
Neurosci Res 2006 Aug

Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents
Hopfer CJ, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

Exon 3 polymorphisms of dopamine D4 receptor (DRD4) gene and attention deficit hyperactivity disorder in Chinese children
Cheuk DK, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa
Ando T, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

Dopamine system genes interaction and neurocognitive traits in patients with schizophrenia, their relatives and healthy controls from general population
Zh Nevrol Psikhiatr Im S S Korsakova 2006;106(7):57-63

Interactive Effects of the Serotonin Transporter 5-HTTLPR Polymorphism and Stressful Life Events on College Student Drinking and Drug Use
Covault J, et al.
Biol Psychiatry 2006 Aug

Association between the interleukin-1 receptor antagonist gene and negative symptom improvement during antipsychotic treatmentdagger
Mata I, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

Association of the kappa-opioid system with alcohol dependence
Xuei X, et al.
Mol Psychiatry 2006 Aug

Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism
Baghai TC, et al.
Mol Psychiatry 2006 Aug

Possible involvement of alpha-2A adrenergic receptors in attention deficit hyperactivity disorder: Radioligand binding and polymorphism studies
Deupree JD, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

Catechol-O-methyltransferase and the clinical features of psychosis
McClay JL, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

           

 

Diseases of the Nervous System and Sense Organs

Heterozygous CYP1B1 gene mutations in Spanish patients with primary open-angle glaucoma
Lopez-Garrido MP, et al.
Mol Vis 2006;12:748-55

CTLA4 Polymorphisms and Ophthalmopathy in Graves' Disease Patients: Association Study and Meta-Analysis
Han S, et al.
Hum Immunol 2006 Aug;67(8):618-26

Association between Apolipoprotein E Polymorphisms and Age-related Macular Degeneration: A HuGE Review and Meta-Analysis
Thakkinstian A, et al.
Am J Epidemiol 2006 Aug

On the discovery of the genetic association of Apolipoprotein E genotypes and common late-onset Alzheimer disease
Roses AD
J Alzheimers Dis 2006 Aug;9(3 Suppl):361-6

Association of estrogen receptor alpha gene with Alzheimer's disease: A case-control study
Monastero R, et al.
J Alzheimers Dis 2006 Aug;9(3):273-8

Polymorphisms of Fas Gene: Relationship with Alzheimer's Disease and Cognitive Decline
Chiappelli M, et al.
Dement Geriatr Cogn Disord 2006 Aug;22(4):296-300

Genetic evidence for ubiquitin-specific proteases USP24 and USP40 as candidate genes for late-onset Parkinson disease
Li Y, et al.
Hum Mutat 2006 Aug

Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
James SJ, et al.
Am J Med Genet B Neuropsychiatr Genet 2006 Aug

 

Diseases of the Circulatory System

The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study
Fan M, et al.
Am Heart J 2006 Sep;152(3):538-42

The Versican Gene and the Risk of Intracranial Aneurysms
Ruigrok YM, et al.
Stroke 2006 Aug

The Effect of Angiotensin II Type-1 Receptor Gene Polymorphisms on Doppler Blood Flow Parameters of Carotid and Brachial Arteries in Patients with Myocardial Infarction
Ozturk O, et al.
Echocardiography 2006 Aug;23(7):536-41

The androgen receptor gene CAG repeat polymorphism does not predict increased risk of heart disease: longitudinal results from the Massachusetts Male Ageing Study
Page ST, et al.
Clin Endocrinol (Oxf) 2006 Sep;65(3):333-9

Inherited thrombophilia is associated with deep vein thrombosis in a Colombian population
Torres JD, et al.
Am J Hematol 2006 Aug

Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: Effect of ecNOS polymorphism on left ventricular hypertrophy
Olcay A, et al.
Cardiovasc Ultrasound 2006 Aug;4(1):33

Thrombospondin-4 1186G>C (A387P) is a sex-dependent risk factor for myocardial infarction: A large replication study with increased sample size from the same population
Cui J, et al.
Am Heart J 2006 Sep;152(3):543.e1-5

 

Diseases of the Respiratory System

Association between a TGFbeta1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients
Kim SH, et al.
Respir Med 2006 Aug

 

Diseases of the Digestive System

HLA DQA1*0501 and DQB1*02 in Cuban Celiac Patients
Cintado A, et al.
Hum Immunol 2006 Aug;67(8):639-42

Therapeutic effects of 10 mg/day rabeprazole administration on reflux esophagitis was not influenced by the CYP2C19 polymorphism
Ariizumi K, et al.
J Gastroenterol Hepatol 2006 Sep;21(9):1428-34

CARD15 in inflammatory bowel disease and Crohn's disease phenotypes: An association study and pooled analysis
Oostenbrug LE, et al.
Dig Liver Dis 2006 Aug

No correlation of five gene polymorphisms with periodontal conditions in a Greek population
Sakellari D, et al.
J Clin Periodontol 2006 Aug

Polymorphism in L-selectin, e-selectin and icam-1 genes in asian Indian pediatric patients with celiac disease
Kaur G, et al.
Hum Immunol 2006 Aug;67(8):634-8

Polymorphisms in the promoter region of the angiotensinogen gene are associated with liver cirrhosis in patients with chronic hepatitis B
Xiao F, et al.
J Gastroenterol Hepatol 2006 Sep;21(9):1488-91

Effect of CYP2C19*17 gene variant on Helicobacter pylori eradication in peptic ulcer patients
Kurzawski M, et al.
Eur J Clin Pharmacol 2006 Aug

Adulthood-onset celiac disease is associated with intercellular adhesion molecule-1 (icam-1) gene polymorphism
Abel M, et al.
Hum Immunol 2006 Aug;67(8):612-7

 

Diseases of the Genitourinary System

Polymorphisms in Exons 1B and 1C of the Type I Interleukin-1 Receptor Gene in Patients with Endometriosis
D'Amora P, et al.
Am J Reprod Immunol 2006 Sep;56(3):178-84

Progesterone receptor polymorphism +331G/A is associated with a decreased risk of deep infiltrating endometriosis
van Kaam KJ, et al.
Hum Reprod 2006 Aug

 

Complications of Pregnancy, Childbirth, and the Puerperium

Evidence for an association between mannose-binding lectin 2 (MBL2) gene polymorphisms and pre-term birth
Bodamer OA, et al.
Genet Med 2006 Aug;8(8):518-24

Endothelial nitric oxide synthase gene influences the risk of pre-eclampsia, the recurrence of negative pregnancy events, and the maternal-fetal flow
Fatini C, et al.
J Hypertens 2006 Sep;24(9):1823-9

 

Diseases of the Skin and Subcutaneous Tissue

MHC haplotypic association in Chinese Han patients with vitiligo
Xia Q, et al.
J Eur Acad Dermatol Venereol 2006 Sep;20(8):941-6

 

Diseases of the Musculoskeletal System and Connective Tissue

Replication of association of IL1 gene complex members with ankylosing spondylitis in Taiwanese Chinese
Chou CT, et al.
Ann Rheum Dis 2006 Aug;65(8):1106-9

MHC2TA promoter polymorphism (-168*G/A, rs3087456) is not associated with susceptibility to rheumatoid arthritis in British Caucasian rheumatoid arthritis patients
Harrison P, et al.
Rheumatology (Oxford) 2006 Aug

 

Certain Conditions Originating in the Perinatal Period

Association of sudden infant death syndrome with VEGF and IL-6 gene polymorphisms
Dashash M, et al.
Hum Immunol 2006 Aug;67(8):627-33

Interactions between fetal HLA-DQ alleles and maternal smoking influence birthweight
Taylor GM, et al.
Paediatr Perinat Epidemiol 2006 Sep;20(5):438-48

 

Injury and Poisoning

ACE I/D gene polymorphism and aerobic endurance development in response to training in a non-elite female cohort
Cam S, et al.
Scand J Med Sci Sports 2006 Aug

The role of insertion allele of Angiotensin converting enzyme gene in higher endurance efficiency and some aspects of pathophysiological and drug effects
Dekany M, et al.
Curr Med Chem 2006;13(18):2119-26

 

For more information on HuGE, please visit the HuGENet™ home page

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics

The CDC National Office of Public Health Genomics makes available the above information as a public service only.
Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

Page last reviewed: June 8, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics