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arzoxifene hydrochloride
The hydrochloride salt of arzoxifene, a synthetic aromatic derivative with anti-estrogenic properties. Arzoxifene binds to estrogen receptors as a mixed estrogen agonist/antagonist. In comparison to other selective estrogen receptor modulators (SERMs), arzoxifene exhibits greater bioavailability and higher anti-estrogenic potency in the breast than raloxifene; it exhibits reduced estrogenicity in the uterus compared with either tamoxifen or raloxifene. This agent may have beneficial effects on bone and the cardiovascular system. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | LY353381 Hydrochloride
SERM-3 | | | | Code name: | | LY353381.HCl | | | | Chemical structure name: | | 2-(4-methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]benzo[b]thiophene-6-ol hydrochloride | | |
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