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MUC-1 antigen MUC-1 antigen is a mammary-type apomucin, a high molecular weight transmembrane glycoprotein, of which the extracellular domain is formed by a repeating 20 amino acid sequence (in tandem) with a high content of serine and threonine on which are O-linked carbohydrate chains. MUC-1 synthesis and secretion are features of glandular epithelial tissues; MUC-1 is overexpressed in lactating breast and in breast, ovary, lung, and prostate malignancies. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | CA15-3 Antigen Cancer Antigen 15-3 DF3 Antigen Episialin Glycosylated MUC-1 ImMucin MUC-1 Muc1 Mucin Mucin Peptide MUC-1 Polymorphic Epithelial Mucin | | |
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