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| Thursday, March 8, 2007 |
Volume
18 Number 10 |
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| This weekly update provides information about the impact of human genetic research on disease prevention and public health. |
 Get email updates |
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Colorectal cancer is the second leading cause of death from cancer in the United States. Family history can help identify individuals at increased risk of colorectal cancer, which could prompt earlier and more frequent screening and monitoring. Read more
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March Seminar presented by CDC National Office of Public Health Genomics
What is the role of behavioral and social sciences in translating genetic research into population health benefits?
March 12, 2007, Rockville, MD (ENVISION - Atlanta, GA)
Topics to be covered:
- Beyond nature/nurture: transdisciplinary approach to genomic, behavioral and social science research
Speaker: David Abrams, Director, NIH OBSSR
- Using genomics to change health behavior
Speaker: Colleen McBride, NHGRI
This monthly seminar series (Public Health Genomics: "Closing the Gap Between Human Genome Discoveries and Population Health") explores various topics on the intersection of genomics, medicine, and public health. It is sponsored by the National Cancer Institute, National Human Genome Research Institute, National Institute for Child Health and Development, and the Office of Behavioral and Social Sciences Research. |
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CDC request for applications on Improving Public Health Practice through Translation Research (R18)
(last accessed 2/2008)
The purpose of the RFA is the achievement of new scientific knowledge that can accelerate the translation of research findings into public health practice through implementation, dissemination, and diffusion research. Components are included from various CDC offices and centers. Genomics translation research priorities include family history, genetic testing, and genetics for early disease detection and intervention. |
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The CDC Grants for Public Health Research Dissertation (R36)
The purpose of this CDC Funding Opportunity Announcement (FOA) is to invite applications for support of public health dissertation research. This program supports research undertaken as part of an academic program to qualify for a doctorate. CDC has developed the Guide to Public Health Research Needs that can be used to identify research priorities and support CDC’s Health Protection Goals. |
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- The following are headlines from on-line news articles published during the past week.
- The headlines and lead sentence are exactly as they appear in the popular press and do not necessarily reflect the opinions or recommendations of CDC.
- Free registration required for some articles.
Featured item |
No Featured Item this week. |
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“Anorexia Nervosa may be genetic: scientists” 
(last accessed 2/2008)
(Mar 7) NDTV.com reports, “Anorexia Nervosa, an eating disorder where a person starves to change her body image and become very thin, is on a rise in India.”
“Drivers and passengers on the road to cancer”
(Mar 7) EurekAlert! reports, “Scientists at the Wellcome Trust Sanger Institute, where one-third of the human genome was sequenced, have now pioneered decoding the sequence of cancer genomes.”
“Major gene study uncovers secrets of leukemia”
(Mar 7) EurekAlert! reports, “St. Jude study scans 350,000 locations across the genome from 242 patients and identifies new mutations that contribute to acute lymphoblastic leukemia, suggesting new targets for improved therapy.”
“Genetic conditions often lead to insurance refusal”
(last accessed 2/2008)
(Mar 6) Reuters Health reports, “People with sickle cell disease or cystic fibrosis—two genetic disorders—are twice as likely to be denied health insurance coverage compared with those with other chronic illnesses, according to the results of a survey.”
“Potential genetic testing for substance abuse raises hope, concern”
(Mar 6) EurekAlert! reports, “Genetic tests using blood samples already are used to diagnose some diseases and even personalize treatment.“
“Gene defect leads to an AIDS drug”
(Mar 5) boston.com News reports, “In 1996, scientists solved a mystery surrounding certain gay men who were immune to AIDS.”
“New genetic causes of facial clefts identified”
(last accessed 2/2008)
(Mar 5) Yahoo! News reports, “Researchers studying the causes of facial clefts have identified a handful of new genetic mutations linked to these birth defects in a step that might help lead to a test to predict a family's risk.”
“Study examines genetic risk factors for Alzheimer's disease”
(Mar 5) EurekAlert! reports, “Cardiff University researchers have found evidence for new genes involved in the development of Alzheimer’s disease. “
“Type 1 diabetes genetic risk much higher than previous estimates”
(Mar 5) eMaxHealth reports, “A discovery at the Barbara Davis Center for Childhood Diabetes has identified a genetic risk for type 1 diabetes three to four times higher than previously thought possible.”
“University of Bristol to create new medical research centre”
(Mar 4) News-Medical.Net reports, “The University of Bristol has been awarded £2.7 million by the Medical Research Council (MRC) to create a new research centre which will apply knowledge from genetic analyses to large-scale studies of the health of the population.”
“Researchers find the mechanism by which cells resist chemotherapy”
(Mar 2) EurekAlert! reports, “In his paper, to be published in The EMBO Journall, Dr Surrallés describes how proteins of the Fanconi/BRCA pathway recognise the presence of genetic mutations in order to repair them.”
“2007 ACMG Annual Clinical Genetics meeting - there is still time to register”
(Mar 1) Medical News Today reports, “Are you a professional in medical and clinical genetics providing comprehensive diagnostic, management or genetic counseling services for patients with, or at risk for, genetically influenced health problems?”
“Mapping disease: microarrays super-power genetic content analysis”
(last accessed 2/2008)
(Mar 1) EContent reports, “New DNA microarrays that can profile more than 500,000 exact genetic variations are giving researchers a better view of the genetic causes of many illnesses and helping them work towards more personalized treatments.”
“Single genetic defect causes early heart disease”
(Mar 1) EurekAlert! reports, “A team of researchers from the United States and Iran has identified a genetic mutation that causes early onset coronary artery disease in members of a large Iranian family.”
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Genetic contributions to Type 2 diabetes: recent insights
Sale MM & Rich SS
Expert Rev Mol Diagn 2007 Mar;7(2):207-17
The effect of HapMap on cardiovascular research and clinical practice
Skelding KA, et al.
Nat Clin Pract Cardiovasc Med 2007 Mar;4(3):136-42
Phenotypic and genetic complexity of psychosis: Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles
Craddock N, et al.
Br J Psychiatry 2007 Mar;190:200-3
Schizophrenia: a common disease caused by multiple rare alleles
McClellan JM, et al.
Br J Psychiatry 2007 Mar;190:194-9
The Role of Genetics in the Provision of Essential Public Health Services
Wang G & Watts C
Am J Public Health 2007 Feb
A review of genetic causes of ischemic and hemorrhagic stroke
Tonk M & Haan J
J Neurol Sci 2007 Feb
The effect of non-additive genetic interactions on selection in multi-locus genetic models
Hallander J & Waldmann P
Heredity 2007 Feb
Analysis of phenotype-genotype connection: the story of dissecting disease pathogenesis in genomic era in China, and beyond
Shen Y, et al.
Philos Trans R Soc Lond B Biol Sci 2007 Feb
Knowledge about genetics among african americans
Kessler L, et al.
J Genet Couns 2007 Apr;16(2):191-200
Probability biases in genetic problem solving: a comparison of undergraduates, genetic counseling graduate students, and genetic counselors
Dewhurst ME, et al.
J Genet Couns 2007 Apr;16(2):157-70
BRCA1 and BRCA2 status in a Central Sudanese series of breast cancer patients: interactions with genetic, ethnic and reproductive factors
Awadelkarim KD, et al.
Breast Cancer Res Treat 2007 Mar
Polymorphism of selected enzymes involved in detoxification and biotransformation in relation to lung cancer
Gresner P, et al.
Lung Cancer 2007 Mar
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“Blood tests may be possible for mental health conditions”
(Mar 6) EurekAlert! reports, “Blood tests for panic disorder and other mental health conditions are potentially around the corner, based on results from a University of Iowa study.”
“DVT victim’s family wants babies tested for ‘killer’ gene”
(Mar 6) The Herald reports, “The family of a student who died from deep vein thrombosis are calling for a blood test to be made available to spot those at risk of the potentially fatal condition.”
“Gene tests and brain imaging reveal early dementia”
(Mar 6) News-Medical.Net reports, “Dementia diseases develop insidiously and are generally discovered when the memory has already started to deteriorate.”
“Genetic analysis enables personalizing of treatment of cancer”
(Mar 6) Science Daily reports, "Genetic analysis has enabled the personalizing of the pharmaceutical treatment of patients with cancer, enhancing thereby therapeutic efficacy and minimizing possible toxicity.”
“Gene test helps to diagnose lung cancer early”
(Mar 05) Medical News Today reports, “US scientists have developed a genetic test to predict early stages of lung cancer by looking for genetic changes in the cells of a smoker's airways.”
“Insurers cautious about genetic tests”
(last accessed 2/2008)
(Mar 4) Sympatico msn News reports, “Some Canadians are paying high rates for critical illness insurance because the sellers aren't taking into consideration genetic tests that show the client's risk is reduced.”
“Toward genetically guided cancer treatment: gene expression test reveals critical characteristics of breast tumors”
(Mar 1) Science Daily reports, “Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online.”
| In The Scientific Literature |
Prevalence of duplications and deletions of the 22q11 DiGeorge syndrome region in a population-based sample of infants with cleft palate
Sivertsen A, et al.
Am J Med Genet A 2007 Jan;143(2):129-34
A randomized controlled trial of a decision aid for women considering genetic testing for breast and ovarian cancer risk
Wakefield CE, et al.
Breast Cancer Res Treat 2007 Feb
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Click here for more information about upcoming events.
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Genomics Disorders 2007
March 21-23, 2007 ~ Hinxton, UK |
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2007 Annual Clinical Genetics Meeting
March 21-25, 2007 ~ Nashville, TN |
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microRNA
March 29-30, 2007 ~ Boston, MA |
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17th European Congress of Clinical Microbiology and Infectious Diseases
March 31 – April 3, 2007 ~ Munich, Germany |
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UNC Conference on Pharmacogenomics
May 18-19, 2007 ~ Chapel Hill, NC |
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The Centre for Applied Genomics
The Centre for Applied Genomics (TCAG) provides genomics infrastructure to facilitate a wide variety of research, including human genomics and disease, model organisms, and agricultural and food sciences.
National DNA Day – April 25, 2007
National DNA Day commemorates the completion of the Human Genome Project in April 2003, and the discovery of DNA's double helix, with activities aimed at inspiring the next generation of scientists who will use the human genome sequence to benefit human health.
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The CDC National Office of Public Health Genomics makes available the above information as a public service only. Providing
this information does not constitute endorsement by the CDC. Note that some links may become invalid over time. |
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Provides link to non-governmental sites and does not necessarily represent the views of the Centers for Disease Control and Prevention. |
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