The vertical stacked column graph presents BLA and NDA manufacturing supplements for FY 2001 through FY 2005. The scale is in increments of 500 with a ceiling of 3,000. It indicates that during FY 2001 the number of NDA manufacturing supplements was less than 1,500. In FY 2002 the number increased to nearly 1,800, but decreased to close to 1,700 in FY 2003, close to 1,600 in FY 2004, then rose in FY 2005 to over 1,650. The number of BLA manufacturing supplements increased from just below 600 in FY 2001, to over 700 in FY 2002, and then to slightly over 900 in FY 2003. During FY 2004 the number dropped well under 900 and dropped again in FY 2005 to less than 850.