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aminothiadiazole A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20090511124241im_/http://www.cancer.gov/images/spacer.gif) | 2-Aminothiadiazole Amino 134-Thiadiazole | | ![](https://webarchive.library.unt.edu/eot2008/20090511124241im_/http://www.cancer.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/eot2008/20090511124241im_/http://www.cancer.gov/images/spacer.gif) | A-TD ATDA | | ![](https://webarchive.library.unt.edu/eot2008/20090511124241im_/http://www.cancer.gov/images/spacer.gif) | Code name: | ![](https://webarchive.library.unt.edu/eot2008/20090511124241im_/http://www.cancer.gov/images/spacer.gif) | FDA 0084 | | ![](https://webarchive.library.unt.edu/eot2008/20090511124241im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure names: | ![](https://webarchive.library.unt.edu/eot2008/20090511124241im_/http://www.cancer.gov/images/spacer.gif) | - 1,3, 4-Thiadiazol-2-amine (9CI)
- 1,3, 4-Thiadiazole, 2-Amino- (8CI)
- 1,3,4-Thiadiazole, 2-Amino
- 2-Amino-1,3,4-thiadiazole
- 2-Amino-1-thia-3,4-diazole
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