Definition of ISIS 2503 - National Cancer Institute Drug Dictionary

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ISIS 2503
A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the oncogene H-Ras. ISIS 2503 selectively inhibits the expression of H-Ras, and may inhibit the growth of some Ras-dependent tumor cells. Check for or using this agent. ()

Synonym:		H-RAS Antisense

Code name:		ISIS-2503

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Next:	ISIS 3521, ISIS 5132, isoniazid, isosulfan blue, isotretinoin