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zolpidem tartrate The tartrate salt of an imidazopyridine with non-benzodiazepine benzodiazepine-receptor agonist and sedative-hypnotic activities. Zolpidem binds selectively to the alpha 1 subunit of the omega-1 (BZ1) receptor of the gamma-aminobutyric acid type A (GABA-A ) receptor-chloride ionophore complex, thereby opening neuronal chloride channels, hyperpolarizing neuronal cell membranes, and inhibiting neuronal firing. In contrast, benzodiazepines non-selectively bind to and activate all omega receptor subtypes, exhibiting anticonvulsant and myorelaxant activities in addition to a sedative-hypnotic activity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20081024153454im_/http://www.cancer.gov/images/spacer.gif) | Ambien | | ![](https://webarchive.library.unt.edu/eot2008/20081024153454im_/http://www.cancer.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20081024153454im_/http://www.cancer.gov/images/spacer.gif) | ZPD | | ![](https://webarchive.library.unt.edu/eot2008/20081024153454im_/http://www.cancer.gov/images/spacer.gif) |
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