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medroxyprogesterone
A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | medroxyprogesterone acetate | | | | US brand names: | | Curretab
Depo-Provera
Provera
Provera Dosepak | | | | Abbreviation: | | MPA | | | | Chemical structure names: | | - (6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione
- 17alpha-hydroxy-6alpha-methylprogesterone
- 6alpha-methyl-17alpha-hydroxyprogesterone
- 6alpha-methyl-4-pregnen-17alpha-ol-3,20-dione
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