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dexverapamil The R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. This agent exhibits decreased calcium antagonistic activity and toxicity compared to racemic verapamil. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20081024104752im_/http://www.cancer.gov/images/spacer.gif) | R verapamil R-verapamil R-Verapamil Hydrochloride | | ![](https://webarchive.library.unt.edu/eot2008/20081024104752im_/http://www.cancer.gov/images/spacer.gif) |
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