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CI-921 A synthetic derivative of acridine carboxamide with antineoplastic properties. CI-921, a lipophilic and water-soluble analog of amsacrine, inhibits the enzyme topoisomerase ll, thereby blocking DNA replication and RNA and protein synthesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20081025020353im_/http://www.cancer.gov/images/spacer.gif) | Amsalog | | ![](https://webarchive.library.unt.edu/eot2008/20081025020353im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure name: | ![](https://webarchive.library.unt.edu/eot2008/20081025020353im_/http://www.cancer.gov/images/spacer.gif) | 4-Acridinecarboxamide,9-((2-methoxy-4-((methylsulfonyl)amino)phenyl)amino-N,5-dimethyl | | ![](https://webarchive.library.unt.edu/eot2008/20081025020353im_/http://www.cancer.gov/images/spacer.gif) |
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