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bromodeoxyuridine A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks (DSBs). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20081024085744im_/http://www.cancer.gov/images/spacer.gif) | 5-bromodeoxyuridine broxuridine | | ![](https://webarchive.library.unt.edu/eot2008/20081024085744im_/http://www.cancer.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/eot2008/20081024085744im_/http://www.cancer.gov/images/spacer.gif) | 5-BrdU BrdU | | ![](https://webarchive.library.unt.edu/eot2008/20081024085744im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure name: | ![](https://webarchive.library.unt.edu/eot2008/20081024085744im_/http://www.cancer.gov/images/spacer.gif) | 5-bromouracil-2-deoxyriboside | | ![](https://webarchive.library.unt.edu/eot2008/20081024085744im_/http://www.cancer.gov/images/spacer.gif) |
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