Projects

EPIDEMIOLOGY, PATHOGENESIS, AND COUNTERMEASURES TO PREVENT AND CONTROL AVIAN METAPNEUMOVIRUS INFECTION Appropriated (D)   Accession Number: 412803

Publications

Pathogenic assessment of recombinant avian metapneumovirus subgroup C viruses in SPF chickens and turkeys. - (Abstract)

Yu, Q., Estevez, C. N., King, D. J., Kapczynski, D. R., Zsak, L. 2008. Pathogenic assessment of recombinant avian metapneumovirus subgroup C viruses in SPF chickens and turkeys [abstract]. In: Abstracts of the 14th International Congress of Virology, Istanbul, Turkey. p. 318.

Generation of recombinant avian metapneumovirus subgroup C viruses for pathogenesis studies and vaccine development - (Abstract)

Yu, Q., Estevez, C. N., King, D. J., Kapczynski, D. R., Zsak, L. 2008. Generation of recombinant avian metapneumovirus subgroup C viruses for pathogenesis studies and vaccine development [abstract]. In: Proceedings of the 27th Annual Meeting of American Society for Virology, Cornell, New York. p. 296.

The role of antigenic composition of Newcastle disease (ND) vaccines in ND control - (Abstract)

Miller, P.J., Estevez, C., Yu, Q., Suarez, D.L., King, D.J. 2008. The role of antigenic composition of Newcastle disease (ND) vaccines in ND control [abstract]. In: Proceedings of the American Association of Avian Pathologists annual meeting, July 19-23, 2008, New Orleans, Louisiana. p. 65.

Glycoprotein gene truncation in avian metapneumovirus subtype C isolates from the United States - (Peer Reviewed Journal)

Velayudhan, B. T., Yu, Q., Nagaraja, K. V., Estevez, C. N., Halvorson, D. A. 2008. Glycoprotein gene truncation in avian metapneumovirus subtype C isolates from the United States. Virus Genes. 37(2):266-72.

Construction of a fowl adenovirus recombinant to express avian metapneumovirus glycoprotein - (Abstract) - (19-Dec-07)

Research update on exotic and emerging poultry diseases - (Proceedings/Symposium)

Pantin Jackwood, M.J., Suarez, D.L., Zsak, L., Spackman, E., Kapczynski, D.R., King, D.J., Afonso, C.L., Day, J.M., Spatz, S.J., Yu, Q., Swayne, D.E. 2007. Research update on exotic and emerging poultry diseases. In: Proceedings of the 111th Annual Meeting of the U. S. Animal Health Association, Reno, Nevada, October 22-23, 2007. p. 702-707. Available: http://www.usaha.org/meetings/2007/2007_USAHA_Proceedings.pdf.

Rescue of recombinant avian metapneumovirus subgroup C viruses from cloned DNAs for vaccine development and pathogenesis studies - (Proceedings/Symposium)

Yu, Q., Estevez, C., King, D.J., Kapczynski, D.R., Zsak, L. 2007. Rescue of recombinant avian metapneumovirus subgroup C viruses from cloned DNAs for vaccine development and pathogenesis studies. In: Proceedings of 2007 Turkey Research Review and Avian Pneumovirus Symposium, September 26-27, 2007 Willmar, Minnesota. 2007 CDROM.

Evaluation of different hemagglutinin-neuraminidase and fusion protein chimeras using a reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain - (Proceedings/Symposium)

Estevez, C., King, D.J., Miller, P.J., Yu, Q. 2007. Evaluation of different hemagglutinin-neuraminidase and fusion protein chimeras using a reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain. In: The 15th World Poultry Veterinarian Association Abstract Book, September 10-15, 2007, Beijing, China. p. 153.

Evaluation of Newcastle disease virus chimeras expressing the hemagglutinin-neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone - (Peer Reviewed Journal)

Estevez, C., Yu, Q., King, D.J., Seal, B.S. 2007. Evaluation of Newcastle disease virus chimeras expressing the hemagglutinin-neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone. Virus Research. 129:182-190.

A Newcastle disease virus hemagglutinin-neuraminidase mutation that diminished hemagglutination and neuraminidase activity did not change infectivity and pathogenecity - (Abstract)

Yu, Q., Estevez, C., King, D.J., Miller, P.J. 2007. A Newcastle disease virus hemagglutinin-neuraminidase mutation that diminished hemagglutination and neuraminidase activity did not change infectivity and pathogenecity [abstract]. In: Proceedings of the 26th Annual Meeting of American Society for Virology, July 14-18, 2007, Corvallis, Oregon. p. 106.

Evaluation of different hemagglutinin-neuraminidase (HN) chimeras using a newly developed reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain - (Abstract)

Estevez, C., Yu, Q., King, D.J., Miller, P.J. 2007. Evaluation of different hemagglutinin-neuraminidase (HN) chimeras using a newly developed reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain [abstract]. 144th American Veterinary Medical Association Annual Convention Notes, July 14-28, 2007, Washington, DC. CD, paper #4439.

Protection against exotic Newcastle disease virus (NDV) challenge of chickens vaccinated with NDV vaccines made from different genetic lineages - (Abstract)

Miller, P.J., Estevez, C., Yu, Q., Suarez, D.L., King, D.J. 2007. Protection against exotic Newcastle disease virus (NDV) challenge of chickens vaccinated with NDV vaccines made from different genetic lineages [abstract]. International Poultry Forum Proceedings. p. 31.

Characterization of monoclonal antibodies produced against Avian metapneumovirus Sybtype C - (Abstract)

Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Characterization of monoclonal antibodies produced against Avian metapneumovirus Sybtype C. In: Proceedings of the 2006 Turkey Research Review and Avian Pneumovirus Symposium, September 27, 2006, Wilmar, Minnesota. 2006 CDROM.

SEQUENCE ANALYSIS OF THE COMPLETE GENOME OF AVIAN METAPNEUMOVIRUS SUBGROUP C COLORADO STRAIN: DEVELOPMENT OF A REVERSE GENETICS SYSTEM FOR THIS VIRUS - (Peer Reviewed Journal)

Yu, Q., Estevez, C. 2006. Sequence analysis of the complete genome of avian metapneumovirus Subgroup C Colorado strain: development of a reverse genetics system for this virus. In: Proceedings of the International Symposium on Avian Corona and Pneumoviruses and Complicating Pathogens, May 14-16, 2006, Rauischholzhausen, Germany. p. 6-15.

PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES PRODUCED AGAINST AVIAN METAPNEUMOVIRUS SUBTYPE C WHICH REACT TO THE NUCLEOCAPSID PROTEIN - (Peer Reviewed Journal)

Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Production and characterization of monoclonal antibodies produced against avian metapneumovirus subtype C which react to the nucleocapsid protein. Avian Diseases. 50(3):419-424.

VIRAL RESCUE FROM AN INFECTIOUS CLONE OF A MESOGENIC NEWCASTLE DISEASE VIRUS - (Abstract)

Estevez, C., Seal, B.S., Yu, Q. 2006. Viral rescue from an infectious clone of a mesogenic Newcastle disease virus. In: Proceedings of the 14th Annual Meeting of American Society for Virology, July 15, 2006, Madison, WI. p.217.

DEVELOPMENT OF A GREEN FLUORESCENT PROTEIN (GFP)-BASED MINIREPLICON SYSTEM FOR NEWCASTLE DISEASE VIRUS - (Abstract)

Estevez, C., Yu, Q. 2006. Development of a green fluorescent protein (gfp)-based minireplicon system for newcastle disease virus [abstract]. Ninth Southeastern Regional Virology Conference Program Book. p. 15.

PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES PRODUCED AGAINST AVIAN METAPNEUMOVIRUS SUBTYPE C WHICH REACT AGAINST THE NUCLEOCAPSID PROTEIN - (Abstract)

Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Production and characterization of monoclonal antibodies produced against Avian Metapneumovirus Subtype C which react against the nucleocapsid protein [abstract]. In: Proceedings of the 2006 Annual Meeting of American Association of Avian Pathologists, July 16-19, 2006, Honolulu, HI. p. 164.

A WILD GOOSE AVIAN METAPNEUMOVIRUS CONTAINING A LARGE ATTACHMENT GLYCOPROTEIN IS AVIRULENT BUT IMMUNOPROTECTIVE TO DOMESTIC TURKEYS - (Peer Reviewed Journal)

Bennett, R.S., Larue, R., Shaw, D., Yu, Q., Halvorson, D.A., Njenga, M. 2005. A wild goose avian metapneumovirus containing a large attachment glycoprotein is avirulent but immunoprotective to domestic turkeys. Journal of Virology.79(23):14834-14842.

SEQUENCE ANALYSIS OF THE COMPLETE GENOME OF AVIAN METAPNEUMOVIRUS SUBGROUP C COLORADO STRAIN: DEVELOPMENT OF A REVERSE GENETICS SYSTEM FOR THIS VIRUS - (Proceedings/Symposium)

Yu, Q. 2005. Sequence analysis of the complete genome of avian metapneumovirus subgroup C Colorado strain: development of a reverse genetics system for this virus. In: Proceedings of 2005 Turkey Research Review and Avian Pneumovirus Symposium, October 5, 2005, Willmar, MN. 2005 CDROM.

GENOMIC SEQUENCES OF LOW VIRULENCE AVIAN PARAMYXOVIRUS 1 (NEWCASTLE DISEASE VIRUS) ISOLATES OBTAINED FROM LIVE-BIRD MARKETS IN NORTH AMERICA NOT RELATED TO COMMONLY UTILIZED COMMERCIAL VACCINE STRAINS - (Peer Reviewed Journal)

Seal, B.S., Wise, M., Pedersen, J.C., Senne, D.A., Alvarez, R., Scott, M.A., King, D.J., Yu, Q., Kapczynski, D.R. 2005. Genomic sequences of low virulence avian paramyxovirus 1 (Newcastle disease virus) isolates obtained from live-bird markets in North America not related to commonly utilized commercial vaccine strains. Veterinary Microbiology. 106(1-2):7-16.

COMPARISON OF THE FULL LENGTH GENOME SEQUENCE OF AVIAN METAPNEUMOVIRUS SUBTYPE C WITH OTHER PARAMYXOVIRUSES INCLUDING HIGHLY VIRULENT NEWCASTLE DISEASE VIRUSES - (Peer Reviewed Journal)

Lwamba, H.M., Alvarez, R., Wise, M., Yu, Q., Halvorson, D., Njenga, M., Seal, B.S.2005. Comparison of the Full Length Genome Sequence of Avian Metapneumovirus Subtype C With Other Paramyxoviruses Including Highly Virulent Newcastle Disease Viruses. Virus Research. 107(1):83-92.

CHARACTERIZATION OF RECOMBINANT RESPIRATORY SYNCYTIAL VIRUSES WITH THE ATTACHMENT (G) PROTEIN DELETED OF THE REGION RESPONSIBLE FOR TYPE 2 T CELL RESPONSES AND PULMONARY EOSINOPHILIA - (Peer Reviewed Journal)

Elliott, M.B., Pryharski, K.S., Yu, Q., Boutilier, L.A., Campeol, N., Melville, K., Laughlin, T.S., Gupta, C.K., Lerch, R.A., Randolph, V.B., Lapierre, N.A., Heers Dack, K.M., Hancock, G.E. 2004. Characterization of recombinant respiratory syncytial viruses with the attachment (G) protein deleted of the region responsible for type 2 T cell responses and pulmonary eosinophilia. Journal of Virology. 78:8446-8454.

RECOMBINANT RESPIRATORY SYNCYTIAL VIRUSES LACKING THE C-TERMINAL THIRD OF THE ATTACHMENT (G) PROTEIN ARE IMMUNOGENIC AND ATTENUATED IN VIVO AND IN VITRO - (Peer Reviewed Journal)

Elliott, M.B., Pryharski, K.S., Yu, Q., Parks, C.L., Laughlin, T.S., Gupta, K., Lerch, R.A., Randolph, V.B., Lapierre, N.A., Heers Dack, K.M., Hancock, G.E. 2004. Recombinant Respiratory Syncytial Viruses Lacking the C-Terminal Third of the Attachment (G) Protein Are Immunogenic and Attenuated In Vivo and In Vitro. Journal of Virology. 2004 Jun:78(11):5773-83.