Projects

IMMUNOLOGIC AND PHARMACOLOGICAL INTERVENTIONS OF VECTOR-BORNE BABESIOSIS Appropriated (D)   Accession Number: 411502

HOST IMMUNOGENETICS PREDICT CLINICAL DISEASES IN OVINE PROGRESSIVE PNEUMONIA VIRUS INFECTED SHEEP Appropriated (D)   Accession Number: 411943

DETERMINANTS OF ANAPLASMA MARGINALE TRANSMISSION AT THE VECTOR/PATHOGEN INTERFACE Appropriated (D)   Accession Number: 411501

Publications

Persistently Infected Horses Are Reservoirs for Intrastadial Tick-Borne Transmission of the Apicomplexan Parasite Babesia equi - (Peer Reviewed Journal)

Ueti, M.W., Palmer, G.H., Scoles, G.A., Kappmeyer, L.S., Knowles Jr, D.P. 2008. Persistently Infected Horses Are Reservoirs for Intrastadial Tick-Borne Transmission of the Apicomplexan Parasite Babesia equi. Infection and Immunity. 76(8):3525-3529.

Transmission of Babesia caballi by Dermacentor nitens (Acari: Ixodidae) Is Restricted to One Generation in the Absense of Alimentary Reinfection on a Susceptible Equine Host - (Peer Reviewed Journal)

Schwint, N.O., Knowles Jr, D.P., Ueti, M.W., Kappmeyer, L.S., Scoles, G.A. 2008. Transmission of Babesia caballi by Dermacentor nitens (Acari: Ixodidae) Is Restricted to One Generation in the Absense of Alimentary Reinfection on a Susceptible Equine Host. Journal of Medical Entomology. 45(6):1152-1155.

Genomic analysis of Ovis aries (Ovar)MHC Class IIa loci - (Peer Reviewed Journal)

Hoesing, L.M., White, S.N., Kappmeyer, L.S., Herndon, D.R., Knowles Jr, D.P. 2008. Genomic analysis of Ovis aries (Ovar)MHC Class IIa loci. Immunogenetics. 60(3):167-176.

Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa - (Peer Reviewed Journal)

Brayton, K., Lau, A.O., Herndon, D.R., Hannick, L., Kappmeyer, L.S., Berens, S.J., Bidwell, S.L., Brown, W.C., Crabtree, J., Fadrosh, D., Feldblum, T., Forberger, H.A., Haas, B.J., Howell, J.M., Khouri, H., Koo, H., Mann, D.J., Norimine, J., Paulsen, I.T., Radune, D., Ren, Q., Smith, R.K., Suarez, C.E., White, O., Wortman, J.R., Knowles Jr, D.P., Mcelwain, T.F., Nene, V.M. 2007. Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa. PLoS Pathogens. 3(10):1401-1413.

DEVELOPMENT OF SPECIFIC IMMUNOGLOBULIN GA (IGGA) AND IGGB ANTIBODIES CORRELATES WITH CONTROL OF PARASITEMIA IN BABESIA EQUI INFECTION - (Peer Reviewed Journal)

Cunha, C.W., Mcguire, T.C., Kappmeyer, L.S., Hines, S.A., Lopez, A., Dellagostin, O.A., Knowles Jr, D.P. 2006. Development of Specific Immunoglobulin Ga (IgGa) and IgGb Antibodies Correlates with Control of Parasitemia in Babesia equi Infection. Clinical and Vaccine Immunology. 13(2):297-300.

ABILITY OF THE VECTOR TICK BOOPHILUS MICROPLUS TO ACQUIRE AND TRANSMIT BABESIA EQUI FOLLOWING FEEDING ON CHRONICALLY INFECTED HORSES WITH LOW LEVEL PARASITEMIA - (Peer Reviewed Journal)

Ueti, M.W., Palmer, G.H., Kappmeyer, L.S., Statdfield, M., Scoles, G.A., Knowles Jr, D.P. 2005. Ability of the Vector Tick Boophilus microplus To Acquire and Transmit Babesia equi following Feeding on Chronically Infected Horses with Low-Level Parasitemia. Journal of Clinical Microbiology. 43(8):3755-3759.

COMPLETE GENOME SEQUENCING OF ANAPLASMA MARGINALE REVEALS THAT THE SURFACE IS SKEWED TO TWO SUPERFAMILIES OF OUTER MEMBRANE PROTEINS - (Peer Reviewed Journal)

Brayton, K.A., Kappmeyer, L.S., Herndon, D.R., Dark, M.J., Tibbals, D.L., Palmer, G.H., Mcguire, T.C., Knowles Jr, D.P. 2005. Complete genome sequencing of anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proceedings of the National Academy of Sciences. 102(3):844-849.

EXPRESSION OF EQUI MEROZOITE ANTIGEN 2 DURING DEVELOPMENT OF BABESIA EQUI IN THE MIDGUT AND SALIVARY GLAND OF THE VECTOR TICK BOOPHILUS MICROPLUS - (Peer Reviewed Journal)

Ueti, M.W., G.H. Palmer, L.S. Kappmeyer, G.A. Scoles and D.P. Knowles. 2003. Expression of Equi Merozoite Antigen 2 during Development of Babesia equi in the Midgut and Salivary Gland of the vector tick Boophilus microplus. J. Clin. Micro. 41(12):5803-5809.

CONFORMATIONAL DEPENDENCE AND CONSERVATION OF AN IMMUNODOMINANT EPITOPE WITHIN THE BABESIA EQUI ERYTHROCYTE-STAGE SURFACE PROTEIN EQUI MEROSOITE ANTIGEN 1 - (Peer Reviewed Journal)

Clinical & Diagnostic Lab. Immunol.9(6)2002 1301-1306