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Understanding Cancer Series: Molecular Diagnostics
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Posted:
01/28/2005
Reviewed:
09/01/2006
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Molecular Diagnostics
Slide Number and Title
Normal Cell Communication
Cancer: A Communication Failure
Detecting the Troublemakers
Molecular Diagnostics
Gene Expression Patterns
Pause For a Science Lesson
Lesson 1: Genomic DNA and Genes
Lesson 2: Genes Express mRNA
Lesson 3: Expression Changes With Cell Type
Finding Genes With Microarrays
Finding Genes With Microarrays (cont.)
Using DNA Microarrays to Measure Gene Expression
Using DNA to Compare Cancer Cells to Normal Cells
Making Sense of the Data
Microarrays Come In Many Models
Cancer-Specific Gene Expression
Potential Markers for Metastasis
Subtyping Cancer
Lymphomas and Microarray Research
Microarray Predicts Survival
Finding New Drugs With Microarrays
HER-2/NEU Protein as Target
An Antibody Called Herceptin
Using Expression Patterns to Choose Treatments
SNPs Microarrays Check Drug Metabolism
Molecular Diagnostics and Proteomics
Proteomics Maps Protein Patterns
Proteomics Maps Protein Patterns (cont.)
Laser Capture Microdissection
Finding Subsets
Protein Patterns and Diagnosis
Importance of Diagnostic Test Sensitivity
Importance of Diagnostic Test Sensitivity (cont.)
Importance of Diagnostic Test Specificity
Importance of Diagnostic Test Specificity (cont.)
From Patterns to Screening Tool
From Known Samples to Serum Proteins
Molecular Mop
Serum Proteins Can Serve as Markers
Molecular Diagnostics Has Many Uses
In the Future
Clinical Trials: Making the Future the Present
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