Volume 9, Number 2, February 2003

Molecular Typing of IberoAmerican Cryptococcus neoformans Isolates

Wieland Meyer,* Alexandra Castañeda,† Stuart Jackson,*‡ Matthew Huynh,* Elizabeth Castañeda,† and the IberoAmerican Cryptococcal Study Group
*University of Sydney, Sydney, Australia; †Instituto Nacional de Salud, Bogotá, Colombia; and ‡University of Western Sydney, Campbelltown, Australia

Figure 2. Dendrogram of the polymerase chain reaction-fingerprinting patterns obtained with the primer M13 from a selection of the IberoAmerican isolates studied. All the isolates fall into eight major molecular types, which fall into three major groups corresponding to Cryptococcus neoformans var. grubii, serotype A, with two molecular types VNI and VNII; C. neoformans var. neoformans, serotype D, with the molecular type VNIV; and C. neoformans var. gattii serotypes B and C, with the molecular types VGI, VGII, VGIII and VGIV. In addition to the three major clusters we can see the intermediate molecular type VNIII, representing the AD hybrids.

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This page last reviewed March 20, 2003

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention