Projects

ENVIRONMENTAL AND GENETIC FACTORS AFFECTING PATHOGEN PERSISTENCE IN ANIMAL WASTE AND TRANSFER TO CROPS Appropriated (D)   Accession Number: 409718

DETECTION OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY AGENTS IN LIVESTOCK, WILDLIFE, AGRICULTURAL PRODUCTS, AND THE ENVIRONMENT Appropriated (D)   Accession Number: 413072

DEVELOPMENT OF DETECTION TECHNOLOGIES FOR TOXINS AND THEIR VALIDATION IN FOOD MATRICES Appropriated (D)   Accession Number: 410156

DEVELOPMENT OF DETECTION TECHNOLOGIES FOR BACTERIAL NEUROTOXINS AND THEIR VALIDATION IN FOOD MATRICES Specific Cooperative Agreement (S)   Accession Number: 410477

Publications

Validation of a Cell-Free Translation Assay for Detecting Shiga Toxin 2 in bacterial culture - (Peer Reviewed Journal) - (31-Mar-09)

Immunochemical technologies for replacement of rodent bioassays in sensitive detection of toxins in foods - (Abstract) - (01-Oct-08)

Prion infected Meat-and-Bone Meal is still infectious after biodiesel production - (Peer Reviewed Journal)

Bruederle, C.E., Hnasko, R.M., Kraemer, T., Garcia, R.A., Haas, M.J., Marmer, W.N., Carter, J.M. 2008. Prion infected Meat-and-Bone Meal is still infectious after biodiesel production. PLoS Pathogens. Available: http://dx.plos.org/10.1371/journal.pone.0002969

Effect of food matrices on the biological activity of ricin - (Peer Reviewed Journal)

He, X., Lu, S.S., Cheng, L.W., Rasooly, R., Carter, J.M. 2008. Effect of food matrices on the biological activity of ricin. Journal of Food Protection 71(10):2053-2058.

Detection of botulinum neurotoxin-A activity in food by peptide cleavage assay - (Peer Reviewed Journal)

Rasooly, R., Stanker, L.H., Carter, J.M., Do, P.M., Cheng, L.W., He, X., Brandon, D.L. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. International Journal of Food Microbiiology. 126 (2008):135-139

Effects of purification on the bioavailability of botulinum neurotoxin type A - (Peer Reviewed Journal)

Cheng, L.W., Onisko, B.C., Johnson, E.A., Reader, J.R., Griffey, S.M., Larson, A.E., Tepp, W.H., Stanker, L.H., Brandon, D.L., Carter, J.M. 2008. Effects of purification on the bioavailability of botulinum neurotoxin type A. Toxicology. 249(2008):123-129.

Sensitive, Preclinical Detection of Prions in Brain by nanospray liquid chromatography/tandem mass spectrometry - (Peer Reviewed Journal)

Onisko, B.C., Silva, C.J., Dynin, I.A., Erickson, M.L., Vensel, W.H., Hnasko, R.M., Requena, J.R., Carter, J.M. 2007. Sensitive, Preclinical Detection of Prions in Brain by nanospray liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry. 21(24):4023-4026.

Sonication Induced Intermediate in Prion Protein Conversion - (Peer Reviewed Journal)

Zukas, A.A., Bruederle, C.E., Carter, J.M. 2008. Sonication Induced Intermediate in Prion Protein Conversion. Protein and Peptide Letters. 53(2):206-211

Application of a real time PCR method to detect castor toxin contamination in fluid milk and eggs - (Peer Reviewed Journal)

He, X., Carter, J.M., Brandon, D.L., Cheng, L.W., Mckeon, T.A. 2007. Application of a real time PCR method to detect castor toxin contamination in fluid milk and eggs. Journal of Agricultural and Food Chemistry. 55:6897-6902

Mass Spectrometric Detection of Attomole Amounts of the Prion Protein by nanoLC-MS-MS - (Peer Reviewed Journal)

Onisko, B.C., Dynin, I.A., Requena, J.R., Silva, C.J., Erickson, M.L., Carter, J.M. 2007. Mass Spectrometric Detection of Attomole Amounts of the Prion Protein by nanoLC-MS-MS. Journal of American Society for Mass Spectrometry. Volume(18); 1070-1079

Molecular Approaches for the Identification of Toxin in Foods - (Abstract) - (23-Feb-07)

Detection of castor contamination by real-time polymerase chain reaction - (Peer Reviewed Journal)

He, X., Brandon, D.L., Chen, G.Q., McKeon, T.A., Carter, J.M. 2007. Detection of castor contamination by real-time polymerase chain reaction. Journal of Agricultural and Food Chemistry. 55(2):545-550.

A COFACTOR LIMITS THE PMCA CONVERSION REACTION - (Abstract)

Zukas, A.A., Carter, J.M. 2006. A cofactor limits the pmca conversion reaction [Abstract]. Strategies, advances and trends towards protection of society. p 290.

PV-1 LABELS TRANS-CELLULAR OPENINGS IN MOUSE ENDOTHELIAL CELLS AND IS NEGATIVELY REGULATED BY VEGF - (Peer Reviewed Journal)

Hnasko, R.M., Carter, J.M., Medina, F., Lisanti, M. 2006. Pv-1 labels trans-cellular openings in mouse endothelial cells and is negatively regulated by vegf. Cell Cycle. 5(17):2021-28.

SONICATION INDUCED INTERMEDIATE IN PRION CONVERSION - (Abstract)

Zukas, A.A., Carter, J.M. 2006. Sonication induced intermediate in prion conversion. [Abstract]. ACS National Meeting. Poster BIOL55

BIOAVAILABILITY OF CRUDE RICIN IN FOOD MATRICES - (Abstract)

Cheng, L.W., Brandon, D.L., He, X., Chen, G.Q., Carter, J.M. 2006. Bioavailability of crude ricin in food matrices. [Abstract]. ACS National Meeting and Exposition. Poster AGFD 64

DEVELOPMENT OF NEW MONOCLONAL ANTIBODIES SPECIFIC FOR BOTULINUM NEUROTOXIN TYPE A - (Abstract)

Stanker, L.H., Merrill, P.A., Cheng, L.W., Carter, J.M., Brandon, D.L. 2006. Development of new monoclonal antibodies specific for botulinum neurotoxin type a. [Abstract]. ACS National Meeting. Oral Presentation AGRO 235.

DEVELOPMENT OF MONOCLONAL ANTIBODIES SPECIFIC FOR RICIN - (Abstract)

Brandon, D.L., Cheng, L.W., He, X., Carter, J.M. 2006. Development of monoclonal antibodies specific for ricin. [Abstract]. ACS National Meeting and Exposition. Oral Presentation AGRO 234

MASS SPECTROMETRIC DETECTION OF ATTOMOLE AMOUNTS OF THE PRION PROTEIN, PRP 27-30, BY NANOLC-MS-MS - (Abstract)

Onisko, B.C., Requena, J., Silva, C.J., Dynin, I.A., Carter, J.M. 2006. Mass spectrometric detection of attomole amounts of the prion protein, prp 27-30, by nanolc-ms-ms. [Abstract]. 232nd ACS National Meeting and Exposition. Poster AGFD 200

DETECTION OF CASTOR CONTAMINATION IN GROUND BEEF BY REAL-TIME PCR - (Abstract)

He, X., Brandon, D.L., Chen, G.Q., Mckeon, T.A., Carter, J.M. 2006. Detection of castor contamination in ground beef by real-time pcr. [Abstract]. ACS National Meeting and Exposition. Poster AGFD 18.

STRAIN-SPECIFIC PRP-RES IN VITRO AMPLIFICATION BY THE PMCA TECHNIQUE - (Abstract)

Zukas, A.A., Carter, J.M. 2006. Strain-specific prp-res in vitro amplification by the pmca technique. [Abstract]. Cambridge Healthtec Institute, Transmissible Spongiform Encephalopathies. Poster #12.

NEW RESEARCH AT THE USDA ARS ON DETECTION OF CRUDE BOTULINUM NEUROTOXIN IN FOOD - (Abstract)

Carter, J.M., Binder, R.G., Stanker, L.H., Brandon, D.L. 2005. New research at the usda ars on detection of crude botulinum neurotoxin in food. [Abstract]. Interagency Botulism Research Committee. Poster 4.

PRION RESEARCH AT THE WESTERN REGIONAL RESEARCH CENTER - (Abstract)

Carter, J.M., Onisko, B., Silva, C., Stanker, L. Requena, J.R., 2005. Prion research at the Western Regional Research Center [abstract]. International Symposium on the New Prion Biology: Basic Science, Diagnosis and Therapy, April 7-9, 2005, Venice, Italy. Poster P17.

TECHNIQUES AND CHALLENGES IN THE DIAGNOSIS OF PRION DISEASES. - (Abstract)

Stanker, L.H., Carter, J.M. 2004. Techniques and challenges in the diagnosis of prion diseases.. Meeting Abstract.