Encourage use of DSSTox Standard
Chemical Structure Fields and standardized SDF structure data format files for publishing chemical toxicity data files;
Apply strict DSSTox Chemical Information Quality Review Procedures to the annotation of chemical structures and chemical information associated with toxicity data;
Coordinate with outside
public efforts to encourage chemical structure annotation, data
standardization, and open public access to toxicity data files;
Involve
the user community in the effort to migrate more public toxicity
data and toxicity related chemical lists into the DSSTox standardized format for publishing;
Provide full, open access to toxicity data files for chemical structure-analog
searching, and for facilitating development of improved models for
predicting toxicity based on chemical structure;
Coordinate project development with the goals and objectives of
EPA's Computational Toxicology
Program to enhance the ability of EPA scientists and regulators
to integrate, explore, and utilize chemical toxicity data from a
structural perspective.
Distributed:
Decentralized set of standardized, field-delimited
data files, each separately authored and maintained, that
are able to accommodate diverse chemical toxicity data
content;
Structure-Searchable:
Standardized format (SDF) structure data
files that can be readily imported into available Structure Browsers or Chemical
Relational Databases and structure-searched;
Tox: Toxicity data as it exists
in widely disparate forms in current public databases,
spanning diverse toxicity endpoints, test systems, levels
of biological content, degrees of summarization, and information
content.
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