The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Purpose of This PDQ Summary

Added text to state that some of the reference citations in the summary are accompanied by a level-of-evidence designation.

Localized Osteosarcoma/Malignant Fibrous Histiocytoma of Bone

Added text to state that pathologic fracture at diagnosis was associated with a worse overall outcome (cited Bramer et al. as reference 25).

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