Untreated Childhood Medulloblastoma
Recurrent Childhood Medulloblastoma

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Untreated childhood medulloblastoma is a tumor for which no treatment has been given. The child may have received drugs or treatment to relieve symptoms caused by the tumor.

Standard treatment of average risk childhood medulloblastoma is usually surgery and radiation therapy to the brain and spinal cord, with or without chemotherapy.

One of the treatments being studied in clinical trials for average risk medulloblastoma in children 3 years and older is surgery followed by radiation therapy (including conformal radiation therapy), with chemotherapy during and after radiation therapy.

Standard treatment of high risk childhood medulloblastoma may include surgery followed by radiation therapy to the brain and spinal cord, with or without chemotherapy. Treatment within a clinical trial may be considered for children with high risk medulloblastoma.

Treatment of childhood medulloblastoma in children younger than 3 years of age is usually within a clinical trial and may include the following:

• Surgery followed by chemotherapy to delay radiation therapy.
• Surgery followed by high-dose chemotherapy with stem cell transplant.
• Chemotherapy only.
• Chemotherapy followed by conformal radiation therapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with untreated childhood medulloblastoma.

Standard treatment of recurrent childhood medulloblastoma may include surgery with or without chemotherapy and/or stereotactic radiation therapy.

Some of the treatments being studied in clinical trials for recurrent childhood medulloblastoma include the following:

• A clinical trial of surgery followed by high-dose chemotherapy and stem cell transplant using the patient's own stem cells.
• A clinical trial of a new therapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent childhood medulloblastoma.

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