Readings in Genomics and Health

General readings (all links last accessed 2/2008)

The Human Genome Project is Complete. How Do We Develop a Handle For the Pump? (518KB)
Julian Little, et al. Am J Epidemiol (2003)

World Health Organization (2002): Report on Genomics and World Health 
With recommendations to ensure that genome technology is used to reduce rather than exacerbate global inequalities in health status.

Translation of Genomic Research Into Health Care.
Khoury MJ, Beskow L, Gwinn ML, JAMA (letter), 2001

Genetics and Public Health - Need for Information, Integration and Infrastructure
Timothy Baker
ASTHO Report, Sept-Oct 1998

From Genes to Public Health: Applications of Genetics in Disease Prevention
American Journal of Public Health (1996)

Genetics and Genomics in Practice: The Continuum from Genetic Disease to Genetic Information in Health and Disease
Muin J. Khoury M.D., Ph.D.
National Office of Public Health Genomics, Centers for Disease Control and Prevention

Genomic Profiling to Promote A Healthy Lifestyle: Not Ready for Prime Time
S.B. Haga, M.J. Khoury, and W. Burke
Nature Genet 2003;34:347-350

Genomics and Its Impact on Medicine and Society - A 2001 Primer 
A publication of the U.S. Department of Energy Human Genome Program

Helping High-Risk Families: Medical and Public Health Approaches
Commentary by Ann M. Malarcher, PhD, MSPH; Wayne H. Giles, MD, MS; Muin J. Khoury, MD,PhD
Genetics in Medicine (2002)

Human Genetics and Emerging Infectious Diseases: Issues and Prevention Opportunities
Janet M. McNicholl and James M. Hughes
U.S. Medicine, June 1998, p.4

The Integration of Genomics into Public Health Research, Policy, and Practice in the United States
L. Beskow, et al, Community Genetics (July 2001)

The Intersection of Genetics, Public Health, and Preventive Medicine
Steven S. Coughlin
Am J Prev Medicine, February, 1999

Relationship Between Medical Genetics and Public Health: Changing the Paradigm of Disease Prevention and the Definition of a Genetic Disease
Muin J. Khoury
American Journal of Medical Genetics, 1997;17:289-291

The Role of Genomics in Public Health and Disease Prevention
K. Steinberg, et al.
JAMA Vol. 286, p 1635, October 3, 2001

Testimony of Dr. Muin Khoury
Director, CDC National Office of Public Health Genomics to the House Committee on Energy and Commerce, subcommittee on Health, May 22, 2003

The New England Journal of Medicine Genomic Medicine Series (all links last accessed 2/2008)

Genomics as a Probe for Disease Biology
Burke W.
N Engl J Med 2003; 349:969-974, Sep 4, 2003.

Ethical, Legal, and Social Implications of Genomic Medicine
Clayton E. W.
N Engl J Med 2003; 349:562-569, Aug 7, 2003.

Cardiovascular Disease
Nabel E. G.
N Engl J Med 2003; 349:60-72, Jul 3, 2003.

Breast and Ovarian Cancer
Wooster R., Weber B. L.
N Engl J Med 2003; 348:2339-2347, Jun 5, 2003.

Molecular Diagnosis of the Hematologic Cancers
Staudt L. M.
N Engl J Med 2003; 348:1777-1785, May 1, 2003.

Alzheimer's Disease and Parkinson's Disease
Nussbaum R. L., Ellis C. E.
N Engl J Med 2003; 348:1356-1364, Apr 3, 2003.

Hereditary Colorectal Cancer
Lynch H. T., de la Chapelle A.
N Engl J Med 2003; 348:919-932, Mar 6, 2003.

Inheritance and Drug Response
Weinshilboum R.
N Engl J Med 2003; 348:529-537, Feb 6, 2003.

Population Screening in the Age of Genomic Medicine
Khoury M. J., McCabe L. L., McCabe E. R.B.
N Engl J Med 2003; 348:50-58, Jan 2, 2003.

Genomic Medicine — A Primer
Guttmacher A. E., Collins F. S.
N Engl J Med 2002; 347:1512-1520, Nov 7, 2002