New article published in the American Journal of Epidemiology on Turning the Pump Handle: Evolving Methods for Integrating the Evidence on Gene-Disease Association on September 5, 2007 (70KB)
	Recent article published by AAPA News focuses on personalized medicine and the role of family history, genetics, and genomic applications in patient care. See quotes by Dr. Muin Khoury of CDC’s National Office of Public Health Genomics and other experts. (576KB)
	September public health genomics seminar presented by CDC “How do we monitor the impact of genomics on population health?" Sep 20, 2007, Rockville, MD (ENVISION – Atlanta, GA)

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

HFE gene in primary and secondary hepatic iron overload
Sebastiani G & Walker AP
World J Gastroenterol 2007 Sep;13(35):4673-89

IL-7Ralpha and multiple sclerosis risk
Harley JB
Nat Genet 2007 Sep;39(9):1053-4

Genetic and genomic insights into the molecular basis of atherosclerosis
Chen Y, et al.
Cell Metab 2007 Sep;6(3):164-79

The novel human SHOX allelic variant database
Niesler B, et al.
Hum Mutat 2007 Aug

Searching for genes influencing a complex disease: the case of coeliac disease
Naluai AT, et al.
Eur J Hum Genet 2007 Aug

New gene associations in osteoarthritis: what do they provide, and where are we going?
Ikegawa S
Curr Opin Rheumatol 2007 Sep;19(5):429-34

Sporadic gastric cancer; a complex interaction of genetic and environmental risk  factors
McColl KE, et al.
Am J Gastroenterol 2007 Sep;102(9):1893-5

Adults' values and attitudes about genetic testing for obesity risk in children
Segal ME, et al.
Int J Pediatr Obes 2007;2(1):11-21

Genomic Tests for Ovarian Cancer Detection and Management
Myers ER, et al.
Evid Rep Technol Assess (Full Rep) 2006 Oct(145):1-100

A structured simple form for ordering genetic tests is needed to ensure coupling  of clinical detail (phenotype) with DNA variants (genotype) to ensure utility in  publication and databases
Cotton RG, et al.
Hum Mutat 2007 Aug

 

Assessing family history of heart disease in primary care consultations: a qualitative study
Hall R, et al.
Fam Pract 2007 Aug

Familial liability and schizophrenia phenotypes: A polydiagnostic approach
Peralta V & Cuesta MJ
Schizophr Res 2007 Aug

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending September 5, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies

For more information on HuGE, please visit the HuGENet™ home page