President Bush Announces Recipients of Presidential Medal of Freedom; Francis Collins Honored (20KB)
	Recently signed Food and Drug Administration Amendments Act of 2007, Public Law No. 110-85, contains a provision related to genetic testing safety and quality (section 1103).

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Cardiovascular Disease	Diabetes
University of Pittsburgh cardiologists identify new cardiac arrest gene,   EurekAlert, October 31	Research identifies two genes that may play a role in insulin resistance,  News-Medical.Net, October 29

Gene interactions in depression: pathways out of darkness
Harvey M, et al.
Trends Genet 2007 Oct

Genetic polymorphisms in susceptibility to Type 1 Diabetes
Alizadeh BZ & Koeleman BP
Clin Chim Acta 2007 Oct

Pharmacogenetics of glucose-lowering drug treatment: a systematic review
Bozkurt O, et al.
Mol Diagn Ther 2007;11(5):291-302

The genetic predisposition to adverse outcome after trauma
Giannoudis PV, et al.
J Bone Joint Surg Br 2007 Oct;89(10):1273-9

Running in the Family or Swimming in the Gene Pool: Discriminating between Family History and Genetic Risk in Illness Perceptions
Riggs AL & Giuliano TA
J Health Psychol 2007 Nov;12(6):883-94

New links to the pathogenesis of Crohn disease provided by genome-wide association scans
Mathew CG
Nat Rev Genet 2007 Oct

Mechanisms of Disease: genetics of rheumatoid arthritis-ethnic differences in disease-associated genes
Yamada R & Yamamoto K
Nat Clin Pract Rheumatol 2007 Nov;3(11):644-50

Genome-wide association studies in aging-related processes such as diabetes mellitus, atherosclerosis and cancer
Kronenberg F
Exp Gerontol 2007 Sep

Myocilin allele-specific glaucoma phenotype database
Hewitt AW, et al.
Hum Mutat 2007 Oct

Pathway-Based Approaches for Analysis of Genomewide Association Studies
Wang K, et al.
Am J Hum Genet 2007 Oct;81(6)

Development of genomic reference materials for Huntington disease genetic testing
Kalman L, et al.
Genet Med2007 Oct,; 9:10

Molecular screening for familial hypercholesterolaemia: consequences for life and disability insurance
Homsma SJ, et al.
Eur J Hum Genet 2007 Oct

Molecular Testing for Microsatellite Instability and DNA Mismatch Repair Defects  in Hereditary and Sporadic Colorectal Cancers - Ready for Prime Time?
Soreide K
Tumour Biol 2007 Oct;28(5):290-300

Modeling the impact of genetic screening technologies on healthcare: theoretical  model for asthma in children
Gutierrez de Mesa E, et al.
Mol Diagn Ther 2007;11(5):313-23

 

Relevance of family history of suicide in the long-term outcome of bipolar disorders
Romero S, et al.
J Clin Psychiatry 2007 Oct;68(10):1517-21

Incidence of Coronary Artery Disease in Siblings of Patients With Premature Coronary Artery Disease: 10 Years of Follow-up
Vaidya D, et al.
Am J Cardiol 2007 Nov;100(9):1410-5

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending October 31, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page