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 Thursday, July 26, 2007 Volume 19   Number 4
Weekly Update banner Family History Population Research Genomics in Practice General Public Family History Population Research Genomics in Practice General Public
  This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
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Muin J. Khoury 2007 Summer Public Health Institute
The University of Minnesota’s School of Public Health hosted its 6th Annual Summer Public Health Institute on May 21-June 8, 2007, which included new courses on public health genomics and a roundtable discussion with keynote speaker Muin Khoury, MD, PhD, director of CDC’s National Office of Public Health Genomics, and other experts in public health genomics.

Links for the Institute
 Main Page  •  Courses  •  Faculty  •  Lectures  •  Roundtable  non-gov warning icon
 > View Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
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Genomics Announcements
   
CDC sponsored material

New article Family history and prevalence of diabetes in the US population: 6-year results from the National Health and Nutrition Examination Survey (NHANES, 1999-2004) , written by Rodolfo Valdez, Paula Yoon, Tiebin Liu, and Muin Khoury, was published in advance of the printed version in Diabetes Care on July 18, 2007.

   
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New July issue of PHG Foundation's monthly newsletter, featuring genomics and policy news non-gov warning icon


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
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Cancer

Cardiovascular Disease
Breast cancer diagnosed later in African
Americans
non-gov warning icon (last accessed 2/2008) Reuters Health, July 23
Largest ever genetic study of coronary artery diseasenon-gov warning icon Medical News Today, July 21

Mechanism for gene silencing in skin cancer discoverednon-gov warning icon GEN, July 19

Common gene mutations affect heart disease,  non-gov warning icon (last accessed 2/2008) Reuters Health, July 20

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Chronic Disease

Spontaneous genetic mutations responsible for half of autism cases, Yahoo News, July 24

Mathematical model identifies genes which battle Hepatitis Cnon-gov warning icon EurekAlert, July 19

Gene therapy for Parkinson's hitches ride on
virus
non-gov warning icon Science Daily, July 22

 

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ELSI (Ethical, Legal and Social Issues)

Genetic Testing
DNA discrimination at worknon-gov warning icon news.com.au, July 24 Embryo Screeningnon-gov warning icon New York Times, July 24

Parents blame doctor for genetic disordernon-gov warning icon My Fox Tampa Bay, July 23

 

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Other News

Genetic counselor looks at cancer's hereditary ties to a patientnon-gov warning icon Indystar, July 25

Scientists scour genome for clues about
disease
non-gov warning icon NPR, July 20

Interleukin genetics initiates program to develop genetic test to guide more effective weight control in obese patientsnon-gov warning icon Medical News Today, July 25

First genome-wide study of infectious disease opens new avenues for HIV treatment,
vaccines
,  non-gov warning icon NIH News, July 19

Study: Defibrillators help in genetic cases, Star Tribune, July 24

Lubert Stryer wins National Medal of Sciencenon-gov warning icon News-Medical.Net, July 19

New method for early disease diagnosisnon-gov warning icon Science Daily, July 22

Protein protects anti-cancer gene from chemical shutdownnon-gov warning icon EurekAlert, July 19

Family, more than genes, helps drive divorce,  non-gov warning icon (last accessed 2/2008) Medline Plus, July 20

 
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Genomics in Scientific Literature
Featured Item

Genetic Variation associated with Ischemic Heart Failure: A HuGE Review and Meta-Analysis
Kitsios G & Zintzaras E
Am J Epidemiol 2007 Jul

 General Articles

Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of LAMBDA, BRCAPRO, Myriad II, and modified Couch models
Lindor NM, et al.
Fam Cancer 2007 Jul

Familial carotid body tumours: is there a role for genetic screening?
Jani P, et al.
J Laryngol Otol 2007 Jul:1-5

 

 Family History

Family History of Premature Coronary Heart Disease and Coronary Artery Calcification. Multi-Ethnic Study of Atherosclerosis (MESA)
Nasir K, et al.
Circulation 2007 Jul

Family history and prevalence of diabetes in the US population: 6-year results from the National Health and Nutrition Examination Survey (NHANES, 1999 2004)
Valdez R, et al.
Diabetes Care 2007 Jul

Family History Predicts Stress Fracture in Active Female Adolescents
Loud KJ, et al.
Pediatrics 2007 Jul

Risk estimation for familial breast cancer: improving the system of counselling
Gregory H, et al.
Eur J Hum Genet 2007 Jul

Inter-informant agreement and prevalence estimates for substance use disorders: Direct interview versus family history method
Vandeleur CL, et al.
Drug Alcohol Depend 2007 Jul

 

 Genetic Testing

Common pathways in inflammatory diseases revealed by genomics
Massey DC & Parkes M
Gut 2007 Jul

Rheumatic Fever and rheumatic heart disease: genetics and pathogenesis
Guilherme L, et al.
Scand J Immunol 2007 Aug;66(2-3):199-207

Review article: the genetic basis of haemochromatosis
Griffiths WJ
Aliment Pharmacol Ther 2007 Aug;26(3):331-42

Effects of genetic polymorphism of cytochrome P450 enzymes on the pharmacokinetics of benzodiazepines
Fukasawa T, et al.
J Clin Pharm Ther 2007 Aug;32(4):333-41

Incorporation of genetic model parameters for cost-effective designs of genetic association studies using DNA pooling
Ji F, et al.
BMC Genomics 2007 Jul;8(1):238

Vitamin C deficiency and scurvy are not only a dietary problem but are codetermined by the haptoglobin polymorphism
Delanghe JR, et al.
Clin Chem 2007 Aug;53(8):1397-400

GPDTI: A Genetic Programming Decision Tree Induction method to find epistatic effects in common complex diseases
Estrada-Gil JK, et al.
Bioinformatics 2007 Jul;23(13):i167-i174

Innate immunogenetics: a tool for exploring new frontiers of host defence
Bochud PY, et al.
Lancet Infect Dis 2007 Aug;7(8):531-42

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending July 25, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases

Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Congenital Anomalies
Symptoms, Signs, and Ill-defined Conditions
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page

 

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The CDC National Office of Public Health Genomics makes available the above information as a public service only. Providing
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This reference links to a non-governmental website
 Provides link to non-governmental sites and does not necessarily represent the views of the Centers  for Disease Control and Prevention.
Page last reviewed: July 26, 2007 (archived document)
Content Source: National Office of Public Health Genomics