An article on the SchizophreniaGene  database (SzGene), Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database, was recently published in Nature Genetics. The SzGene database displays key characteristics, including genotype distributions, from individual genetic association studies as well as the results of continually updated meta-analyses. Genetic associations with statistically significant meta-analyses in the SzGene database were graded in this article using the interim guidelines for assessing the cumulative evidence on genetic associations developed by HuGENet™.

One new HuGE Review has been registered with HuGENet™ since the last issue of the ‘What's New’:

• Influence of the ADRB2 gene polymorphisms on the response to 2-agonists in airway diseases: a HuGENet systematic review and meta-analysis by Matteo Bonini, et al., from the Department University of Genoa, Italy.
  
  
• List of completed HuGE Reviews
• List of HuGE Review topics under development

As of July 9, 2008, the HuGE Navigator  contains 35,344 research studies, referencing 3,719 genes,and 1,935 health outcomes/diseases. Both epidemiologic studies and review articles can be found in the database which includes 71 HuGE Reviews and 773 meta-analyses.

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