The BOH consists of 11 members appointed by and responsible to the Maricopa County Board of Supervisors for staggered four year terms. Five are appointed by district, one is a supervisor, one is a physician and four are at-large. The Arizona Revised Statues provide for this in Title 36.

The BOH elects a president, vice-president of finance and a Physician Representative. The role of the Director of the health department is to participate and work with the Board but is not considered a member. The director serves as the secretary of the board as a non-voting member. The president is also a member of the finance committee. The executive committee consists of President of Board of Health, Vice-President-Finance, two At-Large members of which one is a physician. The President also may, with the approval of the Board, appoint special committees.