Projects

UNDERSTANDING SOIL-PLANT-HUMAN/ANIMAL FOOD SYSTEMS AND NUTRIENT BIOAVAILABILITY TO IMPROVE HUMAN HEALTH Appropriated (D)   Accession Number: 408012

BIOAVAILABILITY OF FE AND ZINC IN BIOFORTIFIED CROPS Grant (G)   Accession Number: 408158

BIOFORTIFIED CROPS FOR IMPROVED HUMAN NUTRITION Reimbursable (R)   Accession Number: 409487

Publications

Effects of Ascorbic Acid, Phytic Acid and Tannic Acid on Iron Bioavailability from Reconstituted Ferritin Measured by an In Vitro Digestion/Caco-2 Cell Model - (Peer Reviewed Journal) - (08-Jul-08)

Effects of Ascorbic Acid, Phytic Acid and Tannic Acid on Ferritin-Iron Bioavailability as Determined Using an In Vitro Digestion/Caco-2 Cell Model - (Peer Reviewed Journal) - (10-Jun-08)

Iron bioavailability to piglets from red and white common beans (Phaseolus vulgaris L.) - (Peer Reviewed Journal)

Tan, S., Yeung, C., Glahn, R.P., Welch, R.M., Lei, X., Miller, D.D. 2008. Iron bioavailability to piglets from red and white common beans (Phaseolus vulgaris L.). Journal of Agriculture and Food Chemistry.

Genotypic variation in wheat grain fructan content revealed by a simplified HPLC method - (Peer Reviewed Journal) - (25-Oct-07)

Cecum is the major degradation site of ingested inulin in young pigs - (Peer Reviewed Journal)

Yasuda, K., Maiorano, R., Welch, R.M., Miller, D., Lei, X. 2007. Cecum is the major degradation stie of ingested inulin. Journal of Nutrition. 137:399-2404.

Screening of iron bioavailability patterns in eight bean (Phaseolus vulgaris L.) genotypes using the Caco-2 cell in vitro model - (Peer Reviewed Journal)

Ariza-Nieto, M., Blair, M., Welch, R.M., Glahn, R.P. 2007. Screening of iron bioavailability patterns in eight bean (Phaseolus vulgaris L.) genotypes using the Caco-2 cell in vitro model. Journal of Agricultural and Food Chemistry. 55:7950-7956.

Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine - (Peer Reviewed Journal)

Tako, E., Glahn, R.P., Welch, R.M., Lei, X., Yasuda, K., Miller, D. 2008. Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine. British Journal of Nutrition. Volume 99:472-480.

Iron bioavailability from maize and beans: a comparison of human measurements with Caco-2 cell and algorithm predictions - (Peer Reviewed Journal)

Beisiegel, J.M., Hunt, J.R., Glahn, R.P., Welch, R.M., Menkir, A., Maziya-Dixon, B.B. 2007. Iron bioavailability from maize and beans: a comparison of human measurements with Caco-2 cell and algorithm predictions. American Journal of Clinical Nutrition. 86:388-396.

The effects of Selenocysteine Se-Methyltransferase on Selenium metabolism in Broccoli - (Abstract)

Zhou, X., Lyi, M., Heller, L., Rutzke, M., Welch, R.M., Kochian, L.V., Li, L. 2007. The effects of Selenocysteine Se-Methyltransferase on Selenium metabolism in Broccoli [abstract]. Plant Physiology. p. 113.

Kaempferol in red and pinto bean seed (PHASEOLUS VULGARIS L.) coats inhibits iron bioavailability using an in vitro digestion/human CACO-2 cell model - (Peer Reviewed Journal)

Hu, Y., Cheng, Z., Heller, L., Krasnoff, S.B., Glahn, R.P., Welch, R.M. 2006. Kaempferol in red and pinto bean seed (PHASEOLUS VULGARIS L.) coats inhibits iron bioavailability using an in vitro digestion/human CACO-2 cell model. Journal of Agricultural and Food Chemistry. 54:9254-9261.

Moving toward a more physiological model: application of mucin to refine the in vitro digestion/Caco-2 cell culture system - (Peer Reviewed Journal)

Jin, F., Welch, R.M., Glahn, R.P. 2006. Moving toward a more physiological model: application of mucin to refine the in vitro digestion/Caco-2 cell culture system. Journal of Agricultural and Food Chemistry. 54:8962-8967.

SUPPLEMENTAL DIETARY INULIN AFFECTS BIOAVAILABILITY OF IRON PRESENT IN CORN AND SOYBEAN MEAL TO YOUNG PIGS - (Peer Reviewed Journal)

Yasuda, K., Roneker, K.R., Miller, D.D., Welch, R.M., Lei, X. 2006. Supplemental dietary inulin affects bioavailability of iron present in corn and soybean meal to young pigs. Journal of Nutrition. 136:3033-3038.

Iron bioavailability from maize and beans: a comparison of human and Caco-2 cell measurements - (Abstract)

Beisiegel, J.M., Hunt, J.R., Glahn, R.P., Welch, R.M., Menkir, A., Maziya-Dixon, B.B. 2007. Iron bioavailability from maize and beans: a comparison of human and Caco-2 cell measurements [abstract]. Program Abstracts, Consequences and Control of Micronutrient Deficiencies: Science, Policy, and Programs - Defining the Issues. April 16-18, 2007. Istanbul, Turkey. p. 103.

FECAL PHYTATE EXCRETION VARIES WITH DIETARY PHYTATE AND AGE IN WOMEN - (Peer Reviewed Journal)

Joung, H., Jeun, B., Li, S., Kim, J., Woodhouse, L.R., King, J., Welch, R.M., Paik, H. 2007. Fecal phytate excretion varies with dietary phytate and age in women. Journal of the American College of Nutrition. 26(3):295-302.

IRON (FE) BIOAVAILABILITY AND THE DISTRIBUTION OF ANTI-FE NUTRITION BIOCHEMICALS IN THE UNPOLISHED, POLISHED GRAIN AND BRAN FRACTION OF FIVE RICE GENOTYPES - (Peer Reviewed Journal)

Prom-U-Thai, C., Glahn, R.P., Welch, R.M., Huang, L., Rerkasem, B. 2006. Iron (fe) bioavailability and the distribution of anti-fe nutrition biochemicals in the unpolished, polished grain and bran fraction of five rice genotypes. Journal of the Science of Food and Agriculture. 86(8):1209-1215.

NUTRITIOUS SUBSISTENCE FOOD SYSTEMS - (Review Article)

Graham, R.D., Welch, R.M., Saunders, D.A., Ortiz-Monasterio, I., Bouis, H.E., Bonierbale, M., De Hann, S., Burgos, G., Burgos, G., Thiele, G., Lira, R., Meisner, C.A., Beebe, S.E., Potts, M.J., Kadian, M., Hobbs, P.R., Gupta, R.K., Twomlow, S. 2007. Nutritious subsistence food systems. Advances in Agronomy. 92:1-74.

THE EFFECTS OF SELENOCYSTEINE SE-METHYLTRANSFERASE ON SELENIUM METABOLISM IN TRANSGENIC BROCCOLI - (Abstract)

Zhou, X., Lyi, S., Heller, L., Rutzke, M., Welch, R.M., Kochian, L.V., Li, L. 2006. The effects of selenocysteine se-methyltransferase on selenium metabolism in transgenic broccoli [abstract]. American Society of Plant Biologists Annual Meeting. p. 226.

SHIFTING THE PH PROFILE OF ASPERGILLUS NIGER PHYA PHYTASE TO MATCH THE STOMACH PH ENHANCES ITS EFFECTIVENESS AS AN ANIMAL FEED ADDITIVE - (Peer Reviewed Journal)

Kim, T., Mullaney, E.J., Porres, J.M., Roneker, K.R., Crowe, S., Rice, S., Ko, T., Ullah, A.H., Daly, C.B., Welch, R.M., Lei, X.G. 2006. Shifting the ph profile of Aspergillus niger PhyA phytase to match the stomach ph enhances its effectiveness as an animal feed additive. Applied and Environmental Microbiology. 72(6):4397-4403.

HISTORICAL SHIFTS IN THE SEED MINERAL MICRONUTRIENT CONCENTRATION OF U.S. HARD RED WINTER WHEAT GERMPLASM - (Peer Reviewed Journal)

Garvin, D.F., Welch, R.M., Finley, J.W. 2006. Historical shifts in the seed mineral micronutrient concentration of U.S. hard red winter wheat germplasm. Journal of the Science of Food and Agriculture. 86:2213-2220.

A CACO-2 CELL MODEL PREDICTS RELATIVE IRON ABSORPTION FROM TROPICAL MAIZE BY WOMEN - (Abstract)

Beisiegel, J.M., Glahn, R.P., Welch, R.M., Menkir, A., Maziya-Dixon, B.B., Hunt, J.R. 2006. A caco-2 cell model predicts relative iron absorption from tropical maize by women [abstract]. FASEB J. 20(4):A624.

ZINC EFFECTS ON CADMIUM ACCUMULATION AND PARTITIONING IN NEAR-ISOGENIC LINES OF DURUM WHEAT THAT DIFFER IN GRAIN CADMIUM CONCENTRATION - (Peer Reviewed Journal)

Hart, J.J., Welch, R.M., Norvell, W.A., Kochian, L.V. 2005. Zinc effects on cadmium accumulation and partitioning in near-isogenic lines of durum wheat that differ in grain cadmium concentration. New Phytologist. 167:391-401.

MEAT AND ASCORBIC ACID CAN PROMOTE FE AVAILABILITY FROM FE-PHYTATE BUT NOT FROM FE-TANNIC ACID COMPLEXES - (Peer Reviewed Journal)

Engle-Stone, R., Yeung, A., Welch, R.M., Glahn, R.P. 2005. Meat and ascorbic acid can promote fe availability from fe-phytate but not from fe-tannic acid complexes. Journal of Agricultural and Food Chemistry. 53:10276-10284.

SELENOCYSTEINE SE-METHYLTRANSFERASE AND SE-METHYLSELENOCYSTEINE SYNTHESIS IN BROCCOLI - (Abstract)

Li, L., Lyi, S.M., Heller, L.I., Rutzke, M., Welch, R.M., Kochian, L.V. 2005. Selenocysteine se-methyltransferase and se-methylselenocysteine synthesis in broccoli. American Society of Plant Biologists Annual Meeting. P. 554.

FROM QUANTITY TO QUALITY - THE IMPORTANCE OF FERTILIZERS IN HUMAN NUTRITION - (Review Article)

Dibbs, D., Roberts, T., Welch, R.M. 2005. From quantity to quality - the importance of fertilizers in human nutrition. Proceedings of the International Symposium on Information Technology in Soil Fertility and Fertilizer Management, Satellite Symposium, 15th International Plant Nutrition Colloquium, September 14-15, 2005, Beijing,China. p. 20-25.

KRIGING ON HIGHLY SKEWED DATA FOR DTPA-EXTRACTABLE SOIL ZN WITH AUXILIARY INFORMATION FOR PH AND ORGANIC CARBON - (Peer Reviewed Journal)

Wu, J., Norvell, W.A., Welch, R.M. 2006. Kriging on highly skewed data for dtpa-extractable soil zn with auxiliary information for ph and organic carbon. Geoderma. 134:187-199.

PREBIOTICS AND IRON BIOAVAILABILITY - IS THERE A CONNECTION?¿ - (Literature)

Yeung, C., Miller, D., Welch, R.M., Glahn, R.P. 2005. Prebiotics and iron bioavailability - is there a connection?¿. Journal of Food Science. 70:1288-1292.

"BIOFORTIFICATION" - A SUSTAINABLE AGRICULTURAL APPROACH TO ADDRESSING MICRONUTRIENT MALNUTRITION - (Popular Publication)

Welch, R.M. 2005. "Biofortification" - a Sustainable Agricultural Approach to Addressing Micronutrient Malnutrition. Feedinfo News Service Scientific Reviews. May 2005. Available from URL: http://www.feedinfo.com.

ZINC EFFECTS ON CADMIUM ACCUMULATION AND PARTITIONING IN NEAR-ISOGENIC LINES OF DURUM WHEAT THAT DIFFER IN GRAIN CADMIUM CONCENTRATION - (Peer Reviewed Journal)

Hart, J.J., Welch, R.M., Norvell, W.A., Clarke, J.M., Kochian, L.V. 2005. Zinc effects on cadmium accumulation and partitioning in near-isogenic lines of durum wheat that differ in grain cadmium concentration. New Phytologist. 167:391-401.

MOLECULAR AND BIOCHEMICAL CHARACTERIZATION OF THE SELENOCYSTEINE SE-METHYLTRANSFERASE GENE AND SE-METHYLSELENOCYSTEINE SYNTHESIS IN BROCCOLI (BRASSICA OLERACEA VAR. ITALICA) - (Peer Reviewed Journal)

Li, L., Lyi, S.M., Heller, L., Rutzke, M., Welch, R.M., Kochian, L.V. 2005. Molecular and biochemical characterization of the selenocysteine se-methyltransferase gene and se-methylselenocysteine synthesis in broccoli (brassica oleracea var. italica). Plant Physiology. 138:409-420.

POTENTIAL FOR IMPROVING BIOAVAILABLE ZINC IN WHEAT GRAIN (TRITICUM SP.) THROUGH PLANT BREEDING - (Peer Reviewed Journal)

Welch, R.M., House, W.A., Monasterio, I., Cheng, Z. 2005. Potential for improving bioavailable zinc in wheat grain (triticum sp.) through plant breeding. Journal of Agricultural and Food Chemistry. 53:2176-2180.

GENOTYPE-ENVIRONMENT INTERACTIONS AND STABILITY ANALYSES OF KERNEL-IRON AND -ZINC CONCENTRATIONS IN TROPICAL MAIZE - (Peer Reviewed Journal) - (04-Nov-04)

AGRICULTURE: THE REAL NEXUS FOR ENHANCING BIOAVAILABLE MICRONUTRIENTS IN FOOD CROPS - (Review Article)

Welch, R.M. 2005. Agriculture: the real nexus for enhancing bioavailable micronutrients in food crops. Journal of Trace Elements in Medicine and Biology. 18:299-307.

AGRICULTURE: THE REAL NEXUS FOR ENHANCING BIOAVAILABLE MICRONUTRIENTS IN FOOD CROPS - (Review Article)

Welch, R.M., Graham, R.D. 2005. Agriculture: the real nexus for enhancing bioavailable micronutrients in food crops. Journal of Trace Elements in Medicine and Biology. 18:299-307.

FARMING FOR HEALTH: THE FUTURE OF AGRICULTURE - (Proceedings/Symposium)

Welch, R.M. 2004. Farming for health: the future of agriculture. In: Crozier,C., editor. Southern Plant Nutrient Management Conference Proceedings. October 5-6, 2004, Olive Branch, MS. p.35-41.

QTLS FOR PHYTATE IN RICE GRAIN AND THEIR RELATIONSHIP WITH IRON - (Proceedings/Symposium)

Huynh, L., Stangoulis, J., Welch, R.M., Graham, R. 2004. Qtls for phytate in rice grain and their relationship with iron. International Crop Science Congress Proceedings. p. 13-27.

AN IMPROVED UNDERSTANDING OF SOIL CD RISK TO HUMANS AND LOW COST METHODS TO REMEDIATE SOIL CD RISKS - (Peer Reviewed Journal)

Chaney, R.L., Reeves, P.G., Ryan, J.A., Simmons, R.W., Welch, R.M., Angle, J.S. 2004. An improved understanding of soil cd risk to humans and low cost methods to remediate soil cd risks. Biometals. 17(5):549-553.

COMPARTMENTATION OF CADMIUM IN HIGH- AND LOW- CD ACCUMULATING, NEAR ISOGENIC LINES OF DURUM WHEAT - (Abstract)

Hart, J.J., Welch, R.M., Norvell, W.A., Kochian, L.V. 2004. Compartmentation of cadmium in high- and low- cd accumulating, near isogenic lines of durum wheat. American Society of Plant Biologists Annual Meeting. p. 256.

GENOTYPIC VARIATION IN COMMON BEAN IN RESPONSE TO ZINC DEFICIENCY IN CALCAREOUS SOIL - (Peer Reviewed Journal)

Hacisalihoglu, G., Ozturk, L., Cakmak, I., Welch, R.M., Kochian, L.V. 2004. Genotypic variation in common bean in response to zinc deficiency in calcareous soil. Plant And Soil Journal. 259:71-83.

ASSESSMENT OF IRON BIOAVAILABILITY FROM 20 ELITE LATE-MATURING TROPICAL MAIZE VARIETIES USING AN IN VITRO DIGESTION/CACO-2 CELL MODEL - (Peer Reviewed Journal)

Oikeh, S.O., Menkir, A., Maziya-Dixon, B., Welch, R.M., Glahn, R.P. 2004. Assessment of iron bioavailability from 20 elite late-maturing tropical maize varieties using an in vitro digestion/caco-2 cell model. Journal of the Science of Food and Agriculture. 84:1202-1206.

BREEDING FOR MICRONUTRIENTS IN STAPLE FOOD CROPS FROM A HUMAN NUTRITION PERSPECTIVE - (Review Article)

WELCH, R.M., GRAHAM, R.D. BREEDING FOR MICRONUTRIENTS IN STAPLE FOOD CROPS FROM A HUMAN NUTRITION PERSPECTIVE. JOURNAL OF EXPERIMENTAL BOTANY. 2004. V. 55(396). P. 353-364.

AN IMPROVED UNDERSTANDING OF SOIL CD RISK TO HUMANS - (Abstract)

Chaney, R.L., Reeves, P.G., Ryan, J.A., Simmons, R.W., Welch, R.M. 2003. An improved understanding of soil Cd risk to humans [abstract]. Proceedings of the International Symposium on Health Impacts of Cadmium Exposure in China. p. 49-51.

IRON "BIOFORTIFICATION" OF TROPICAL MAIZE TO REDUCE HUMAN IRON DEFFICIENCY IN WEST AFRICA - (Peer Reviewed Journal)

OIKEH, S.O., MENKIR, A., MAZIYA-DIXON, B., WELCH, R.M., GLAHN, R.P. 2003. IRON "BIOFORTIFICATION" OF TROPICAL MAIZE TO REDUCE HUMAN IRON DEFFICIENCY IN WEST AFRICA. JOURNAL OF PLANT NUTRITION. 26:2307-2319.

ASSESSMENT OF CONCENTRATIONS OF TRACE MINERALS AND BIOAVAILABLE IRON IN GRAINS OF EARLY-MATURING TROPICAL MAIZE VARIETIES - (Peer Reviewed Journal)

OIKEH, S.O., MENKIR, A., MAZIYA-DIXON, B., WELCH, R.M., GLAHN, R.P. ASSESSMENT OF CONCENTRATIONS OF TRACE MINERALS AND BIOAVAILABLE IRON IN GRAINS OF EARLY-MATURING TROPICAL MAIZE VARIETIES. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2003. v. 51. p. 3688-3694.

BREEDING FOR MICRONUTRIENT DENSITY IN STAPLE FOOD CROPS - (Abstract)

Welch, R.M. 2003. Breeding for micronutrient density in staple food crops [abstract]. Society for Experimental Biology Proceedings/Comparative Biology & Physiology: Part A. 134:5116.

FARMING OF NUTRITIOUS FOODS: AGRICULTURAL TECHNOLOGIES FOR IMPROVED HUMAN HEALTH - (Proceedings/Symposium)

WELCH, R.M. FARMING OF NUTRITIOUS FOODS: AGRICULTURAL TECHNOLOGIES FOR IMPROVED HUMAN HEALTH. INTERNATIONAL FERTILIZER INDUSTRY ASSOCIATION-FOOD AND AGRIUCLTURE ORGANIZATION OF THE UNITED NATIONS AGRICULTURE CONFERENCE. 2003.

SEED MICRONUTRIENT CONTENTS OF A HISTORICAL COLLECTION OF HARD RED WINTER WHEATS - (Abstract) - (10-Nov-02)