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U.S. Department of Health and Human Services

Fact Sheet

CDC's Role in Preventing Extensively Drug-Resistant Tuberculosis (XDR TB)

Posted: April 2007

For more information on TB, please see the TB Fact Sheets page

PDF version formatted for print (136 kb)

The Centers for Disease Control and Prevention (CDC) is collaborating with other federal agencies and international partners to raise awareness and enhance strategies for TB prevention worldwide by

  • Strengthening TB services for people living with HIV/AIDS

The President’s Emergency Plan for AIDS Relief (PEPFAR), through funding and technical support, helps host countries strengthen laboratory infrastructure, provide staff training, and screen patients who are HIV-infected for TB. Host countries are working to improve patient management, drug-resistance surveillance, and monitoring and evaluation efforts.

  • Assembling outbreak response teams

Teams of subject matter experts from CDC are prepared to be rapidly deployed to help host country governments and the World Health Organization (WHO) when outbreaks occur or other needs are identified.

  • Improving access to TB drugs

As a member of the Green Light Committee and through support of the Global Drug Facility, CDC is helping to increase access to quality-assured, lower-cost second-line drugs to treat drug-resistant TB.

  • Developing international TB testing standards

These recommendations are being designed to ensure more accurate and rapid detection and treatment of drug-resistant TB. They will include standards for second-line drug susceptibility testing, new anti-TB drug regimens, and better diagnostic testing.

  • Building capacity of health care providers

By providing technical support and training, CDC helps to build the capacity of frontline health care providers to diagnose and ensure completion of treatment, which aids in preventing drug resistance.

  • Reconvening the Federal TB Task Force

This task force was originally created to respond to the emergence of multidrug-resistant tuberculosis (MDR TB) in the U.S. in the 1990s. Today, the Federal TB Task Force is developing an action plan to combat XDR TB.

  • Providing technical assistance to expand program capacity

CDC and partners are working directly with host countries to implement improved infection control measures, rapid case detection, effective treatment, and drug resistance surveillance.

  • Supporting TB communication and education efforts

Information on XDR TB is being disseminated regularly and widely. This information is regularly updated on the CDC and partner websites, as well as being presented at national and international conferences and events.

Note: In addition to CDC, U.S. government partners include the President’s Emergency Plan for AIDS Relief (PEPFAR), United States Agency for International Development (USAID) Tuberculosis Control Assistance Program (TBCAP), and the National Institutes of Health (NIH). Other domestic partners include the National Tuberculosis Controllers Association (NTCA) and local and state TB programs. International partners include the World Health Organization (WHO), the Stop TB Partnership, the International Union Against Tuberculosis and Lung Disease (IUATLD), national TB programs, and ministries of health.

Additional Information

CDC. Extensively Drug-resistant Tuberculosis (XDR TB)

CDC. Extensively Drug-Resistant Tuberculosis - United States, 1993—2006

World Health Organization. Extensively drug-resistant tuberculosis (XDR TB) website


Last Reviewed: 05/18/2008
Content Source: Division of Tuberculosis Elimination
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention


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