[Federal Register: March 27, 2006 (Volume 71, Number 58)]
[Notices]
[Page 15187-15188]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr27mr06-76]
[[Page 15187]]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[60Day-06-06AX]
Proposed Data Collections Submitted for Public Comment and
Recommendations
In compliance with the requirement of Section 3506(c)(2)(A) of the
Paperwork Reduction Act of 1995 for opportunity for public comment on
proposed data collection projects, the Centers for Disease Control and
Prevention (CDC) will publish periodic summaries of proposed projects.
To request more information on the proposed projects or to obtain a
copy of the data collection plans and instruments, call 404-639-5960
and send comments to Seleda Perryman, CDC Assistant Reports Clearance
Officer, 1600 Clifton Road, MS-D74, Atlanta, GA 30333 or send an e-mail
to omb@cdc.gov.
Comments are invited on: (a) Whether the proposed collection of
information is necessary for the proper performance of the functions of
the agency, including whether the information shall have practical
utility; (b) the accuracy of the agency's estimate of the burden of the
proposed collection of information; (c) ways to enhance the quality,
utility, and clarity of the information to be collected; and (d) ways
to minimize the burden of the collection of information on respondents,
including through the use of automated collection techniques or other
forms of information technology. Written comments should be received
within 60 days of this notice.
Proposed Project
Risk Perception, Worry, and Use of Ovarian Cancer Screening among
Women at High, Elevated, and Average Risk of Ovarian Cancer--New--
National Center for Chronic Disease Prevention and Health Promotion
(NCCDPHP), Centers for Disease Control and Prevention (CDC).
Background and Brief Description
Accounting for an estimated 22,220 cases and 16,210 deaths in 2005,
ovarian cancer is the most frequent cause of death from gynecologic
malignancy in the United States. In over 80 percent of patients,
ovarian cancer presents at a late clinical stage, affording a five-year
survival rate of only 35 percent. For cases where ovarian cancer is
identified in Stage I, however, the five-year survival rate exceeds 90
percent.
Identifying a woman's risk of ovarian cancer plays a large role in
determining the appropriateness of having her undergo screening. It is
only for women with a strong family history of ovarian and/or breast
cancer or women with a hereditary genetic risk for ovarian cancer that
the currently available screening modalities of CA 125 and transvaginal
ultrasound are recommended.
Statements from the scientific and medical community regarding
recommendations for ovarian cancer screening play only a partial role
in a woman's decision to undergo screening exams. Numerous
psychological and sociological factors can affect this decision as
well, including a woman's knowledge, attitudes, beliefs, and
experiences. For instance, a woman's experience of cancer within her
family or experience with a friend who has had cancer may influence a
woman's screening decisions.
The literature also notes that women with a family history of
ovarian cancer report increased worry and high levels of perceived
risk. A positive association has also been shown between screening
behavior and family history. Recent studies indicate, however, that
screening is not occurring in proportion to women's levels of risk.
These findings underscore the need for a better understanding of how
perceived risk of ovarian cancer may influence worry about cancer and
ultimately screening behavior.
To address these issues, the Division of Cancer Prevention and
Control (DCPC), at the National Center for Chronic Disease Prevention
and Health Promotion, Centers for Disease Control and Prevention, is
conducting a study to examine the effects of family history of cancer,
knowledge about ovarian cancer, worry and/or anxiety, and perceived
risk of cancer on the likelihood of a woman undergoing screening for
ovarian cancer. By also examining other psycho-social factors such as a
woman's closeness to a relative or friend with cancer, coping style,
cancer worry, use of other cancer screening tests, social support, and
provider's recommendations, the study will elucidate the causal pathway
leading from actual risk (as measured by family history) through
perceived risk to intent to undergo screening and actual screening
behavior.
The proposed study will consist of two tasks:
Task 1, a brief eligibility screener (5 minutes) preceding a
baseline survey administered through a computer-assisted telephone
interview (CATI) program. Approximately 2000 women will be asked a
series of questions over a 35-minute time period. Questions will cover
key variables related to ovarian cancer screening including coping,
anxiety, perceived risk, worry, personal cancer history, family cancer
history, closeness with family or friends who have had cancer,
screening behavior, and knowledge of ovarian cancer.
Task 2, a follow-up questionnaire will be administered, also using
a CATI program, to approximately 1800 of the women included in the
baseline questionnaire. Each of the women will be contacted one year
after they complete the baseline survey. The researchers anticipate a
10 percent attrition of the sample between baseline and follow-up. In
the follow-up, women will be asked a series of questions over a 15-
minute time period. The purpose of this data collection effort is to
determine if risk perception has changed and to ask about screening for
ovarian cancer, since the baseline questionnaire was administered. All
data will be collected over a three-year time period. There are no
costs to respondents except their time to participate in the survey.
Estimated Annualized Burden Table
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No. of Average burden
Respondents No. of Responses per per response Total burden
Respondents respondent (in hrs.) (in hours)
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Telephone Screener.......................... 10667 1 5/60 889
Baseline Survey (women 30 or older)......... 667 1 35/60 389
Follow-up Survey (completed Baseline Survey) 600 1 15/60 150
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Total................................... ............... ............... ............... 1428
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[[Page 15188]]
Dated: March 20, 2006.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. 06-2934 Filed 3-24-06; 8:45 am]
BILLING CODE 4163-18-P