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Draft Toxicological Review of Thallium: In Support of the Summary Information in the Integrated Risk Information System (IRIS)

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[Federal Register: February 15, 2008 (Volume 73, Number 32)]
[Notices]
[Page 8867-8868]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr15fe08-50]

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ENVIRONMENTAL PROTECTION AGENCY
[FRL-8530-2; Docket ID No. EPA-HQ-ORD-2008-0057]

Draft Toxicological Review of Thallium: In Support of the Summary
Information in the Integrated Risk Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of Public Comment Period.

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SUMMARY: EPA is announcing a public comment period for the external
review draft document titled, ``Toxicological Review of Thallium: In
Support of Summary Information on the Integrated Risk Information
System (IRIS)'' (NCEA-S-2949). The EPA intends to consider comments and
recommendations from the public and the expert panel meeting, which
will be scheduled at a later date and announced in the Federal
Register, when EPA finalizes the draft document. The public comment
period will provide opportunities for all interested parties to comment
on the document. EPA intends to forward public comments submitted in
accordance with this notice to the external peer-review panel prior to
the meeting for their consideration.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination public review under applicable information quality
guidelines. This document has not been formally disseminated by EPA. It
does not represent and should not be construed to represent any Agency
policy or determination.
    The draft document and EPA's peer-review charge are available via
the Internet on NCEA's home page under the Recent Additions and the
Data and Publications menus at http://www.epa.gov/ncea. When finalizing
the draft document, EPA intends to consider any public comments that
EPA receives in accordance with this notice.

DATES: The public comment period begins February 15, 2008, and ends
April 15, 2008. Technical comments should be in writing and must be
received by EPA by April 15, 2008. EPA intends to submit comments from
the public received by this date for consideration by the external peer
review panel.

ADDRESSES: The draft ``Toxicological Review of Thallium: In Support of
Summary Information on the Integrated Risk Information System (IRIS)''
is available via the Internet on the National Center for Environmental
Assessment's (NCEA) home page under the Recent Additions and the Data
and Publications menus at http://www.epa.gov/ncea. A limited number of
paper copies are available from NCEA's Technical Information Staff,
telephone: 703-347-8561; facsimile: 703-347-8691. If you are requesting
a paper copy, please provide your name, mailing address, and the
document title. The 1988 Midwest Research Institute (MRI) study
referenced in the draft Toxicological Review of Thallium is available
by calling EPA's IRIS Hotline at 202-566-1676, by facsimile at 202-566-
1749, or by e-mail at hotline.iris@epa.gov.
    Comments may be submitted electronically via http://www.regulations.gov,
by mail, by facsimile, or by hand delivery/courier.

[[Page 8868]]

Please follow the detailed instructions as provided in the
SUPPLEMENTARY INFORMATION section of this notice.

FOR FURTHER INFORMATION CONTACT: For information on the public comment
period, contact the Office of Environmental Information Docket;
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail: 
ORD.Docket@epa.gov.
    If you have questions about the document, contact Susan Rieth, IRIS
Staff, National Center for Environmental Assessment, (8601P), U.S. EPA,
1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone: 703-
347-8582; facsimile: 703-347-8689; or e-mail: rieth.susan@epa.gov.

SUPPLEMENTARY INFORMATION:

I. Summary of Information About the Integrated Risk Information System
(IRIS)

    IRIS is a database that contains potential adverse human health
effects information that may result from chronic (or lifetime) exposure
to specific chemical substances found in the environment. The database
(available on the Internet at http://www.epa.gov/iris) contains
qualitative and quantitative health effects information for more than
540 chemical substances that may be used to support the first two steps
(hazard identification and dose-response evaluation) of a risk
assessment process. When supported by available data, the database
provides oral reference doses (RfDs) and inhalation reference
concentrations (RfCs) for chronic health effects, and oral slope
factors and inhalation unit risks for carcinogenic effects. Combined
with specific exposure information, government and private entities can
use IRIS data to help characterize public health risks of chemical
substances in a site-specific situation and thereby support risk
management decisions designed to protect public health.

II. How To Submit Technical Comments to the Docket at 
http://www.regulations.gov

    Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2008-
0057 by one of the following methods:
    • http://www.regulations.gov: Follow the on-line instructions for
submitting comments.
    • E-mail: ORD.Docket@epa.gov.
    • Fax: 202-566-1753.
    • Mail: Office of Environmental Information (OEI) Docket
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
    • Hand Delivery: The OEI Docket is located in the EPA
Headquarters Docket Center, EPA West Building, Room 3334, 1301
Constitution Ave., NW., Washington, DC. The EPA Docket Center Public
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through
Friday, excluding legal holidays. The telephone number for the Public
Reading Room is 202-566-1744. Such deliveries are only accepted during
the docket's normal hours of operation, and special arrangements should
be made for deliveries of boxed information.
    If you provide comments by e-mail or hand delivery, please submit
one unbound original with pages numbered consecutively, and three
copies of the comments. For attachments, provide an index, number pages
consecutively with the comments, and submit an unbound original and
three copies.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2008-0057. Please ensure that your comments are submitted within the
specified comment period. Comments received after the closing date will
be marked ``late,'' and may only be considered if time permits. It is
EPA's policy to include all comments it receives in the public docket
without change and to make the comments available online at 
http://www.regulations.gov, including any personal information provided,
unless a comment includes information claimed to be Confidential
Business Information (CBI) or other information whose disclosure is
restricted by statute. Do not submit information that you consider to
be CBI or otherwise protected through http://www.regulations.gov
or e-mail. The http://www.regulations.gov Web site is an ``anonymous
access'' system, which means EPA will not know your identity or contact
information unless you provide it in the body of your comment. If you
send an e-mail comment directly to EPA without going through 
http://www.regulations.gov, your e-mail address will be automatically
captured and included as part of the comment that is placed in the public
docket and made available on the Internet. If you submit an electronic
comment, EPA recommends that you include your name and other contact
information in the body of your comment and with any disk or CD-ROM you
submit. If EPA cannot read your comment due to technical difficulties
and cannot contact you for clarification, EPA may not be able to
consider your comment. Electronic files should avoid the use of special
characters, any form of encryption, and be free of any defects or
viruses. For additional information about EPA's public docket visit the
EPA Docket Center homepage at http://www.epa.gov/epahome/dockets.htm
    Docket: All documents in the docket are listed in the
http://www.regulations.gov index. Although listed in the index, some
information is not publicly available, e.g., CBI or other information
whose disclosure is restricted by statute. Certain other material, such
as copyrighted material, will be publicly available only in hard copy.
Publicly available docket materials are available either electronically
in http://www.regulations.gov or in hard copy at the OEI Docket in the
EPA Headquarters Docket Center.

    Dated: February 11, 2008.
Rebecca Clark,
Deputy Director, National Center for Environmental Assessment.
[FR Doc. E8-2882 Filed 2-14-08; 8:45 am]
BILLING CODE 6560-50-P

 
 


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