Carriedo C, Rubio R, Moreno S, Pintado V, Buzon L, Barros C; International Conference on AIDS.

Int Conf AIDS. 1993 Jun 6-11; 9: 399 (abstract no. PO-B12-1586).

Cooperative Study Group, Madrid, Spain.

OBJECTIVES: To determine the predictive factors for survival in Kaposi's Sarcoma (KS). METHODS AND PATIENTS: We reviewed the hospital records of 200 patients with KS associated with AIDS, diagnosed in 8 hospitals of Madrid from 1984 to April-1992. Survival curves were plotted according to the Kaplan-Meier method. Difference in survival was compared using log-rank test. RESULTS: The overall median survival was 15 months (range: 0-55), with a three years survival probability of 17%. The factors associated with a negative impact on survival were: B symptoms (p < 0.001); III-IV stages (UCLA) (p < 0.001); pulmonary or gastrointestinal involvement (p < 0.05); hemoglobin < 10 g/dl (p < 0.001); leukocytes < 5500/mm3 (p < 0.01); CD4 lymphocytes < 400/mm3; CD8 lymphocytes < 800/mm3 (p < 0.01) and LDH > 500 UI/L (p < 0.01). CONCLUSIONS: The survival of patients with Kaposi's Sarcoma associated with AIDS, is short. The factors related to poor survival are: advanced stages, B symptoms, visceral involvement, anemia, leukopenia, CD4 depletion and increase of LDH.

Publication Types:

• Meeting Abstracts

Keywords:

• Acquired Immunodeficiency Syndrome
• CD4-Positive T-Lymphocytes
• Forecasting
• Humans
• Models, Theoretical
• Prognosis
• Proportional Hazards Models
• Research
• Risk Factors
• Sarcoma, Kaposi
• Survival
• Survival Analysis
• Survival Rate
• methods
• mortality
• statistics & numerical data

Other ID:

• 93335148

UI: 102204525

From Meeting Abstracts