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*THE NATIONAL CHILDREN'S STUDY OF ENVIRONMENTAL EFFECTS ON CHILD HEALTH AND DEVELOPMENT |
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The National Children's Study is a population-based cohort study that will examine the effects of environmental influences on the health and development of more than 100,000 childr...
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A COMMUNITY-BASED CHILDREN'S PESTICIDE EXPOSURE MEASUREMENT STUDY IN JACKSONVILLE, FLORIDA |
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Children's exposures to pesticides and chemicals in consumer products may be different, and in some cases, higher than exposures for adults. The U.S. Environmental Protection Ag...
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A COMMUNITY-BASED CHILDREN'S PESTICIDE EXPOSURE MEASUREMENT STUDY IN JACKSONVILLE, FLORIDA: RESULTS FROM THE AGGREGATE EXPOSURE ASSESSMENT |
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Young children may be more susceptible to pesticides because they are undergoing rapid development and more likely to engage in activities in which they directly contact contaminat...
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A FEASIBILITY STUDY EXAMINING THE POTENTIAL FOR HUMAN EXPOSURE TO PET-BORNE DIAZINON RESIDUES FOLLOWING RESIDENTIAL TURF APPLICATIONS |
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The domestic dog may be a vehicle for translocation of pesticide residues following residential applications to turf. In addition, human occupants may be exposed to residues depo...
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A FEASIBILITY STUDY EXAMINING THE POTENTIAL FOR HUMAN HEALTH EXPOSURE TO PET-BORNE DIAZINON RESIDUES FOLLOWING RESIDENTIAL TURF APPLICATIONS |
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The domestic dog may be a vehicle for translocation of pesticide residues following residential applications to turf. In addition, human occupants may be exposed to residues depo...
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A FRAMEWORK FOR ASSESSING HEALTH RISK OF ENVIRONMENTAL EXPOSURES TO CHILDREN (FINAL) |
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EPA has released a final report entitled, A Framework for Assessing Health Risk of Environmental Exposures to Children, which examines the impact of potential exposures duri...
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A PILOT STUDY OF CHILDREN'S TOTAL EXPOSURE TO PERSISTENT PESTICIDES AND OTHER PERSISTENT ORGANIC POLLUTANTS (CTEPP) |
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The Pilot Study of Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants (CTEPP) investigated the aggregate exposures of 257 preschool children...
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A PILOT STUDY TO EVALUATE METHODS FOR THE ASSESSMENT OF EXPOSURE OF SMALL CHILDREN TO PESTICIDES IN THE RESIDENTIAL ENVIRONMENT |
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A pilot study was conducted to evaluate methods of assessment of exposure of infants and toddlers to pesticide residues around the household. ine homes with children aged six month...
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A PILOT STUDY USING AN ACCELEROMETER TO EVALUATE A CAREGIVER'S INTERPRETATION OF AN INFANT OR TODDLER'S ACTIVITY LEVEL AS RECORDED IN A TIME ACTIVITY DIARY |
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Linking a young child's activity pattern data with samples that are collected during an exposure assessment is important in evaluating uptake dose rates associated with environment...
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A PROBABILISTIC ARSENIC EXPOSURE ASSESSMENT FOR CHILDREN WHO CONTACT CHROMATED COPPER ARSENATE ( CAA )-TREATED PLAYSETS AND DECKS: PART 2 SENSITIVITY AND UNCERTAINTY ANALYSIS |
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A probabilistic model (SHEDS-Wood) was developed to examine children's exposure and dose to chromated copper arsenate (CCA)-treated wood, as described in Part 1 of this two part pa...
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A- THE NATIONAL CHILDREN'S STUDY |
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The National Children's Study (NCS) will be the largest long-term study of children's health and development ever conducted in the United States. The NCS will examine a broad rang...
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ACCOUNTING FOR THE ENDOGENEITY OF HEALTH AND ENVIRONMENTAL TOBACCO SMOKE EXPOSURE IN CHILDREN: AN APPLICATION TO CONTINUOUS LUNG FUNCTION |
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The goal of this study is to estimate an unbiased exposure effect of environmental tobacco smoke (ETS) exposure on children's continuous lung function. A majority of the evidence ...
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ACUTE EFFECTS OF AIR POLLUTION ON RESPIRATORY SYMPTOMS AND PEAK FLOW MEASUREMENTS OF SYMPTOMATIC AND ASYMPTOMATIC CHILDREN IN NIZHNI TAGIL, RUSSIA |
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A panel study with 85 elementary school children of 9 to 11 years old was carried out during March 16 - May 16, 1998 in Nizhni Tagil, Russia. All of the children were recruited f...
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ADULT AND CHILDREN'S EXPOSURE TO 2,4-D FROM MULTIPLE SOURCES AND PATHWAYS |
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In this study, we investigated the 2,4-dichlorophenoxyacetic acid (2,4-D)
herbicide exposures of 135 preschool-aged children and their adult caregivers at 135 homes in North Carol...
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AGGREGATE EXPOSURES OF NINE PRESCHOOL CHILDREN TO PERSISTENT ORGANIC POLLUTANTS AT DAY CARE AND AT HOME |
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In the summer of 1997, we measured the aggregate exposures of nine preschool children, ages two to five years, to a suite of organic pesticides and other persistent organic pollu...
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AGRICULTURAL HEALTH STUDY/PESTICIDE EXPOSURE STUDY: YEAR 1 MEASUREMENT RESULTS |
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The Agricultural Health Study (AHS) is a prospective epidemiologic study of pesticide applicators and their spouses in Iowa and North Carolina. Exposure to targeted applied pest...
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AIRFLOW AROUND A CHILD-SIZE MANIKIN IN A LOW SPEED WIND ENVIRONMENT |
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This work provides an understanding of how airflow patterns around humans can affect the concentrations and particle size distributions of particulate matter (PM) in the breathing ...
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AMBIENT OZONE CAUSES UPPER AIRWAYS INFLAMMATION IN CHILDREN |
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Ozone constitutes a major air-pollutant in western Europe. uring the summer national air quality standards are frequently exceeded which justifies concern about the health effects ...
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AN ASTHMA INTERVENTION PILOT STUDY IN PUBLIC HOUSING: LESSONS AND BASELINE DATA |
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The paper reports baseline data and lessons learned about conducting asthma research in public housing. Nine families with asthmatic children living in a public housing developmen...
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AN EVALUATION OF INFANT EXPOSURE TO DIOXIN-LIKE COMPOUNDS IN BREAST MILK |
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A simple, one-compartment, first-order pharmacokinetic model is used to predict the infant body burden of dioxin-like compounds that results from breast-feeding. Validation testin...
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AN OBSERVATIONAL STUDY OF 127 PRESCHOOL CHILDREN AT THEIR HOMES AND DAYCARE CENTERS IN OHIO: ENVIRONMENTAL PATHWAYS TO CIS- AND TRANS-PERMETHRIN EXPOSURE |
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The potential exposures of 127 preschool children to the pyrethroid insecticides, cis- and trans-permethrin, in their everyday environments were examined. Participant...
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AN OBSERVATIONAL STUDY OF THE POTENTIAL EXPOSURES OF PRESCHOOL CHILDREN TO PENTACHLOROPHENOL, BISPHENOL-A, AND NONYLPHENOL AT HOME AND DAYCARE |
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The Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants (CTEPP) study investigated the potential exposures of 257 preschool children, ages 1 ...
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AN OVERVIEW OF THE NATIONAL CHILDREN'S STUDY |
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There is substantial public health concern that aspects of the environment adversely impact child health and development. Children may be more vulnerable to environmental threats ...
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ASSESSING ASTHMATIC CHILDREN'S EXPOSURES TO TOXIC AIR POLLUTANTS AND THE POTENTIAL INHALED DOSES USING TIME ACTIVITY INFORMATION AND ENERGY EXPENDITURE DATA |
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Accurately quantifying human exposures and the potential doses of various populations to environmental pollutants is critical for the U.S. Environmental Protection Agency to assess...
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ASSESSING CHILDREN'S EXPOSURES TO THE WOOD PRESERVATIVE CCA (CHROMATED COPPER ARSENATE) ON TREATED PLAYSETS AND DECKS |
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Concerns have been raised regarding the safety of young children contacting arsenic and chromium residues while playing on and around Chromated Copper Arsenate (CCA) treated wood...
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ASSESSMENT OF INDIVIDUAL HUMAN EXPOSURES TO OZONE IN A HEALTH STUDY |
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The minute dose of ozone delivered to the lower respiratory tract of a subject depends upon the ozone concentration inhaled, the minute volume (Ve 1/min) and the fraction of the in...
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ASSESSMENT OF YOUNG CHILDREN'S POTENTIAL PESTICIDE EXPOSURE FOLLOWING A RESIDENTIAL PESTICIDE APPLICATION - PART I. STUDY DESIGN: EXPOSURE OF CHILDREN AND TOYS |
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Semi-volatile pesticides such as chlorpyrifos can be dynamic in nature; once applied, they can migrate spatially and concentrations can build-up in and on objects and surfaces. ...
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ASSESSMENT OF YOUNG CHILDREN'S POTENTIAL PESTICIDE EXPOSURE FOLLOWING A RESIDENTIAL PESTICIDE APPLICATION. PART II - USE OF THE MACROACTIVITY APPROACH |
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Young children may be more susceptible to pesticides because they are undergoing rapid physiological and behavioral development. In addition, young children, as compared to adul...
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AVAILABLE MICRO-ACTIVITY DATA AND THEIR APPLICABILITY TO AGGREGATE EXPOSURE MODELING |
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Several human exposure models have been developed in recent years to address children's aggregate and cumulative exposures to pesticides under the Food Quality Protection Act of ...
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Air Pollution and Infant Mortality in Mexico City |
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Historic air pollution episodes of the 1950s led to acute increases in infant mortality, and some recent epidemiologic studies suggest that infant or child mortality may still resu...
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BLOOD LEAD, HEARING THRESHOLDS, AND NEUROBEHAVIORAL DEVELOPMENT IN CHILDREN AND YOUTH (JOURNAL VERSION) |
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NHANES II audiometry data were used to confirm a previously observed link between blood lead (PbB) level and hearing threshold. Other indicators of neurological development, such a...
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CAN FLU-LIKE ILLNESS BE AN INDICATION OF RECENT ORGANOPHOSPHATE PESTICIDE EXPOSURE IN PRESCHOOL CHILDREN? |
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Can flu-like illness be an indication of recent organophosphate pesticide exposure in preschool children? P Mendola*, D Barr, D Walsh, S Hern, S Rhoney, L Needham, E Hilborn, M Go...
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CASE STUDY: MULTIPOLLUTANT INDOOR AIR QUALITY STUDY OF 300 HOMESIN KINGSTON/HARRIMAN, TENNESSEE |
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An indoor air quality study of 300 homes in the Kingston/Harrimanarea of East Tennessee was conducted during 1985-86. his locationis one of six locations selected in a larger Harva...
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CHILD-SPECIFIC EXPOSURE FACTORS HANDBOOK (2008) |
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The National Center for Environmental Assessment Staff have prepared this handbook to provide information on various physiological and behavioral factors commonly used in assessing...
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CHILD-SPECIFIC EXPOSURE FACTORS HANDBOOK (EXTERNAL REVIEW DRAFT) 2000 |
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Children are often more heavily exposed to environmental toxicants than adults. They consume more food and water and have higher inhalation rates per pound of body weight than adul...
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CHILD-SPECIFIC EXPOSURE FACTORS HANDBOOK (EXTERNAL REVIEW DRAFT) 2006 |
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Children are often more heavily exposed to environmental toxicants than adults. They consume more food and water and have higher inhalation rates per pound of body weight than adul...
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CHILD-SPECIFIC EXPOSURE FACTORS HANDBOOK (INTERIM REPORT) 2002 |
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Children are often more heavily exposed to environmental toxicants than adults. They consume more food and water and have higher inhalation rates per pound of body weight than adu...
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CHILDHOOD RESPIRATORY SYMPTOMS, HOSPITAL ADMISSIONS, AND LONG-TERM EXPOSURE TO AIRBORNE PARTICULATE MATTER |
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The effects of long-term exposure to air pollution on respiratory symptoms and respiratory hospitalization (for asthma, bronchitis or pneumonia) were assessed in a cross-sectional ...
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CHILDREN'S DIETARY EXPOSURES TO CHEMICAL CONTAMINANTS |
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The Food Quality Protection Act of 1996 requires EPA to more accurately assess children's aggregate exposures to environmental contaminants. Children have unstructured eating beha...
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CHILDREN'S EXPOSURES TO ENDOCRINE DISRUPTING CHEMICALS |
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EPA is committed to protecting children's health by identifying, assessing, and reducing the risks from chemicals present in the air they breathe, food they eat, water they drink, ...
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CHILDREN'S RESIDENTIAL EXPOSURE TO CHLORPYRIFOS: APPLICATION OF CPPAES FIELD MEASUREMENTS OF CHLORPYRIFOS AND TCPY WITHIN MENTOR/SHEDS PESTICIDES MODEL |
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The comprehensive individual field-measurements on non-dietary exposure collected in the Children's-Post-Pesticide-Application-Exposure-Study (CPPAES) were used within MENTOR/SHEDS...
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CHLORPYRIFOS ACCUMULATION PATTERNS FOR CHILD ACCESSIBLE SURFACES AND OBJECTIVES AND URINARY METABOLITE EXCRETION BY CHILDREN FOR TWO-WEEKS AFTER CRACK-AND-CREVICE APPLICATION |
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The Children's-Post-Pesticide-Application-Exposure-Study (CPPAES) was conducted to look at the distribution of chlorpyrifos within a home environment for a 2-week period following ...
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COMMENTS ON "EFFECT OF PRENATAL EXPOSURE OF DELTAMETHRIN ON THE ONTOGENY OF XENOBIOTIC METABOLIZING CYTOCHROME P450S IN THE BRAIN AND LIVER OF OFFSPRINGS. |
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Comments on: Effect of prenatal exposure of deltamethrin on the ontogeny of xenobiotic metabolizing cytochrome P450s in the brain and liver of offsprings [Johri et al. Toxicol Appl...
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COMPARISON OF FIELD MEASUREMENTS FROM A CHILDREN'S PESTICIDE STUDY AGAINST PREDICTIONS FROM A PHYSICALLY BASED PROBABILISTIC MODEL FOR ESTIMATING CHILDREN'S RESIDENTIAL EXPOSURE AND DOSE TO CHLORPYRIFOS |
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Semi-volatile pesticides, such as chlorpyrifos, can move about within a home environment after an application due to physical/chemical processes, resulting in concentration loadi...
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CONCEPTUAL FRAMEWORK FOR CATEGORIZING YOUNG CHILDREN'S EATING BEHAVIORS |
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Recent studies of total dietary ingestion of common indoor contaminants have demonstrated that young children's behaviors while eating can lead to a significant source of food co...
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CONTRIBUTION OF CHLIDREN'S ACTIVITIES TO LEAD CONTAMINATION OF FOOD |
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This study evaluates the relationship of children's hygiene habits and food handling behaviors on lead levels on hands and handled foods for toddlers living in lead contaminated ho...
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CONTRIBUTIONS OF CHILDREN'S ACTIVITIES TO PESTICIDE HAND LOADINGS FOLLOWING RESIDENTIAL PESTICIDE APPLICATION |
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The role of children's activities in leading to pesticide exposure was evaluated by comparing pesticide loadings on the hands of children with the activities of the same children o...
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CREATION OF A GEOGRAPHIC INFORMATION SYSTEM TO IDENTIFY AT-RISK POPULATIONS IN NEW JERSEY AND NEW YORK FOR CONSUMPTION OF CONTAMINATED FISH AND SEAFOOD |
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Project Objective:
To identify at-risk populations, particularly women of child bearing years and young children, for consumption of contaminated fish and seafood via the use of g...
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CTEPP: RECRUITING AND FIELD SAMPLING IN NORTH CAROLINA AND OHIO |
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The research field study (CTEPP) of approximately 260 preschool children's exposures to persistent organic pollutants in their everyday environments began in early 2000. CTEPP i...
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DEFINING THE SPERMATOZOA RNA FINGERPRINT FOR THE NORMAL FERTILE MALE |
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Defining the spermatozoa RNA fingerprint for the normal fertile male
G. Charles Ostermeier1, David Dix2, David Miller3, and Stephen A. Krawetz1
1Departments of Ob/Gyn, ...
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DEMONSTRATION OF LOW COST BURDEN, EXPOSURE MONITORING STRATEGIES FOR USE IN LONGITUDINAL COHORT STUDIES - VOLUME I - FINAL REPORT AND VOLUME II - APPENDICES |
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The Federal Government is currently planning a large, prospective birth cohort study known as the National Children's Study that will potentially involve 100,000 children and their...
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DEMONSTRATION OF LOW COST, LOW BURDEN EXPOSURE MONITORING STRATEGIES FOR USE IN LONGITUDINAL COHORT STUDIES |
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A large longitudinal cohort study designed to evaluate the association between children's exposures to environmental agents and health outcomes presents many challenges for expos...
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DETERMINATION OF A STANDARD FOOD ITEM FOR ANALYSIS OF PESTICIDE CONSUMPTION IN THE DIETARY INTAKE OF YOUNG CHILDREN |
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The objective of this study was to establish a standard food item for the collection of residential use pesticides from household surfaces commonly encountered by young children wh...
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DETERMINATION OF ROUTES OF EXPOSURE OF INFANTS AND TODDLERS TO HOUSEHOLD PESTICIDES: A PILOT STUDY |
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The U.S. EPA recently completed a study of nonoccupational exposure to household pesticides. uring that study, house dust and yard soil were recognized to be potential major source...
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DEVELOPMENT OF A BIOMARKERS DATABASE FOR THE NATIONAL CHILDREN'S STUDY, PROCEEDINGS TO BE PUBLISEHD FROM THE INTERNATIONAL CONFERENCE ON BIOMARKERS FOR TOXICOLOGY AND MOLECULAR EPIDEMIOLOGY, ATLANTA, GA, MARCH 15-17, 2004 |
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The National Children's Study (NCS) is a federally-sponsored, longitudinal study of environmental influences on the health and development of children across the United States (www...
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DEVELOPMENT OF EXPOSURE ASSESSMENT STUDY DESIGN FOR THE NATIONAL CHILDREN'S STUDY (NCS) |
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The general plan for the exposure monitoring component of the planned National Children's Study (NCS) is to measure indoor and outdoor concentrations and personal exposures for ...
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DIETARY EXPOSURE FROM PESTICIDE APPLICATION ON FARMS IN THE AGRICULTURAL HEALTH PILOT STUDY |
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As part of total human exposure measurements performed on six farms in Iowa and North Carolina during the Agricultural Health Pilot Study, a household duplicate diet, several local...
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DIETARY EXPOSURE OF CHILDREN IN LEAD-LADEN ENVIRONMENTS |
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Children are the most susceptible population to lead exposure because of three interacting factors; they have more opportunity for contact with lead sources due to their activities...
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DIETARY EXPOSURE OF CHILDREN LIVING IN LEAD-LADEN ENVIRONMENTS |
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Children are the most susceptible population to lead exposure because of three interacting factors: they have more opportunity for contact with lead sources due to their activities...
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DIETARY EXPOSURE OF CHILDREN TO LEAD |
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Children are the most susceptible population to lead exposure because 1) they have more opportunity for contact with lead sources due to their activities, 2) lead adsorption occurs...
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DIETARY EXPOSURES OF YOUNG CHILDREN, PART 1: MODEL DEVELOPMENT AND STUDY DESIGN |
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Young children contact surfaces (hands, floors, etc.) that may be contaminated with pesticides. Thus, dietary exposures of young children are difficult to measure, but are needed t...
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DIETARY EXPOSURES OF YOUNG CHILDREN, PART 3: MODELLING |
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A deterministic model was used to model dietary exposure of young children. Parameters included pesticide residue on food before handling, surface pesticide loading, transfer effic...
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DIETARY EXPOSURES OF YOUNG CHILDREN, PART II: FIELD STUDY |
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A small, pilot field study was conducted to determine the adequacy of protocols for dietary exposure measurements. Samples were collected to estimate the amount of pesticides tran...
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DIRECT OBSERVATION OF NEIGHBORHOOD ATTRIBUTES IN AN URBAN AREA OF THE US SOUTH: CHARACTERIZING THE SOCIAL CONTEXT OF PREGNANCY |
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BACKGROUND: Neighborhood characteristics have been associated with poor maternal and child health outcomes, yet conceptualization of potential mechanisms is still needed. Census da...
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DISTRIBUTION OF 2,4-DICHLOROPHENOXYACETIC ACID IN FLOOR DUST THROUGHOUT HOMES FOLLOWING HOMEOWNER AND COMMERICAL LAWN APPLICATIONS: QUANTITATIVE EFFECTS OF CHILDREN, PETS, AND SHOES |
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Transport of lawn-applied 2,4-D into 13 actual homes was measured following both homeowner and commercial application of this herbicide to residential lawns. Collection of floor ...
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DISTRIBUTION OF FORCED VITAL CAPACITY AND FORCED EXPIRATORY VOLUME IN ONE SECOND IN CHILDREN 6 TO 11 YEARS OF AGE |
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The authors analyzed 44,664 annual measurements of forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) in 12,258 white children and 1,041 black children b...
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Dosimetry of nasal uptake of soluble and reactive gases: A first study of inter-human variability |
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Anatomically accurate human child and adult nasal tract models will be used in concert with computationally simulated air flow information to investigate the influence of age-relat...
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EFFECT OF BODY SIZE ON BREATHING PATTERN AND FINE PARTICLE DEPOSITION IN CHILDREN |
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Inter-child variability in breathing patterns may contribute to variability in fine particle, lung deposition and morbidity in children associated with those particles. Fractional ...
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EFFECT OF LOW-LEVEL LEAD EXPOSURE ON PEDIATRIC NEUROBEHAVIORAL AND PHYSICAL DEVELOPMENT: CURRENT FINDINGS AND FUTURE DIRECTIONS |
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Studies of the relationship between lead exposure and the physical and neurobehavioral development of children constitute an important part of the scientific foundation for regulat...
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EFFECTS OF AMBIENT SULFUR OXIDES AND SUSPENDED PARTICLES ON RESPIRATORY HEALTH OF PREADOLESCENT CHILDREN |
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The paper reports results from an ongoing study of outdoor air pollution and respiratory health status of children living in six cities in the eastern and midwestern United States....
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ENDOCRINE EFFECTS OF PRENATAL EXPOSURES TO PCBS, DIOXINS, AND OTHER XENOBIOTICS: IMPLICATIONS FOR POLICY AND FUTURE RESEARCH |
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Recent reports have suggested that environmental chemicals may be associated with endocrine alterations in people, wildlife, and experimental animals. harmacological investigations...
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ENVIRONMENTAL MEASUREMENTS OF ORGANOPHOSPHATE AND PYRETHROID PESTICIDES TO ASSESS EXPOSURES OF YOUNG CHILDREN LIVING IN JACKSONVILLE, FL |
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The Duval County Health Department (DCHD, Jacksonville, FL), in collaboration with the Centers for Disease Control and Prevention (CDC) and the US Environmental Protection Agency...
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ENVIRONMENTAL PCB AND PESTICIDE EXPOSURE AND RISK OF ENDOMETRIOSIS |
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Environmental PCB and Pesticide Exposure and Risk of Endometriosis
Germaine M. Buck1, John M. Weiner2, Hebe Greizerstein3, Brian Whitcomb1, Enrique Schisterman1, Paul Kostyn...
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ESTIMATING CHILDREN'S DERMAL AND NON-DIETARY INGESTION EXPOSURE AND DOSE WITH EPA'S SHEDS MODEL |
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A physically-based stochastic model (SHEDS) has been developed to estimate pesticide exposure and dose to children via dermal residue contact and non-dietary ingestion. Time-loca...
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ESTIMATING CONTAMINANT DOSE FOR INTERMITTENT DERMAL CONTACT: MODEL DEVELOPMENT, TESTING, AND APPLICATION |
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Assessments of aggregate exposure to pesticides and other surface contamination in residential environments are often driven by assumptions about dermal contacts. Accurately predic...
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ESTIMATING EXCESS DIETARY EXPOSURES OF YOUNG CHILDREN |
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Nine children in a daycare that routinely applied the pesticide, esfenvalerate, were studied to assess excess dietary exposures. Surface wipes, a standard food item of processed A...
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EVALUATING COMMERCIALLY AVAILABLE DERMAL WIPES, COTTON SUITES, AND ALTERNATIVE URINARY COLLECTION MATERIALS FOR PESTICIDE SAMPLING FROM INFANTS |
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As the Human Exposure Program focuses on the exposure of children to pesticides, there are concerns about the effect, or perceived effect, of components of the sampling procedure o...
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EVALUATING EXCESS DIETARY EXPOSURE OF YOUNG CHILDREN EATING IN CONTAMINATED ENVIRONMENTS |
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The United States' Food Quality Protection Act of 1996 requires more accurate assessment of children's aggregate exposures to environmental contaminants. Since children have uns...
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EXPLORATION OF PERINATAL PHARMACOKINETIC ISSUES |
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In the process of reviewing current Agency toxicology testing paradigms for hazard characterization, the Risk Assessment Forum's (Forum) Reference Dose (RfD) Technical Panel became...
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EXPOSURE ASSESSMENT FINDINGS FROM THE TAMPA ASTHMATIC CHILDREN'S STUDY (TACS) |
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The Tampa Asthmatic Children's Study (TACS) was a pilot study that focused on developing and evaluating air pollution exposure assessment methods and participant recruiting tools...
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EXPOSURE ASSESSMENT IMPLICATIONS FOR THE DESIGN AND IMPLEMENTATION OF THE NATIONAL CHILDREN'S STUDY |
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Examining the influence of environmental exposures on various health indices is a critical component of the planned National Children¿s Study (NCS). An ideal strategy for the expos...
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EXPOSURE FACTORS PROGRAM |
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The development of the latest version of the Exposure Factors Handbook 1997(EPA/600/P-95/Fa, Fb, and Fc) has brought to light the need for a more comprehensive ...
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EXPOSURES OF PRESCHOOL CHILDREN TO PENTACHLOROPHENOL, BISPHENOL-A, AND NONYLPHENOL AT HOME AND DAYCARE |
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The Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants (CTEPP) study investigated the potential exposures of 257 preschool children and thei...
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EXPOSURES TO ACIDIC AEROSOLS |
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Ambient monitoring of acid aerosol in four U.S. cities and in a rural region of southern Ontario clearly show distinct periods of strong acidity. easurements made in Kingston, TN, ...
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FACTORS INFLUENCING TOTAL DIETARY EXPOSURE OF YOUNG CHILDREN |
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A deterministic model was developed to identify critical input parameters to assess dietary intake of young children. The model was used as a framework for understanding important ...
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FACTORS INFLUENCING TOTAL DIETARY EXPOSURES OF YOUNG CHILDREN |
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A deterministic model was developed to identify the critical input parameters needed to assess dietary intakes of young children. The model was used as a framework for understandi...
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FEASIBILITY STUDY OF THE POTENTIAL FOR HUMAN EXPOSURE TO PET-BORNE DIAZINON RESIDUES FOLLOWING LAWN APPLICATIONS |
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Diazinon (O,O-diethyl-O-[2-isopropyl-6-methylpyrimidin-4-yl]phosphorothioate) is a broad spectrum organophosphorus insecticide commonly used to control a variety of pest insects ...
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FINAL REPORT, USE OF 1) SENSORS AND 2)RADIO FREQUENCY ID (RFID) FOR THE NATIONAL CHILDREN'S STUDY |
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Recent advancements in technology have provided new tools that researchers can use to collect data more easily and reduce participant burden. In what ways will this new technology ...
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FINAL REPORT: NATIONAL CHILDREN'S STUDY FOCUS GROUPS - FOLLOW-UP |
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The purpose of this work assignment was to add to our knowledge of the issues that will affect
recruitment and retention of pregnant women into the National Children's Study...
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FLOW AND AEROSOL TRANSPORT AROUND A CHILD-SIZE MANIKIN |
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There is no abstract available for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact field....
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FOCUSING ON CHILDREN’S INHALATION DOSIMETRY AND HEALTH EFFECTS FOR RISK ASSESSMENT: AN INTRODUCTION |
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Substantial effort has been invested in improving children’s health risk assessment in recent years. However, the body of scientific evidence in support of children’s health asses...
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FREQUENCY OF MOUTHING BEHAVIOR IN YOUNG CHILDREN |
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Young children may be more likely than adults to be exposed to pesticides following a residential application as a result of hand- and object-to-mouth contacts in contaminated ar...
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FREQUENCY OF MOUTHING BEHAVIOR IN YOUNG CHILDREN |
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Young children, as compared to adults, are more likely to be exposed after a pesticide application due to potential hand- and object-to-mouth contacts in contaminated areas. How...
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GUIDANCE ON SELECTING AGE GROUPS FOR MONITORING AND ASSESSING CHILD-HOOD EXPOSURES TO ENVIRONMENTAL CONTAMINANTS (FINAL) |
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A major issue facing the Agency is how to consistently consider age-related changes in behavior and physiology when assessing early lifestage exposure and potential dose. Key to t...
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HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE'S EXPOSURE FACTORS DATABASE FOR AGGREGATE AND CUMULATIVE RISK ASSESSMENT |
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In recent years, the risk analysis community has broadened its use of complex aggregate and cumulative residential exposure models (e.g., to meet the requirements of the 1996 Food ...
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HESI EXPOSURE FACTORS DATABASE FOR AGGREGATE AND CUMULATIVE RISK ASSESSMENT |
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In recent years, the risk analysis community has broadened its use of complex aggregate and cumulative residential exposure models (e.g., to meet the requirements of the 1996 Foo...
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HUMAN ROTAVIRUS STUDIES IN VOLUNTEERS: DETERMINATION OF INFECTIOUS DOSE AND SEROLOGICAL RESPONSE TO INFECTION |
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An unpassaged, safety-tested strain of human rotavirus, obtained from a stool specimen of a hospitalized child (CJN), was administered orally to 62 adult volunteers to determine th...
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HYGIENE-AND FOOD-RELATED BEHAVIORS ASSOCIATED WITH BLOOD LEAD LEVELS OF YOUNG CHILDREN FROM LEAD-CONTAMINATED HOMES |
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Exposures associated with blood lead levels greater than 40 ug/dl in young children who live in lead-contaminated homes have been well documented. As the action level for lead is r...
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IDENTIFYING RECRUITMENT AND RETENTION ISSUES FOR THE NATIONAL CHILDREN'S STUDY |
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Recruitment and Retention Issues for the National Children's Study
Danelle T Lobdell1, Suzanne Gilboa2, Pauline Mendola1 (1US EPA, NHEERL; 2UNC Chapel Hill)
A better unde...
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IN UTERO ENVIRONMENTAL EXPOSURES IN THE NATIONAL CHILDREN'S STUDY - MEASUREMENT STRATEGIES |
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The National Children¿s Study (NCS) is a longitudinal cohort study which is designed to follow a nationally representative sample of American children from prior to conception or e...
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INDOOR AIR POLLUTION AND PULMONARY FUNCTION GROWTH IN PREADOLESCENT CHILDREN |
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Results are reported from a study of the association between exposure to sidestream cigarette smoke or gas stove emissions and pulmonary function level and growth rate of 7,834 chi...
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INTERIM RESULTS FROM THE AGRICULTURAL HEALTH STUDY/PESTICIDE EXPOSURE STUDY |
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The Agricultural Health Study (AHS) is a prospective epidemiological study of pesticide applicators and their spouses in Iowa and North Carolina. Exposure to 2,4-D or chlorpyrif...
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INTRODUCTION TO PHYTOTECHNOLOGIES |
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A tree is a tree is a tree; or is it? To a child a tree is to climb, to a landscape architect a tree shapes the view, while to an environmental engineer a tree may be a self-assem...
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Influence of Activity on Transfer of Pesticides from Treated Formica ® in Foods |
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The children’s dietary intake model (CDIM) has been developed to predict total dietary intake of a child incorporating excess exposures due to handling of food prior to consumption...
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LEAD IN CANDLE EMISSIONS |
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The candle-using public should be made aware that the core of candle wicks may contain lead. Used as a stiffening agent to keep the wick out of the molten wax, lead can be emitted ...
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LEVELS OF ORGANOCHLORINE, ORGANOPHOSPHATE, AND PYRETHROID PESTICIDES IN CTEPP NORTH CAROLINA MULTIMEDIA SAMPLES |
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CTEPP (Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants) is a pilot study of the possible exposures of 257 preschool children and their ...
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LONGITUDINAL STUDY OF YOUNG CHILDREN'S EXPOSURES IN THEIR HOMES TO SELECTED PESTICIDES, PHTHALATES, BROMINATED FLAME RETARDANTS, AND PERFLUORINATED CHEMICALS (A CHILDREN'S ENVIRONMENTAL EXPOSURE RESEARCH STUDY - CHEERS) |
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The U.S. Environmental Protection Agency's (EPA) National Exposure Research Laboratory (NERL) is conducting a study of young children's exposures to chemicals in the home. The Ame...
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LOWER PREVALENCE OF ASTHMA AND WHEEZE AMONG HISPANIC CHILDREN ALONG HTE U.S. MEXICO BORDER |
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Lower Prevalence of Asthma and Wheeze Among Hispanic Children Along the U.S. Mexico Border. Melissa Gonzales, Debra Walsh, Scott Rhoney, Lucas M. Neas. US EPA, ORD, NHEERL, Resear...
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MATERNAL-FETAL TISSUE LEVELS OF SIXTEEN TRACE ELEMENTS IN EIGHT COMMUNITIES |
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The developing fetus probably represents one of the most vulnerable subgroups of the general population to the toxic effects of trace elements. There have been numerous reports of ...
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MEASUREMENT OF CHILDREN'S EXPOSURE TO PESTICIDES: ANALYSIS OF URINARY METABOLITE LEVELS IN A PROBABILITY-BASED SAMPLE |
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The Minnesota Children's Pesticide Exposure Study is a probability-based sample of 102 children 3-13 years old who were monitored for commonly used pesticides. During the summer...
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MEASUREMENTS OF TRANSFERRABLE RESIDUE FROM CERAMIC TILE, VINYL TILE, HARDWOOD FLOORING, AND CARPET USING A PRESS SAMPLER AND C18, PUF, AND COTTON SAMPLING DISKS |
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Unintentional and avoidable human exposure is a consequence of pesticide use indoors. Pesticides on household surfaces are a source of exposure to children. Therefore, concern ha...
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MEASURING DIETARY EXPOSURE OF YOUNG CHILDREN |
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Young children do not consume foods in a structured manner. Their foods contact surfaces (hands, floors, eating surfaces, etc.) that may be contaminated while they are eating them...
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MEASURING EXCESS DIETARY EXPOSURES CAUSED BY EATING ACTIVITIES OF YOUNG CHILDREN |
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A small, pilot field study was conducted to measure dietary exposures of young children which included contamination of foods while eating. Samples were collected to estimate the ...
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METHODS ADVANCEMENT FOR MILK ANALYSIS: THE MAMA STUDY |
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The Methods Advancement for Milk Analysis (MAMA) study was designed by US EPA and CDC investigators to provide data to support the technological and study design needs of the propo...
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METHODS STUDIES FOR THE NATIONAL CHILDREN'S STUDY: MOLECULARLY IMPRINTED POLYMERS |
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Accurate exposure classification tools are required to link exposure with health effects in epidemiological studies. Although long-term integrated exposure measurements are a cri...
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METHODS STUDIES FOR THE NATIONAL CHILDREN'S STUDY: SEMIPERMEABLE MEMBRANE DEVICE (SPMD) |
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Accurate exposure classification tools are required to link exposure with health effects in epidemiological studies. Although long-term integrated exposure measurements are a cri...
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MITE ANTIGEN CONCENTRATIONS IN HOUSE DUST AND THE OCCURRENCE OF WHEEZING IN CHILDREN WITH MITE DUST ALLERGY |
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We studied the relationship between dust mite antigen concentrations in house dust samples and the occurrence and frequency of wheezing in 58 children with dust mite allergy (wheal...
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MODELING AGGREGATE CHLORPYRIFOS EXPOSURE AND DOSE TO CHILDREN |
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To help address the aggregate exposure assessment needs of the Food Quality Protection Act, a physically-based probabilistic model (SHEDS-Pesticides, version 3) has been applied ...
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MODELING APPROACHES FOR ESTIMATING THE DOSIMETRY OF INHALED TOXICANTS IN CHILDREN |
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Risk assessment of inhaled toxicants has typically focused upon adults, with modeling used to extrapolate dosimetry and risks from laboratory animals to humans. However, behaviora...
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MODELING OF MACROSCALE AGRICULTURAL ELEMENTS IN PESTICIDE EXPOSURE |
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Yuma County, Arizona, is the site of year around agriculture. To understand the role of agricultural pesticide exposures experienced by children, urinary metabolite concentratio...
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MOLECULAR ANALYSIS OF HUMAN SPERMATOZOA: POTENTIAL FOR INFERTILITY RESEARCH |
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Gordon Research Conference: Mammalian Gametogenesis and Embryogenesis
New London, CT, July 1-6, 2000
Molecular Analysis of Human Spermatozoa:
Potential for Infertili...
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MOLECULAR ANALYSIS OF HUMAN SPERMATOZOA: POTENTIAL FOR INFERTILITY RESEARCH AND SCREENING |
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Molecular Analysis of Human Spermatozoa: Potential for Infertility Research and Screening
David Miller1, David Dix2, Robert Reid3, Susan Wykes3 and Stephen Krawetz3
1Reprodu...
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MORPHOMETRIC COMPARISON OF NASOPHARYNGEAL AIRWAY OF LABORATORY ANIMALS AND THE HUMAN |
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Solid silicone rubber casts of the nasopharyngeal and laryngeal regions of a human cadaver (child, three years old) and a laboratory primate (baboon, 10 years old) were made and cr...
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MORPHOMETRIC STUDY OF NASAL-PHARYNGEAL GROWTH FOR PARTICLE DEPOSITION IN RAT |
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Deposition data for a potentially susceptible subpopulation such as adolescents are needed, as well as dosimetry models that can account for variables important to a subpopulation....
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MOVEMENT AND DEPOSITION OF PESTICIDES WITHIN RESIDENCES AFTER INTERIOR AND EXTERIOR APPLICATIONS |
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In a study begun in 1999, the Environmental Protection Agency (EPA) investigated the temporal and spatial distributions of pesticides applied by homeowners and commercial applica...
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MOVEMENT AND DEPOSITION OF TWO ORGANOPHOSPHORUS PESTICIDES WITHIN A RESIDENCE AFTER INTERIOR AND EXTERIOR APPLICATIONS |
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Post-application temporal and spatial distributions of two organophosphorus pesticides, diazinon and chlorpyrifos, were monitored after homeowner applications for indoor and outd...
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NATIONAL SURVEYS OF MULTIPLE ENVIRONMENTAL HAZARDS TO YOUNG CHILDREN IN HOMES AND CHILD CARE CENTERS |
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The Department of Housing and Urban Development (HUD) has teamed with other federal agencies to characterize exposure of multiple environmental hazards to young children in two m...
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NCS TECHNOLOGY WORKSHOP & REPORT |
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Innovative Technologies for Remote Collection of DataMay 12-14, 2003Hyatt Harborside HotelBoston, MAThis meeting was held in conjunction with...
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NERL'S QUEST TO REDUCE UNCERTAINTIES IN CHILDREN'S HEALTH AND RISK ASSESSMENTS |
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Data on children's exposure to chemical contaminants and their activities are very limited. Quantitative assessments rely heavily on major default assumptions as substitutes for...
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NEUROTOXICOLOGY IN THE FETUS AND CHILD: CONFERENCE SUMMARY |
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The stated objective of the conference, 'Neurotoxicology in the Fetus and Child', was to present papers and focus discussions on both clinical and experimental issues related to th...
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NHEXAS PHASE I REGION 5 STUDY--STANDARD OPERATING PROCEDURE--DUST SAMPLING WORKPLAN (RTI/ACS-AP-209-020) |
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This procedure describes the work plan for collecting house dust samples. Wipe samples were collected to determine the concentrations (ug/g) and loadings (ug/cm2) of trace metals i...
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NTP-CERHR EXPERT PANEL REPORT ON REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF METHYLPHENIDATE. |
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A manuscript describes the results of an expert panel meeting of the NTP Center for the Evaluation of Risks to Human Reproduction (CERHR). The purpose CERHR is to provide timely, ...
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NTP-CERHR EXPERT PANEL REPORT ON THE REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF AMPHETAMINE AND METHAMPHETAMINE. |
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A manuscript describes the results of an expert panel meeting of the NTP Center for the Evaluation of Risks to Human Reproduction (CERHR). The purpose CERHR is to provide timely...
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Neighborhood factors associated with physical activity and adequacy of weight gain during pregnancy |
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Healthy diet, physical activity, smoking, and adequate weight gain are all associated with maternal health and fetal growth during pregnancy. Neighborhood characteristics have been...
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ON THE IMPACT OF THE HUMAN (CHILD) MICROCLIMATE ON PASSIVE AEROSOL MONITOR PERFORMANCE |
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Research into the wind microclimate and its effect on the accuracy and effectiveness of passive aerosol monitors is expanding as the importance of personal monitoring versus regi...
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PAH CONCENTRATIONS IN MULTIPLE MEDIA AT THE HOMES AND CHILD DAY CARE CENTERS OF 130 NORTH CAROLINA CHILDREN |
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In the late summer of 2000 and the early spring of 2001, in the USEPA-sponsored program, "Children's Total Exposures to Persistent Pesticides and Other Persistent Organic Po...
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PAIRED-CITY STUDY TO DETERMINE THE CONTRIBUTION OF SOURCE WATER TYPE TO THE ENDEMIC LEVEL OF MICROBIAL DISEASE |
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Paired-City Study to Determine the Contribution of Source Water Type to the Endemic Level of Microbial Disease
F Frost PhD, T Kunde MPH, L Harter PhD, T Muller MS, GF Craun ...
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PARENTAL ALLERGY TO FARM ALLERGENS NAD ALLERGIC ILLNESSES IN CHILDREN |
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Recent literature has reported low asthma and/or atopy prevalence or associated symptoms in rural/agricultural populations. We found relatively high rates of childhood asthma (16%)...
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PASSIVE SMOKING AND HEIGHT GROWTH OF PREADOLESCENT CHILDREN |
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The attained height and height growth of 9273 children participating in a longitudinal study of the health effects of air pollutants were analyzed to assess the association between...
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PASSIVE SMOKING, GAS COOKING, AND RESPIRATORY HEALTH OF CHILDREN LIVING IN SIX CITIES |
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As part of a longitudinal study of the respiratory health effects of indoor and outdoor air pollutants, pulmonary function, respiratory illness history, and symptom history were re...
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PERSISTENCE OF PEAK FLOW DECREMENT IN CHILDREN FOLLOWING OZONE EXPOSURES EXCEEDING THE NATIONAL AMBIENT AIR QUALITY STANDARD |
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Spironmetric measurements of lung function were made on six or more occasions over a five week period in 1982 in 39 children attending a summer day camp in Mendham, N.J. Mean slope...
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PESTICIDE EXPOSURE AND IMMUNE FUNCTION AMONG TODDLERS |
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Response to vaccination may be a sensitive indicator of immunollogic health in young children. Toddlers residing in an intenseive agricultural area along the US/Mexican border w...
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PESTICIDE EXPOSURE AND POTENTIAL HEALTH EFFECTS IN YOUNG CHILDREN ALONG THE U.S. - MEXICO BORDER |
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The purpose of the Pesticides in Young Children - Border States Program is to assess the relationship between health status in children living along the United States and Mexico bo...
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PESTICIDE MEASUREMENT RESULTS FROM THE FIRST NATIONAL ENVIRONMENTAL SURVEY OF CHILD CARE CENTERS |
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Approximately 13 million children are placed in non-parental child care during the work day; however, children's exposures to chemicals in child care centers have not been characte...
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PESTICIDE MEASUREMENTS FROM THE FIRST NATIONAL ENVIRONMENTAL HEALTH SURVEY OF CHILD CARE CENTERS USING A MULTI-RESIDUE GC/MS ANALYSIS METHOD |
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The US Department of Housing and Urban Development, in collaboration with the US Consumer Product Safety Commission and the US Environmental Protection Agency, characterized the en...
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PESTICIDE RESULTS FROM AN INTERAGENCY EFFORT TO CHARACTERIZE CONTAMINANTS IN CHILD CARE CENTERS |
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Approximately 13 million children are placed in non-parental child care during the work day; but, children's exposures to chemicals in child care centers have not been characteri...
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PESTICIDE SURFACE RESIDUE MEASUREMENTS BY A PRESS SAMPLER |
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Pesticides on household surfaces are a source of exposure to children. Accurate measurements of residues on surfaces are needed to determine amounts available for transfer to food...
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PESTICIDES AND THEIR METABOLITES IN THE HOMES AND URINE OF FARMWORKER CHILDREN LIVING IN THE SALINAS VALLEY, CA |
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This paper describes a study to test field methods for characterizing pesticide exposures to 20 farmworker children aged 5-27 months old living in the Salinas Valley of Monterey Co...
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PESTICIDES IN DUST SAMPLES FROM HOMES AND SCHOOLS IN YUMA, ARIZONA |
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A pilot study was conducted in Yuma, Arizona to investigate children's exposure to pesticides as detected in urine and dust samples. The principle hypothesis of the study is that...
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PILOT STUDY PROTOCOL: APPLICATION OF MEASURES OF SPONTANEOUS MOTOR ACTIVITY FOR BEHAVORIAL ASSESSMENT IN HUMAN INFANTS |
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As a participant in planning the National Childrens Study (NCS), EPA is interested in the investigation of key developmental disorders that may be associated with environmental exp...
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PILOT STUDY: THE TAMPA ASTHMATIC CHILDREN'S STUDY (TACS) |
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The Tampa Asthmatic Children's Study (TACS) was a pilot research study that focused on developing and evaluating air pollution exposure assessment methods and participant recruitin...
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POST-APPLICATION EXPOSURE POTENTIAL TO PESTICIDES IN THE RESIDENTIAL ENVIRONMENT |
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A study to investigate the temporal and spatial distributions of pesticides applied by homeowners and commercial applicators for indoor crack and crevice treatments was initiated...
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PRELIMINARY EXPOSURE ASSESSMENT FINDINGS FROM THE TAMPA ASTHMATIC CHILDREN'S STUDY |
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The Tampa Asthmatic Children's Study (TACS) was a pilot study that focused on developing and evaluating air pollution exposure assessment methods and participant recruiting tools...
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PROTECTING OUR CHILDREN FROM HARM: MEASURING ENVIRONMENTAL RISKS TO CHILDREN REQUIRES UNDERSTANDING THEIR UNIQUE MEANS OF EXPOSURE |
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Children's exposures to consumer products and environmental contaminants are expected to be different and, in some cases, much higher than adult's exposures. The objectives of o...
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QUANTIFICATION OF SIDEROPHORE AND HEMOLYSIN FROM STACHYBOTRYS CHARTARUM STRAINS, INCLUDING A STRAIN ISOLATED FROM THE LUNG OF A CHILD WITH PULMONARY HEMORRHAGE AND HEMOSIDEROSIS |
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A strain of Stachybotrys chartarum was recently isolated from the lung of a pulmonary hemorrhage and hemosiderosis (PH) patient in Texas (designated the Houston strain). This is th...
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QUANTITATIVE ESTIMATES OF SOIL INGESTION IN NORMAL CHILDREN BETWEEN THE AGES OF 2 AND 7 YEARS: POPULATION-BASED ESTIMATES USING ALUMINUM, SILICON, AND TITANIUM AS SOIL TRACER ELEMENTS |
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This investigation was undertaken to provide quantitative estimates of soil ingestion in young children on a population basis, and to identify demographic and behavioral characteri...
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QUANTITATIVE PCR ANALYSIS OF FUNGI IN DUST FROM HOMES OF INFANTS WHO DEVELOPED IDIOPATHIC PULMONARY HEMORRHAGING |
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Fungal concentrations were measured in the dust of six homes in Cleveland, OH, where a child developed pulmonary hemorrhage (pulmonary hemorrhage homes, i.e. PHH), and 26 reference...
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RECRUITING FOR A LONGITUDINAL STUDY OF CHILDREN'S HEALTH USING A HOUSEHOLD-BASED PROBABILITY SAMPLING APPROACH |
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The sampling design for the National Children¿s Study (NCS) calls for a population-based, multi-stage, clustered household sampling approach (visit our website for more information...
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RECRUITING, RETAINING, AND REPORTING EXPOSURE STUDY RESULTS TO PARTICIPANTS AND THE PUBLIC |
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EPA's National Exposure Research Laboratory (NERL) is developing techniques and capabilities to recruit and retain participants in exposure measurement studies and to effectively...
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RECRUITMENT AND RETENTION ISSUES FOR A LONGITUDINAL STUDY OF CHILDREN'S ENVIRONMENTAL HEALTH |
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A better understanding of the most effective recruitment techniques and retention strategies for longitudinal, community-based, children's environmental health studies is needed. ...
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RECRUITMENT AND RETENTION ISSUES FOR THE NATIONAL CHILDREN'S STUDY |
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A better understanding of the most effective recruitment techniques and retention strategies for longitudinal, community-based, children's environmental health studies is needed. ...
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RELATIONSHIP BETWEEN FINE AND ULTRAFINE PARTICLE NUMBER AND VOC SPECIES IN EL PASO, TEXAS |
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Children's exposures to consumer products and environmental contaminants are expected to be different and, in some cases, much higher than adult's exposures. The objectives of o...
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RELATIONSHIP OF LATE POSITIVE ERPS (EVENT-RELATED POTENTIALS), AGE, INTELLIGENCE AND LEAD ABSORPTION IN SOCIOECONOMICALLY DISADVANTAGED CHILDREN |
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Children from socioeconomically disadvantaged families are at risk for malnutrition, learning disabilities, and many other problems associated with poverty. Increasing application ...
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RELATIONSHIPS BETWEEN QUESTIONNAIRE RESPONSES AND CHILDREN'S PESTICIDE EXPOSURE MEASUREMENTS |
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The objective of this project is to identify questions that indicate a higher likelihood of predicting a child's level of exposure to pesticides as input to future study designs....
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RELATIONSHIPS OF METALS IN FLOOR DUST AND ON THE HANDS OF TODDLERS |
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Toddlers are characterized by their frequent hand-to-mouth activity and exploratory behavior. This puts them at risk for exposure to environmental contaminants. Wipe samples are tr...
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RESEARCH IN EPA'S NATIONAL EXPOSURE RESEARCH LABORATORY (NERL) TO REDUCE UNCERTAINTIES IN CHILDREN'S EXPOSURE/RISK ASSESSMENTS |
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The US EPA has pledged to increase its efforts to provide a safe and healthy environment for children by ensuring that all EPA regulations, standards, policies, and risk assessme...
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RESIDENTIAL PESTICIDE USE AND URINARY ORGANOPHOSPHATE METABOLITES IN PRE-SCHOOL CHILDREN |
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Residential Pesticide Use and Urinary Organophosphate Metabolites in Pre-School Children
CL Carty1, P Mendola1, D Barr2, L Needham2, D Walsh1
1Epidemiology and Biomarkers...
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RESPIRATORY DAMAGE IN CHILDREN EXPOSED TO URBAN POLLUTION |
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Southwest Metropolitan Mexico City (SWMMC) children are chronically exposed to complex mixtures of air pollutants. In a cross-sectional arm of our study, we investigated the as...
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RESULTS FROM THE AHS PESTICIDE EXPOSURE STUDY |
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The Agricultural Health Study/Pesticide Exposure Study (AHS/PES) measured exposures resulting from agricultural use of 2,4-D and chlorpyrifos for a subset of applicators in the A...
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SEPARATING THE EFFECTS OF LEAD AND SOCIAL FACTORS ON IQ |
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Initial evaluations of 104 low-socioeconomic status black children screened by the local community health departments in North Carolina showed significant effects of lead in the ra...
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SOURCE APPORTIONMENT OF INDOOR, OUTDOOR, AND PERSONAL PM2.5 IN SEATTLE, WASHINGTON, USING POSITIVE MATRIX FACTORIZATION |
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As part of a large exposure assessment and health effects panel study, 33 trace elements and light-absorbing carbon were measured on 24-hr particulate matter with an aero-dynamic d...
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STOCHASTIC HUMAN EXPOSURE AND DOSE SIMULATION MODEL FOR THE WOOD PRESERVATIVE SCENARIO (SHEDS-WOOD), VERSION 2 MODEL SAS CODE |
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Concerns have been raised regarding the safety of young children contacting arsenic and chromium residues while playing on and around Chromated Copper Arsenate (CCA) treated wood p...
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STUDIES OF PRESCHOOL CHILDREN'S EXPOSURES TO PERSISTENT PESTICIDES |
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Young children may have greater exposures than do older children or adults to some persistent organic pesticides, because of differences in their diet and activities. The physic...
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STUDY DESIGN CONSIDERATIONS FOR THE EXPOSURE COMPONENT OF THE NATIONAL CHILDREN'S STUDY |
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An ideal strategy for the exposure monitoring component of the planned National Children's Study (NCS) is to measure indoor and outdoor concentrations and personal exposures of chi...
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STUDY OF CHILDREN'S BLOOD-LEAD LEVELS WITHIN FAMILIES |
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Comparative studies of the biological indices of elevated exposure to lead in children and adults were conducted with the intention of reaching a better understanding of lead absor...
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SUMMARY OF BIOLOGICAL AND ENVIRONMENTAL MONITORING RESULTS FROM THE AGRICULTURAL HEALTH STUDY/PESTICIDE EXPOSURE STUDY |
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The Agricultural Health Study (AHS) is a prospective epidemiologic study of pesticide applicators and spouses in Iowa and North Carolina. Exposure to 2,4-D or chlorpyrifos was m...
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TESTING DUPLICATE DIET SAMPLE COLLECTION METHODS FOR MEASURING PERSONAL DIETARY EXPOSURES TO CHEMICAL CONTAMINANTS |
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Dietary ingestion may be a significant pathway of human exposure to many potentially toxic chemicals. The U.S.Environmental Protection Agency-National Human Exposure Laboratory has...
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THE CTEPP DATABASE |
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The CTEPP (Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants) database contains a wealth of data on children's aggregate exposures to pol...
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THE DETROIT CHILDREN'S HEALTH STUDY: AN EXAMINATION OF THE EFFECTS OF AMBIENT AIR EXPOSURE ON THE RESPIRATORY HEALTH OF ASHMATIC CHILDREN |
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The United States has experienced a significant increase in childhood asthma since the late 1980s. EPA's Office of Children's Health Protection estimates that one out of every fift...
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THE DETROIT CHILDREN'S HEALTH STUDY: AN EXAMINATION OF THE EFFECTS OF AMBIENT AIR EXPOSURE ON THE RESPIRATORY HEALTH OF ASTHMATIC CHILDREN |
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The United States has experienced a significant increase in childhood asthma since the late 1980s. EPA's Office of Children's Health Protection estimates that one out of every fift...
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THE FEASIBILITY OF PERFORMING CUMULATIVE RISK ASSESSMENTS FOR MIXTURES OF DISINFECTION BY-PRODUCTS IN DRINKING WATER |
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Humans are exposed daily to complex mixtures of drinking water disinfection by-products (DBPs) via oral, dermal, and inhalation routes. Some positive epidemiological studies sugges...
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THE NATIONAL CHILDREN'S STUDY OF ENVIRONMENTAL EFFECTS ON CHILD HEALTH AND CDEVELOPMENT |
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The Children's Health Act of 2000 authorized a consortium of Federal agencies, including the U.S. Environmental Protection Agency (U.S. EPA), to develop and implement a prospective...
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THE NATIONAL CHILDREN'S STUDY OF ENVIRONMENTAL EFFECTS ON CHILD HEALTH AND DEVELOPMENT |
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Increasing recognition that children may be more susceptible than adults to environmental exposures and that they experience potentially life-long consequences of such exposures ha...
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THE NATIONAL CHILDREN'S STUDY: BEGINNING THE IMPLEMENTATION OF A NATIONAL-PROBABILITY SAMPLE |
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Introduction: The National Children's Study (NCS) is a longitudinal cohort study that will follow a sample of approximately 100,000 children born in the United States from before b...
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THE NATIONAL CHILDREN'S STUDY: PROGRESS DEVELOPING METHODS APPROPRIATE FOR ASSESSING CHILDREN'S EXPOSURE, BIOMARKERS AND GENETIC SUSCEPTIBILITY |
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Invited presentation: no abstract submission fee required
Introduction abstract for Workshop.
CONTROL ID: 56947
CONTACT (NAME ONLY): Barbara Abbott
Abstract Detai...
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THE NORTH CAROLINA HERALD PILOT STUDY |
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The sampling design for the National Children's Study (NCS) calls for a population-based, multi-stage, clustered household sampling approach. The full sample is designed t...
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THE THREE INTERACTING FACTORS ASSOCIATED WITH CHILDREN'S DIETARY EXPOSURES: ENVIRONMENTAL CONCENTRATIONS, FOOD CONTAMINATION, AND CHILDREN'S BEHAVIORS |
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The dietary contribution to an aggregate exposure assessment is potentially an important pathway of exposure especially for young children. Enviornmental contamination appearing in...
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THE UNIVERSITY OF AKRON STUDY ON AIR POLLUTION AND HUMAN HEALTH EFFECTS I. METHODOLOGY, BASELINE DATA, AND AEROMETRICS |
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This study determined the health effects of ambient air pollutants in two grade school populations in Akron, Ohio. One school is adjacent to industry and has elevated levels of sul...
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THE UNIVERSITY OF AKRON STUDY ON AIR POLLUTION AND HUMAN HEALTH EFFECTS II. EFFECTS ON ACUTE RESPIRATORY ILLNESS |
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The purpose of this study was to determine the effects of air pollution on acute respiratory illness (ARI). Levels of air pollutants were monitored on a daily 24-hour basis at two ...
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THE USE OF BOX MODELS TO DESCRIBE THE PERSONAL CLOUD EFFECT ON HUMAN EXPOSURE TO PARTICULATE MATTER |
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An algorithm has been developed to describe particle transport into and out of the breathing zone in an effort to predict the effects of the personal cloud phenomenon (Eisner and...
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THE VALUE OF HOME-BASED COLLECTION OF BIOSPECIMENS IN REPRODUCTIVE EPIDEMIOLOGY |
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The Value of Home-Based Collection of Biospecimens in Reproductive Epidemiology
John C. Rockett1, Germaine M. Buck2, Courtney D. Johnson2 and Sally D. Perreault1
1Reproductiv...
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TIME-INTEGRATED EXPOSURE MEASURES TO IMPROVE THE PREDICTIVE POWER OF EXPOSURE CLASSIFICATION FOR EPIDEMIOLOGIC STUDIES |
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Accurate exposure classification tools are required to link exposure with health effects in epidemiological studies. Although long-term integrated exposure measurements are a cri...
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TOWARDS USING STABLE SPERMATOZOAL RNAS FOR PROGNOSTIC ASSESSMENT OF MALE FACTOR FERTILITY |
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Objective: To establish the stability of spermatozoal RNAs as a means to validate their use as a male fertility marker.
Design: Semen samples were randomly selected for 1 of 3 ...
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TRAFFIC-RELATED AIR POLLUTION AND CHILDREN'S RESPIRATORY HEALTH: BEYOND PROXIMITY TO MAJOR ROADWAYS |
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Introduction: Previous studies of the respiratory health impact of mobile source air pollutants on
children have relied heavily on simple exposure metrics such as proximity ...
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TRANSFER OF PESTICIDES FROM SURFACES TO FOODS FOR THE ESTIMATION OF DIETARY EXPOSURE OF CHILDREN |
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Since small children spend much of their time in contact with contaminated surfaces, residues of pesticides found on floors and other surfaces contribute to their aggregate exposur...
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TRANSLOCATION AND REDISTRIBUTION OF PESTICIDES APPLIED IN THE RESIDENTIAL ENVIRONMENT |
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Pesticides are introduced into the indoor environment for pest control by direct application (e.g., insect sprays and bombs). They are also applied outdoors on lawns, in gardens...
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TRANSPORT OF LAWN-APPLIED 2,4-D FROM TURF TO HOME: ASSESSING THE RELATIVE IMPORTANCE OF TRANSPORT MECHANISMS AND EXPOSURE PATHWAYS |
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Transport of 2,4-D from the residential lawn into the home was measured following both homeowner and commercial application of this herbicide. Collection of floor dust in five ro...
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The Application of Physiologically Based Pharmacokinetic Modeling to Determine Route-Specific Contributions to Tissue Dosimetry of Trihalomethanes in Drinking Water |
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This project summary describes an improved approach for estimating route-specific exposures and tissue doses for trihalomethane (THM) compounds found in drinking water.
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