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Research Programs
Endocrine Disruptors Effects Research
Endocrine Disruptors
Effects Research
In recent years, scientists have been concerned about the possibility that certain chemicals can disrupt the endocrine system of humans and wildlife. A variety of chemicals have been found to do this in animals in laboratory studies, and there is compelling evidence that chemical contaminants have caused developmental and reproductive problems in certain fish and wildlife species.
Collectively, chemicals with the potential to interfere with the functioning of endocrine systems are called "endocrine disrupting chemicals" or "EDCs." The endocrine system regulates all biological processes in the body from conception through adulthood and into old age. These processes include the development of the brain and nervous system, the growth and function of the reproductive system, as well as metabolism and the regulation of blood sugar levels. The female ovaries, male testes, plus the pituitary, thyroid, and adrenal glands are major components of the endocrine system.
Humans and animals are exposed to EDCs through direct contact with chemicals such as insecticides, herbicides, fumigants, and fungicides; and they are indirectly exposed through ingestion of contaminated water or food. Industrial workers can be exposed at work to potential EDCs such as detergents, resins, and plasticizers. Endocrine disruptors enter the environment as a result of many manufacturing processes and when plastics and other materials are burned.
If you are new to the topic of endocrine disruption you might want to read the Endocrine Disruptors Screening Program (EDSP) Overview and EDSP Primer or visit one of the related links in the "Additional Information" section.
Read more about EPA's planned research on the health effects of EDCs.
