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abiraterone acetate An orally active acetate salt of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.
Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Code name: | ![](https://webarchive.library.unt.edu/eot2008/20081009172459im_/http://cancernet.nci.nih.gov/images/spacer.gif) | CB7630 | | ![](https://webarchive.library.unt.edu/eot2008/20081009172459im_/http://cancernet.nci.nih.gov/images/spacer.gif) |
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