Target Antigens of Transmission Blocking Antibodies for Malaria Parasites
Description of Invention:
This invention is a continuation of U.S. Patent Application 07/912,294, which described Pfs28 a 28 kd protein found in Plasmodium gallinaceum. The new application describes a unique 28 kd protein expressed on the surface of ookinetes of Plasmodium falciparum (Pfs28). This protein is useful as a malaria transmission blocking vaccine. This technology contains claims to: the Pfs28 protein; Pfs28's amino acid and nucleic acid sequences; pharmaceutical compositions containing the polypeptide and nucleic acid sequences; and methods of preventing transmission of malaria using these pharmaceutical compositions.
Inventors:
David C. Kaslow (NIAID) Patrick E. Duffy (NIAID)
Patent Status:
DHHS Reference No. E-149-1992/1 --
U.S. Patent No. 5,527,700 issued 18 Jun 1996
U.S. Patent No. 5,753,238 issued 19 May 1998
For Additional Information Please Contact: Robert M. Joynes J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301)594-6565
Email: joynesr@mail.nih.gov
Fax: (301) 402-0220
